HsaINT0107735 @ hg19
Intron Retention
Gene
ENSG00000109063 | MYH3
Description
myosin, heavy chain 3, skeletal muscle, embryonic [Source:HGNC Symbol;Acc:7573]
Coordinates
chr17:10542361-10542791:-
Coord C1 exon
chr17:10542615-10542791
Coord A exon
chr17:10542507-10542614
Coord C2 exon
chr17:10542361-10542506
Length
108 bp
Sequences
Splice sites
5' ss Seq
GACGTAAGT
5' ss Score
10.93
3' ss Seq
GGAAATGGTGCCTTTTTCAGCTG
3' ss Score
5.93
Exon sequences
Seq C1 exon
GTTAAAAACCTTACTGAGGAACTCTCTGGGTTAGATGAAACAATTGCAAAGTTAACCAGAGAGAAGAAGGCCCTCCAAGAGGCGCACCAGCAGGCCTTGGATGACCTCCAAGCTGAAGAAGACAAAGTCAATTCTTTGAACAAAACCAAGAGCAAACTGGAACAGCAAGTGGAAGAC
Seq A exon
GTAAGTAAATAATGCTCATCGGGAGTCCCAGAACTCCAGGGTTGGAAGAGCCCTCAAGGGTCCTCTTGCAAAGCATTTGTTCCCAAAAGGAAATGGTGCCTTTTTCAG
Seq C2 exon
CTGGAAAGCTCCCTAGAACAAGAAAAGAAGCTCCGAGTAGACCTGGAAAGGAACAAAAGGAAATTGGAAGGAGACTTGAAGCTTGCTCAAGAGTCCATATTAGATCTGGAGAATGACAAGCAACAGCTGGACGAAAGGCTCAAGAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000109063-MYH3:NM_002470:23
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.729 A=NA C2=0.020
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=FE(29.4=100),PF0157614=Myosin_tail_1=PU(46.3=52.5)
A:
NA
C2:
PF0157614=Myosin_tail_1=PD(1.0=4.1),PF0157614=Myosin_tail_1=PD(50.7=69.4),PF0157614=Myosin_tail_1=PU(1.6=28.6)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGAGAAGAAGGCCCTCCAAGA
R:
AGCCTTTCGTCCAGCTGTTG
Band lengths:
258-366
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)