HsaINT0106398 @ hg19
Intron Retention
Gene
ENSG00000198793 | MTOR
Description
mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]
Coordinates
chr1:11187681-11188183:-
Coord C1 exon
chr1:11188061-11188183
Coord A exon
chr1:11187864-11188060
Coord C2 exon
chr1:11187681-11187863
Length
197 bp
Sequences
Splice sites
5' ss Seq
ATGGTGGGT
5' ss Score
6.18
3' ss Seq
CCTTCTTCTCTTGGCTTCAGGTG
3' ss Score
11.09
Exon sequences
Seq C1 exon
GCCCTCATCTACCCACTGACAGTGGCTTCTAAGTCTACCACGACAGCCCGGCACAATGCAGCCAACAAGATTCTGAAGAACATGTGTGAGCACAGCAACACCCTGGTCCAGCAGGCCATGATG
Seq A exon
GTGGGTCGGAGCCACTGTGGGGCTTCATAGACCCTGGTCCCTTAGCTGGTGGGCGCAAGTGGGATTGTTTTTCTTCCTCGCATTGGTGCTGTGCACTTCCTCTGACTGCTGGAAATAGTACCTCCTGTGTCTCCAAAACAGACCTTTCTGAGGTTAGCTGATTCTTGATGCTTCTCTCCTTCTTCTCTTGGCTTCAG
Seq C2 exon
GTGAGCGAGGAGCTGATCCGAGTGGCCATCCTCTGGCATGAGATGTGGCATGAAGGCCTGGAAGAGGCATCTCGTTTGTACTTTGGGGAAAGGAACGTGAAAGGCATGTTTGAGGTGCTGGAGCCCTTGCATGCTATGATGGAACGGGGCCCCCAGACTCTGAAGGAAACATCCTTTAATCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000198793-MTOR:NM_004958:43
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.016
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF087716=Rapamycin_bind=PU(57.0=93.4)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCCCTCATCTACCCACTGACA
R:
CCAGCACCTCAAACATGCCTT
Band lengths:
244-441
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)