HsaINT0107878 @ hg19
Intron Retention
Gene
ENSG00000078814 | MYH7B
Description
myosin, heavy chain 7B, cardiac muscle, beta [Source:HGNC Symbol;Acc:15906]
Coordinates
chr20:33572657-33572932:+
Coord C1 exon
chr20:33572657-33572749
Coord A exon
chr20:33572750-33572868
Coord C2 exon
chr20:33572869-33572932
Length
119 bp
Sequences
Splice sites
5' ss Seq
TTTGTGAGT
5' ss Score
5.91
3' ss Seq
GGCTGCCCCTCTGCCCACAGGGC
3' ss Score
11.15
Exon sequences
Seq C1 exon
GGCACCCTTGAGGATCAAATCATCGAGGCCAACCCTGCCATGGAGGCCTTTGGCAACGCCAAGACCCTGAGGAATGATAACTCCTCCCGCTTT
Seq A exon
GTGAGTGGCTGAGGTGGGAGGGGTGGCGGGGATGCCGTAGGCCACCAGCGGCAGGTCGGGCACAGGTGGGGACAGTGCTGGCTGTGCCCCTTGGCTGAGGGCTGCCCCTCTGCCCACAG
Seq C2 exon
GGCAAGTTCATCCGCATTCACTTTGGTCCCTCTGGGAAGCTGGCATCCGCGGATATTGACAGCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000078814-MYH7B:NM_020884:12
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.065 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=FE(4.4=100)
A:
NA
C2:
PF0006316=Myosin_head=FE(3.1=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGCACCCTTGAGGATCAAATCA
R:
AGCTGTCAATATCCGCGGATG
Band lengths:
157-276
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)