HsaINT0103743 @ hg19
Intron Retention
Gene
ENSG00000108292 | MLLT6
Description
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 [Source:HGNC Symbol;Acc:7138]
Coordinates
chr17:36871865-36873234:+
Coord C1 exon
chr17:36871865-36872081
Coord A exon
chr17:36872082-36872619
Coord C2 exon
chr17:36872620-36873234
Length
538 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGT
5' ss Score
10.67
3' ss Seq
TGTTTCCCCTCTGTGCACAGTCT
3' ss Score
9.24
Exon sequences
Seq C1 exon
GTCTCCTCCTCGGCTTCCTCTTCCTCCCACCACGAGGCCAGCACGCAGGAGACCTCTGAGAGCAGCAGGGAGTCAAAGGGGAAAAAGTCTTCCAGCCATAGCCTGAGTCATAAAGGGAAGAAACTGAGCAGTGGGAAAGGTGTGAGCAGTTTTACCTCCGCCTCCTCTTCTTCCTCCTCCTCTTCCTCCTCCTCTGGGGGGCCCTTCCAGCCTGCAG
Seq A exon
GTGAGTGTGGGCATCCGGGAGGAAGCTGGGAGCAGGGAAAGCCTTTTGTCCTGAGCTTTTCTGGCAAGGGACTTTGCATATTGGTTTTGCATCTCATTTACTTCTCCATTGGTTCAGGATAAAGATGGGGAATCCCCTCCTCTCCAAACCTGCCCCCAAACCCTTCCTTCTTGAACCAGAACTCTCCTCTCCCCTTCAGGGGCCACCCCACCAACCTCATAACAGTATTCCTTATCCCCTACATTTGTGCTGCAAGGTACAATTTTTCAAGAACCCCCATTAACATTTTCTCCTATAATCGCTACAGTCATCTGGTGAGGCCAGTAGGGTGCGAGTTACTCTCCCCCATTTTATTACAGGTGGGAAAGCTGGAGGGGTCGGGGGTACTCATCCCAGGACACAGACAGTGGCAGAGCTGAGACAGGAAACCAGGCATCCCCATTCGTGGACCAGAGCTCTCTCCCGCCAGTACACGCGGGAGTGGGAGGGAGTGCGGGGATCTGGGGTCCAGCTGTAACTGTTTCCCCTCTGTGCACAG
Seq C2 exon
TCTCGTCCCTGCAGAGCTCCCCTGACTTCTCTGCATTCCCCAAGCTGGAGCAGCCAGAGGAGGACAAGTACTCCAAGCCCACAGCCCCCGCCCCTTCAGCCCCTCCTTCTCCCTCAGCTCCCGAGCCCCCCAAGGCTGACCTTTTTGAGCAGAAGGTGGTCTTCTCTGGCTTTGGGCCCATCATGCGCTTCTCCACCACCACCTCCAGCTCAGGCCGGGCCCGGGCGCCCTCCCCTGGGGACTATAAGTCTCCCCACGTCACGGGGTCTGGGGCCTCGGCAGGCACCCACAAACGGATGCCCGCACTGAGTGCCACCCCTGTGCCTGCTGATGAGACCCCTGAGACAGGCCTGAAGGAGAAGAAGCACAAAGCCAGCAAGAGGAGCCGCCATGGGCCAGGCCGTCCCAAGGGCAGCCGGAACAAGGAGGGCACTGGGGGCCCAGCTGCCCCATCCTTGCCCAGTGCCCAGCTGGCTGGCTTTACCGCCACTGCTGCCTCACCCTTCTCTGGAGGTTCCCTGGTCAGCTCCGGCCTGGGAGGTCTGTCCTCCCGAACCTTTGGGCCTTCTGGGAGCTTGCCCAGCTTGAGCCTGGAGTCCCCCTTACTAGGGGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000108292-MLLT6:NM_005937:9
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=1.000 A=NA C2=0.864
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAGCAGTGGGAAAGGTGTGAG
R:
CCGTGACGTGGGGAGACTTAT
Band lengths:
356-894
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)