HsaINT0107741 @ hg19
Intron Retention
Gene
ENSG00000109063 | MYH3
Description
myosin, heavy chain 3, skeletal muscle, embryonic [Source:HGNC Symbol;Acc:7573]
Coordinates
chr17:10538157-10538880:-
Coord C1 exon
chr17:10538684-10538880
Coord A exon
chr17:10538341-10538683
Coord C2 exon
chr17:10538157-10538340
Length
343 bp
Sequences
Splice sites
5' ss Seq
CAAGTGCGC
5' ss Score
4.41
3' ss Seq
TCTCTTTCATATTCTTTAAGGAA
3' ss Score
8.51
Exon sequences
Seq C1 exon
GCCAAGAACGCCCTGGCGCACGCCCTGCAGTCCTCCCGCCACGACTGTGACCTGCTGCGGGAACAGTATGAGGAGGAGCAGGAAGGCAAAGCTGAGCTGCAGAGGGCGCTGTCCAAGGCCAATAGTGAGGTTGCCCAGTGGAGAACCAAATACGAGACGGACGCCATCCAGCGCACAGAAGAGCTGGAGGAGGCCAA
Seq A exon
GTGCGCAGCTCTGTTTGCTTTTAGAAGAACTACTTAGGAATGAATTCGATGAATTTATTTTTATTACTAGGCGTTTCCCCATCTCATGTGTCTTTAAATGCGGTGCTGGGCCATTAGAGGGACCTGGCGTTAGCACATTTTATTAAAACAAACAGCTTTGATCTTGGTCAGACACAAGGCAAGTTATTGATCCCAGATTTTGAGTAGACAGGAAATTCTCCTGGGCGTATAAAAACACATGGGTGTCTGAATCACATAGATTAGTGATTCCAACTTGATGAATAGTGATGTTCAAGTGGATGGAAACTGAAATAACAGCTGCTTCTCTTTCATATTCTTTAAG
Seq C2 exon
GAAAAAACTTGCTCAGCGCCTTCAAGATTCCGAGGAACAGGTTGAGGCAGTGAATGCTAAATGTGCTTCACTGGAGAAGACCAAGCAGAGGCTGCAAGGAGAGGTGGAGGATCTGATGGTTGATGTTGAAAGAGCCAATTCCTTGGCCGCCGCTCTGGACAAGAAGCAGAGGAACTTTGACAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000109063-MYH3:NM_002470:29
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.561 A=NA C2=0.258
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=FE(7.6=100)
A:
NA
C2:
PF0157614=Myosin_tail_1=FE(7.1=100),PF045827=Reo_sigmaC=PU(37.0=87.1)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAGTCCTCCCGCCACGAC
R:
CCTCTGCTTCTTGTCCAGAGC
Band lengths:
342-685
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)