HsaINT0104631 @ hg19
Intron Retention
Gene
ENSG00000196199 | MPHOSPH8
Description
M-phase phosphoprotein 8 [Source:HGNC Symbol;Acc:29810]
Coordinates
chr13:20242517-20244503:+
Coord C1 exon
chr13:20242517-20242671
Coord A exon
chr13:20242672-20244375
Coord C2 exon
chr13:20244376-20244503
Length
1704 bp
Sequences
Splice sites
5' ss Seq
AAGGTAAGC
5' ss Score
10.22
3' ss Seq
CACACATCTCCCATTTTCAGGCT
3' ss Score
9.67
Exon sequences
Seq C1 exon
ACTTTCAAGAGTAGCAGAAGAGACAATAAAGGATTACTTTGAAGCTCGCCTTGCTCTGCTAGAACCAGTTTTTCCAATCGCATGTCATCGACTCTGTGAGGGTCCAGATTTTTCAACAGATTTCAATTACAAACCCCCACAGAACATACCAGAAG
Seq A exon
GTAAGCCGATGCCTCCCTTCACACTTTTCTATGTGAAGTGTGACACTATATTAACAGATTTTTAGACAGAATCCTTTCTTGGAACAAAACTTTAAGGAAATTCCATTACGTGTAATAATTCTGCAGACCGGTTAACAGTAGAGCCACTCTGGTGGAAGAGACATCCAGCTGACACCCCATCCCTGTTTTAACACCCATATAGAGCATGGAAGTTAGGTCTTAATAATCACACTAGTTCTCAATGAGTTTTATTAAAATTCAGCGTCAAGATTCTAAGCCTAGAATGTTTTTTCCCTGAATTTTGTTGTTTGTAATAGTCTTTGCCCTTTGAAAAAGAAAAAAATAGTCTTGCTCCATAGTAAAGCTGAGTGGAAAGAGATGGAGAAGCCACTTTCCTCTCTAGCCTCTGCTCGACAGACCCTCTCCAGGCAGGGCTGCGGCTGGCCCTCTCTACACGTGGCGCCAGGTAGACGTGGAGGCAGTGCAGTCTGCCGAGGGGAGGAAGCCGGGCTCTGGCTTTTTTTGCTTAGAAACTCCTGTTCCCCATTTTGTAAATGGTTTGTATTCATTCCTGGAAAATGTATTTAAGAACATATAGCCCTGCCCCTGAAAGAGCCGTTTGTAATATCTTAGTGTTGAGAGAACTTATCAGGTGGTTGCTGTTGTTTTGAGATGGAGTCTCCCTGTGTCACCCAGGCTGCAGTGCATGGCATGATCTTGGCTCACTGCAACCTCTGCCTTCTGGCTTCAAGTGATCCGCCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGTGCGCGTTCAGTAATTTATAGTTTTGATTATTCGGGTGGACCATCTGCATTGCCAGGTATGAGTACCAGAGAACGATGCCCTGAGCTGGCCCTGGTGAACCTGAGCCCCCACTGACACCTACAACTGCTGGGCCTGCAGTTTTCTCAGCATGTGTACAATGTCTGCATCCACCAACTTTTTTTTTTTTTTTTCAGGAGTCTCACACTGTTCCCCAGGCTGGAGTGCAGTGGTGCGATCTCGGCTCACTGCAACCTCCGCCTCCTGGGTTCAAGCAATTCTCCTGCCTCAACCTCCCGAGTAGCTGGAATTACAGGTGCCCACCATGATACCCAGCTAAATTTTGTGTTCTTAGTAGAGATGGGGGTTTCACCATATTGGCCAGGCTGATCTTGAACTCCTGGCCTCAAGTGATCTGCCTGCCTCTGCCTCCCAAAGTGCTGGGATTACAGACATGAGCCACCATGCCTGGCCAATTTTTGGTTATGTATTAATCAGAAAAATTGGAAGGGGCAAAAGGGTATGTGGAAGAAAATGGAAAACCACTCAGACCCACACCCAAAGATGCCCACCACAGGAATGTCCCTGGGACGTGTGCACATTCAGCAGCAGTGTTTAAATACCAGTTAAATAACTTCAGTGTAGAAAATCATACGTAAGTCTTTTCCAGGAACTGTCAGCAGAGATTACTTGGGCAAAAGGTAAAAAGAGTTCTGTGGTTGAAAAATGCCAGGTGACACGAGCTTTGAGAGGGCCAGCCTCCTCTGAGCCTCCAGGCAGAGTGGGTGATGCCTGTCTGACCAGGCCCAGCTCAGGGGCCTGCTTCCATCTGGTGTTGAGTGTTCCTCTGGGGACTGAAGGTTGCCTTTGAAGTAATTCACACACATCTCCCATTTTCAG
Seq C2 exon
GCTCTGGCATCCTGCTGTTTATCTTCCATGCAAACTTTTTGGGTAAAGAAGTTATTGCTCGGCTCTGTGGACCGTGTAGTGTACAAGCTGTAGTTCTGAATGATAAATTTCAGCTTCCTGTTTTTCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000196199-MPHOSPH8:NM_017520:11
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.021 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACTTTCAAGAGTAGCAGAAGAGACA
R:
GAAAAACAGGAAGCTGAAATTTATCA
Band lengths:
281-1985
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)