HsaINT0107741 @ hg38
Intron Retention
Gene
ENSG00000109063 | MYH3
Description
myosin heavy chain 3 [Source:HGNC Symbol;Acc:HGNC:7573]
Coordinates
chr17:10634840-10635563:-
Coord C1 exon
chr17:10635367-10635563
Coord A exon
chr17:10635024-10635366
Coord C2 exon
chr17:10634840-10635023
Length
343 bp
Sequences
Splice sites
5' ss Seq
CAAGTGCGC
5' ss Score
4.41
3' ss Seq
TCTCTTTCATATTCTTTAAGGAA
3' ss Score
8.51
Exon sequences
Seq C1 exon
GCCAAGAACGCCCTGGCGCACGCCCTGCAGTCCTCCCGCCACGACTGTGACCTGCTGCGGGAACAGTATGAGGAGGAGCAGGAAGGCAAAGCTGAGCTGCAGAGGGCGCTGTCCAAGGCCAATAGTGAGGTTGCCCAGTGGAGAACCAAATACGAGACGGACGCCATCCAGCGCACAGAAGAGCTGGAGGAGGCCAA
Seq A exon
GTGCGCAGCTCTGTTTGCTTTTAGAAGAACTACTTAGGAATGAATTCGATGAATTTATTTTTATTACTAGGCGTTTCCCCATCTCATGTGTCTTTAAATGCGGTGCTGGGCCATTAGAGGGACCTGGCGTTAGCACATTTTATTAAAACAAACAGCTTTGATCTTGGTCAGACACAAGGCAAGTTATTGATCCCAGATTTTGAGTAGACAGGAAATTCTCCTGGGCGTATAAAAACACATGGGTGTCTGAATCACATAGATTAGTGATTCCAACTTGATGAATAGTGATGTTCAAGTGGATGGAAACTGAAATAACAGCTGCTTCTCTTTCATATTCTTTAAG
Seq C2 exon
GAAAAAACTTGCTCAGCGCCTTCAAGATTCCGAGGAACAGGTTGAGGCAGTGAATGCTAAATGTGCTTCACTGGAGAAGACCAAGCAGAGGCTGCAAGGAGAGGTGGAGGATCTGATGGTTGATGTTGAAAGAGCCAATTCCTTGGCCGCCGCTCTGGACAAGAAGCAGAGGAACTTTGACAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000109063:ENST00000583535:30
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.636 A=NA C2=0.315
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=FE(16.8=100),PF131661=AAA_13=FE(25.4=100),PF059116=DUF869=PD(17.5=25.8)
A:
NA
C2:
PF0157614=Myosin_tail_1=FE(7.1=100),PF045827=Reo_sigmaC=PU(37.0=87.1)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAGTCCTCCCGCCACGAC
R:
CCTCTGCTTCTTGTCCAGAGC
Band lengths:
342-685
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development