HsaINT0107473 @ hg19
Intron Retention
Gene
ENSG00000133026 | MYH10
Description
myosin, heavy chain 10, non-muscle [Source:HGNC Symbol;Acc:7568]
Coordinates
chr17:8411872-8413267:-
Coord C1 exon
chr17:8413130-8413267
Coord A exon
chr17:8411996-8413129
Coord C2 exon
chr17:8411872-8411995
Length
1134 bp
Sequences
Splice sites
5' ss Seq
AAAGTAAGA
5' ss Score
6.91
3' ss Seq
AGTCAATTTTTCCTGTCCAGGAA
3' ss Score
7.22
Exon sequences
Seq C1 exon
GACCTGGAAGAACAGCTAGACGAGGAGGAAGGGGCTCGGCAAAAGCTGCAGCTGGAAAAGGTGACAGCAGAGGCCAAGATCAAGAAGATGGAAGAGGAGATTCTGCTTCTCGAGGACCAAAATTCCAAGTTCATCAAA
Seq A exon
GTAAGAGAGTGTTCCCACAAAAAGCTGATTTTAGTTACAGAAAATATTTATATAATATTATGTTGATACACTCATTGAAAGTGAACTCAAACAGAAATTTCTCAAGATTTTAGGTTCATTTACTGAATTTTCTCTGTAAGTCTCTACTTGTATAGATTTCTAAAGATACAGGCACCATTGAATTTTTTAAACCTTATCAAATATCCTGATAATCTTTTAGACTTGTAACATGTGCAGTTTGTGCATAATGGTCACTCAATGATGACTTGTCTCCATCTGTGCAAGCATTAATTCATCCACCATTGACTGTGGGACTCTGAATACCAGGCAGCTGGGCCAAGCTCCCGGGGTGGGCACCAAGACGTGTAAGCCTTTCTGCCCTTTTGGAGTACAGTCGTGTGTTGTTTAACGATGAGGACACATTCTGGGAAATGCATTGTGAAGTTATTTTATCCTCGTACAAACATCATAGAGTGTATGGACACAAACTAGATGGTAGAGCCTGCTATACACCTAGACCAGACGCTGGGCTGATTGCATCTAGGCCACACACTTGTACAGCATGTTACTGTCCTGAATACTGTAGGCAGTTGGAACACAGTGCTAATAAGTACTTGTGTATCTAAACATATCCACACAAAAGTCCAGTAAAAATATGATAGAAAAGGTACGGTAAAAATGATAGAAAAGATTTAAAATGGCACACCTCTATTGGGCACTCACCATGAACGGAGCTTGCAGGACTGGAAGCTGCTCTGGGTGAGTCAGTGAGTGAGCGCTGAGTGAATGTGAAGGCCTAGGACATTGCTGTACATGACTGCAGACTTTATCAACATGGCACACTGAGGCTGCAGTACATTTATTTTAAAAATAGAGTAATTGCACTGTGGTGTTATGACAGCTCTCGATGAAGTTTTCAGCTCCATGATCATCTTAGGAGACCACTGTCGTGTATCCGGTTCATCATTGTCCAAAACATCGTTCTGCAGCATGTGATTGTGTACAGTCTGCTGGGGGAGGCAGTGCCGATAGAACTTATTTTCTCTCGAGTCAAAGTTGACCTTTATGAGGAATACAGAACCCAAGTGGTCATTCTGAATGGCTTTTCTGAAGCAGTCAATTTTTCCTGTCCAG
Seq C2 exon
GAAAAGAAACTCATGGAAGATCGCATTGCTGAGTGTTCCTCTCAGCTGGCTGAAGAGGAAGAAAAGGCGAAAAACTTGGCCAAAATCAGGAATAAGCAAGAAGTGATGATCTCAGATTTAGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000133026-MYH10:NM_005964:23
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.370 A=NA C2=0.524
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=FE(19.1=100)
A:
NA
C2:
PF0157614=Myosin_tail_1=FE(17.4=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACCTGGAAGAACAGCTAGACGA
R:
ATCTGAGATCATCACTTCTTGCT
Band lengths:
254-1388
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)