HsaINT0107513 @ hg38
Intron Retention
Gene
ENSG00000133392 | MYH11
Description
myosin heavy chain 11 [Source:HGNC Symbol;Acc:HGNC:7569]
Coordinates
chr16:15740051-15741669:-
Coord C1 exon
chr16:15741463-15741669
Coord A exon
chr16:15740189-15741462
Coord C2 exon
chr16:15740051-15740188
Length
1274 bp
Sequences
Splice sites
5' ss Seq
CTGGTAAGG
5' ss Score
9.68
3' ss Seq
CTTTTCCCTCCACAACAAAGGAC
3' ss Score
3.45
Exon sequences
Seq C1 exon
CTGACCGAGGAGAAGAACCTGCTACAGGAACAGCTGCAGGCAGAGACAGAGCTGTATGCAGAGGCTGAGGAGATGCGGGTGCGGCTGGCGGCCAAGAAGCAGGAGCTGGAGGAGATACTGCATGAGATGGAGGCCCGCCTGGAGGAGGAGGAAGACAGGGGCCAGCAGCTACAGGCTGAAAGGAAGAAGATGGCCCAGCAGATGCTG
Seq A exon
GTAAGGTGTCACAGGGGCAGCCCGTGGTGGGTAGCAAATCACTTGACCCTCACCACAGGCCTGTGGAGGTGCATCCAGGGATATGTGTCCCTGCTGGGACAGATGATGAGACGGGGGCTTGGAGAGGGTTGGTCATCTGATCAAGGCCACACAGCTGGGATTGGGACTGGAACACAGTGAGCCCACTCTGTTCTATTGCCCTGCCTTGCATGTGCTAACCCCTTTTCTCCTAACAGCAAGCCTGAATGGAGGATAATTGTATTTGTTAGCTATTGCTACATAACAAAACATGCCAAACTCAGCAGCTAAAAATAAAAAGTATTGCATAGTCAGGAATTTGAGAGTGGCTTAGGTGAGTGGTTCTGGCTGAGGGTCCGGCCTGAGGTTGCAGTCAAGGTGTTGGCTGAGGCTGCAGTCATCTGAAGGCTCATCTGGGGCTGGAGGACCCACTTCTACTTGGCTTATTCACACAGCTGTTGGAGGAGGCCTCAGTTCCTTATCATGAAGGCCTCTCCCCTCAGGGCTGCTTGAGTGTCCTTCCAATATGGCAGCAGAGTTCCCCCAGAAGGAGTGATCTGAGAGAGGAGAAAGGAAGCCGCAATGCCTTTTATAGCCTAATCTCTGAAGTTACATTCCATCACTTCTTCCTGATTTTTGTTGTTGTTGTTAGAAGCAAATCTAACCCCCACTCAAGGGGAGGAGAATTAGGCTCCACCTTTTTGGAGTCGCAAAGAACTTGTGGATAGATTTTAAAACCACCATGGTACCTACTGTGCTCATTTTATAGATGAGGAGGTTGAGGTTCCATGAAGCAGAGCAGCTTACCCAGGTCTTTATTTTTTTTTTTTTTTTGAGACAGAGTCTCACTCTCTTGCCTAGGCTGGGGTGCGATGGTGCGATCTCAGCTCACTGCAACCTCTGCCTCTCGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGAGCCCACCACCATGCCTGGCTAATTTTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTGGCCAGGCTGGTCTTGAATTCCTGACCTCAAGTGATCCACCCACCTCGGCCTCCAAAAGTGCTGGGATTACAGGTGTGAGCCACCACGCTCAGGCCTTTATTTCTTCCTTTTAGGAGGCTACAGAGTTCTGGGCATCTTCAGGCCTAGCCCCTGTATTCATTAGTCCCCAGATCACCACGAGAGTAAATCTGTTATAACCAAAGCTGTTACTCTTTTCCCTCCACAACAAAG
Seq C2 exon
GACCTTGAAGAACAGCTGGAGGAGGAGGAAGCTGCCAGGCAGAAGCTGCAACTTGAGAAGGTCACGGCTGAGGCCAAGATCAAGAAACTGGAGGATGAGATCCTGGTCATGGATGATCAGAACAATAAACTATCAAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000133392:ENST00000300036:22
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.507 A=NA C2=0.457
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=PU(9.5=20.3)
A:
NA
C2:
PF0157614=Myosin_tail_1=FE(30.6=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGACCGAGGAGAAGAACCTG
R:
TATTGTTCTGATCATCCATGACCAGG
Band lengths:
334-1608
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development