HsaINT0107735 @ hg38
Intron Retention
Gene
ENSG00000109063 | MYH3
Description
myosin heavy chain 3 [Source:HGNC Symbol;Acc:HGNC:7573]
Coordinates
chr17:10639044-10639474:-
Coord C1 exon
chr17:10639298-10639474
Coord A exon
chr17:10639190-10639297
Coord C2 exon
chr17:10639044-10639189
Length
108 bp
Sequences
Splice sites
5' ss Seq
GACGTAAGT
5' ss Score
10.93
3' ss Seq
GGAAATGGTGCCTTTTTCAGCTG
3' ss Score
5.93
Exon sequences
Seq C1 exon
GTTAAAAACCTTACTGAGGAACTCTCTGGGTTAGATGAAACAATTGCAAAGTTAACCAGAGAGAAGAAGGCCCTCCAAGAGGCGCACCAGCAGGCCTTGGATGACCTCCAAGCTGAAGAAGACAAAGTCAATTCTTTGAACAAAACCAAGAGCAAACTGGAACAGCAAGTGGAAGAC
Seq A exon
GTAAGTAAATAATGCTCATCGGGAGTCCCAGAACTCCAGGGTTGGAAGAGCCCTCAAGGGTCCTCTTGCAAAGCATTTGTTCCCAAAAGGAAATGGTGCCTTTTTCAG
Seq C2 exon
CTGGAAAGCTCCCTAGAACAAGAAAAGAAGCTCCGAGTAGACCTGGAAAGGAACAAAAGGAAATTGGAAGGAGACTTGAAGCTTGCTCAAGAGTCCATATTAGATCTGGAGAATGACAAGCAACAGCTGGACGAAAGGCTCAAGAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000109063:ENST00000583535:24
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.729 A=NA C2=0.020
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=PD(28.8=93.2),PF0157614=Myosin_tail_1=PU(45.5=50.8),PF0003816=Filament=PU(6.9=32.2)
A:
NA
C2:
PF0157614=Myosin_tail_1=PD(1.0=4.1),PF0157614=Myosin_tail_1=PD(50.7=69.4),PF0157614=Myosin_tail_1=PU(1.6=28.6)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGAGAAGAAGGCCCTCCAAGA
R:
AGCCTTTCGTCCAGCTGTTG
Band lengths:
258-366
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development