HsaINT0107816 @ hg19
Intron Retention
Gene
ENSG00000197616 | MYH6
Description
myosin, heavy chain 6, cardiac muscle, alpha [Source:HGNC Symbol;Acc:7576]
Coordinates
chr14:23858802-23859655:-
Coord C1 exon
chr14:23859266-23859655
Coord A exon
chr14:23858929-23859265
Coord C2 exon
chr14:23858802-23858928
Length
337 bp
Sequences
Splice sites
5' ss Seq
AAGGCAGGC
5' ss Score
2.32
3' ss Seq
TCCTGTCTTGCTTCCTGAAGGCA
3' ss Score
6.8
Exon sequences
Seq C1 exon
GCACGCATCGAGGAGCTGGAGGAGGAGCTGGAGGCCGAGCGCACCGCCAGGGCTAAGGTGGAGAAGCTGCGCTCAGACCTGTCTCGGGAGCTGGAGGAGATCAGCGAGCGGCTGGAAGAGGCCGGCGGGGCCACGTCCGTGCAGATCGAGATGAACAAGAAGCGCGAGGCCGAGTTCCAGAAGATGCGGCGGGACCTGGAGGAGGCCACGCTGCAGCACGAGGCCACTGCCGCGGCCCTGCGCAAGAAGCACGCCGACAGCGTGGCCGAGCTGGGCGAGCAGATCGACAACCTGCAGCGGGTGAAGCAGAAGCTGGAGAAGGAGAAGAGCGAGTTCAAGCTGGAGCTGGATGACGTCACCTCCAACATGGAGCAGATCATCAAGGCCAAG
Seq A exon
GCAGGCTCTGCTCGGCCTCCCCTCGCCCTCTCCCCTGCACAGCGGAGCCTCCCCCATGCCTTCTCTCTCTGTCTGCCATCTCCCTTGTCATTCTCATTCTCTTCATCACCCTTTGGTCTCTCTTCCTGTCTCCCCTGCCCCTCTCTGGCTCTCCTCACCCTCTCTATCTCTTCATGTTCCTCCTTTCTTTAATTCAAGTCTCTCTTCAGACTGCGCCCTCCCACACCTTCTGTGTCCCCCTCCTGCCCTCTGGCATTCCCCATCTCTGACCCTCTCTTCCTTCCTCTGGTCGACTCAGCCCCTCCCACACTCACCCTTCCTGTCTTGCTTCCTGAAG
Seq C2 exon
GCAAACCTGGAGAAAGTGTCTCGGACGCTGGAGGACCAGGCCAATGAGTACCGCGTGAAGCTAGAAGAGGCCCAACGCTCCCTCAATGATTTCACCACCCAGCGAGCCAAGCTGCAGACCGAGAATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197616-MYH6:NM_002471:26
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.531 A=NA C2=0.465
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=FE(15.0=100),PF0003816=Filament=PU(7.4=6.9)
A:
NA
C2:
PF0157614=Myosin_tail_1=FE(4.9=100),PF0003816=Filament=FE(34.7=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGATGAACAAGAAGCGCGAGG
R:
CTCGCTGGGTGGTGAAATCAT
Band lengths:
348-685
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)