HsaINT0107517 @ hg19
Intron Retention
Gene
ENSG00000133392 | MYH11
Description
myosin, heavy chain 11, smooth muscle [Source:HGNC Symbol;Acc:7569]
Coordinates
chr16:15826421-15829435:-
Coord C1 exon
chr16:15829223-15829435
Coord A exon
chr16:15826566-15829222
Coord C2 exon
chr16:15826421-15826565
Length
2657 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGG
5' ss Score
10.07
3' ss Seq
ACTGTGTTCCTCCCACCAAGGGC
3' ss Score
6.49
Exon sequences
Seq C1 exon
GCTTGACGATGAAATCGCTCAGAAGAACAATGCCCTGAAGAAGATCCGGGAGCTGGAGGGCCACATCTCAGACCTCCAGGAGGACCTGGACTCAGAGCGGGCCGCCAGGAACAAGGCTGAAAAGCAGAAGCGAGACCTCGGCGAGGAGCTGGAGGCCCTAAAGACAGAGCTGGAAGACACACTGGACAGCACAGCCACTCAGCAGGAGCTCAG
Seq A exon
GTGAGGGGCCCATCAATCCCACCATCCTGCTATCCCACTGCACCAATGGGATGGGGGCAGAAGAGGGGACAAACCCAAAGCAAATCGTGCATCAGCCCCTGTGCATTTACCTTCCTGGCCGCGGTTTGCTTTAACTTATAGAAGCATGGTTGGCTGTTTCTTTTTTTTCTTTCTTTTTTTTTTTTTTTTGAGGCAGTCTGGCTTTGTTGCCTAGGCTGGAGTGCAGTTGTGCCATCTTGGCTCACTGCAACCTCCACCTCTGAGATTTAAGCGATTCTCATGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGTATGTGCCACCACACCCGGCTAATTTTTTGTTTTTAGTAGAGATGGAGTTTTGCCATGTTGCCCAGGCTGGACTTGAACTCCTGGCCTCAAGTGATCCACCCACTTCCGCCTCCCAAACTGCTGGTATTACATGTGTGAGCCACTGCACCCGACCCTCATCATCTTATTTCTCATCAGAAGAGTAGTATATACCAGGGATGTACAATCTTTTGGCTTCCCTTGGCCACATTGGAAGAAAAAGATTTGTCTTGGGCCACACATAAGATACACTAACACTAATAATAGCTGATCAACTAAAAAAATTTTACAAATTGGAAAAAACATCTCATACTGTTTTAAGAAAGTTTATGACTCTGTGTCAGGCTGCATTCAAAACCATCCTCATTGGTAAGCTTGGATATACTCAGAGAACAATTTGAAAACTATAGAAAAGCAGACATAAAAAAAAATCACCTTTAGGGTCGGGCTCACGCCTATAATCTCAGCACTTTGGGAGGCCAAAGACAGGTGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCTGTCTCTACTATAAATCCAAAAATTACCTGGGCGTGGTGGCGCATGCCTGTAAATCCCAGCTACTCAGGAGGCTGAGGCAGTAGAGTCACTTGAATCTGGGAGGCAGAGGTTGCAGTGAGCTGAGATCGCACCATCGCACTCCAGCCTGGGTGACACAGTGAGTGAGACTCCATCTCAAAAAAAAACAAAAAACAAAAAAATCACCCTTAGTCACACCAGTTAACATTCTTGAGAAATTCCTTCCTGTCTGTGTGTGTATCAGTCAGTCCCCAAGCTCCAATTCCCAAGTATGTGTGTGTATCACTTTTGTGTTAAATTTTAAAAATAAAATTGATCAGATTGGTTTTCAATTGAAGATTCACTTCAAATGAACAAACAATAACAAACTGCCTGCCAGATCACGAATCCTGACTCTAGTGAAACTAGGTCATTGATTCATTCAGTAAACACATAAATGTATTTTGATGCAATCTGTGGTGTTGGCATAGCATGTATCATAGCATATAGCTATGCTAGCTGTGCCAACACCATATACCCTGGGGTTTACTTCCCCCACTTTGGGTTTTGTGCAGTGTCACATGCACATAGAGCACAGCGTTCTGCTCCCTTGCCGCTTGGCCTTTGATACAGAAGAGCCCAGTGCATGGGCCAGGTATGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCTGAAGCAGACAGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATCATGAAAACCTGTCTCTACTAAAAAGACAAAAATTAGCCGGGCGTGGTGGTGGGCGTCGGTAATCCCAGCTACTTGGGAGACTGAGGCAGGAGAATCCCTTGAACCTGGGAGGCAGAGGTTGCAGTGAGCTGACATCATTCCACTGTACTCCAGTCTGGACGACGGAGCAAGACTCGATAAGAAAAACAAACAAACAAAACAAAAAACCAGGCTGAGTGCGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGTGGATCACCTGAGGTCAGGAGTTCGAAACCAGCCTGACCAACATGTTGAAACCCCATCTCTACTAAAAATATAAAATTAGCCGGGCGTGGTGGTGGGCACCTGTAATCCCAGCTACTTAGGAGGCCGAGGCAGGAGAATCGCTTGAACCCGGGAGGTGGAGGTTGCAGGGGGCCAAGATTGCGCTGTCGCACTCCAGCCTGGGCAACAGGAGTGAAACTCCATCTCAAAAACAAACAAACAAAACCATGGACTCAAGGTCAAGGTTTAGCTTCTAATTCTGGCTCCATCACACAATGGCTGTGACACCATGGGTAAAACTGCTTACCCTCTCTTAGCCTTAGTTTCCTCATTTGTAAAATGGAAATAATAACACACCTGCCTCTTTGGGTTGCTCTGAGGATTAGATGATGTATATAAAAAACTTAGCTCAGGGCCTGGCATATAGTAACTGCTCATTAAATAAGAGCCAACATTAATATTTAAGCAAAATTTTGCAGTTCACAGACATCCTTTCAATTCTATTACTTTGTGTATTTGTTTGCCAGTCATTACAGATGTCCTAGGCAGGTGATATGCTCCACATTTTGCAGCTGAGGAAATTTTAGGTCCAGAGATGTTAGGTGAATGACCCAAGGTCACACAGCTAGAGAGGGGTGGTGATGAGGACTGCAGCTCTGGGTCCTGGAAGAGCTCTCATTCTTTTGCACGGCACTGAGATGACCCTCTGTCTCCACCCAACTGCCATTCACTGTGTTCCTCCCACCAAG
Seq C2 exon
GGCCAAGAGGGAGCAGGAGGTGACGGTGCTGAAGAAGGCCCTGGATGAAGAGACGCGGTCCCATGAGGCTCAGGTCCAGGAGATGAGGCAGAAACACGCACAGGCGGTGGAGGAGCTCACAGAGCAGCTTGAGCAGTTCAAGAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000133392-MYH11:NM_001040113:27
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.806 A=NA C2=0.898
Domain overlap (PFAM):
C1:
PF0003816=Filament=FE(27.6=100),PF0157614=Myosin_tail_1=FE(8.3=100)
A:
NA
C2:
PF0003816=Filament=FE(18.7=100),PF0157614=Myosin_tail_1=FE(5.6=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)