HsaINT0107894 @ hg19
Intron Retention
Gene
ENSG00000078814 | MYH7B
Description
myosin, heavy chain 7B, cardiac muscle, beta [Source:HGNC Symbol;Acc:15906]
Coordinates
chr20:33581949-33583381:+
Coord C1 exon
chr20:33581949-33582204
Coord A exon
chr20:33582205-33583138
Coord C2 exon
chr20:33583139-33583381
Length
934 bp
Sequences
Splice sites
5' ss Seq
GCTGTGAGT
5' ss Score
7.39
3' ss Seq
CCGTTCCGTGTGCCCTCCAGGAG
3' ss Score
9.51
Exon sequences
Seq C1 exon
GGATGCGCTGTTCACCATCCAGTGGAACATCCGTGCCTTCAATGCCGTCAAGAACTGGTCATGGATGAAGCTCTTTTTCAAGATGAAGCCGCTGCTGCGCTCGGCGCAGGCTGAGGAGGAGCTGGCGGCCCTGCGGGCAGAGCTGCGGGGGTTGCGAGGGGCGCTGGCTGCGGCCGAGGCCAAGCGCCAGGAACTGGAGGAGACGCACGTCAGCATCACCCAGGAGAAGAATGACCTGGCCCTGCAGCTGCAGGCT
Seq A exon
GTGAGTCAGGGTTCCCCTTGTGACCGGGCGTCCCCAGCCCCGAGTACCCCTGGCTGCTCTGAGGGATAGTACAGCGAGACCCATGGGGCTCAGGCCTTATGTCTCTCTGTTCCAAAGATGCCATGAGATGAGGCCTCCATGTCCCAGCCTCACCACCCCAAGGCCTCGTCTGGCACGTTTCCTGGCACTCTCCCCTCGTGCCACCTTGGCCTCCCGCTAAAGCAGAGGAACCCCAGCTCCCCAGCTCTCCCCTCCCTGCAATCCCTGAAACCAAACAGACCCATGCTCTCTTCTCTGGTTAAGGGCCATGGGAACCCAGGTGGCAGGTAACAGGGTGATAGCCAGAGAGCACAGATCAAAGGTCTGGAATCTCCCCAGGTCCACAGAGCAAGCTTTCCTGCCTTCGGCACATGGCTTTGTGTATCAATTGTGTGCCAGGCTCAGGCTAGTGCAGGAGGAACGTTGGTGGGAAGACAGAGATGGCCCTGTGGTCACAAAACTCACCTGCTAGTGCAGGAGACTGTGACGCAGCTGGACAGTAAGGAAATGGGGGGTAAGGATACCTGAGCCCTTCCAGGGACTGCCTCCAGGAGCCCGTCCGTGGCTGTGCAGAGGCTGCTGCTGCTCACCCTGCCCCTCGGAAGGCCTCAGCCCAACAGCGGGGCAGTGAGCAGCGGGCTTCCCTCTCAGAACCCTTGTTTGGGCCTCACTCTGGGCCGCCCCGCACTTCTAACTTTCCCCTCTTAATGCTCTGGTGTGTCCCTCTGCGCTATTGCCCTTCCATGCCCAAGAGCGAGTCAAGACATTCCTGAGTTCTCAGAGCACAGCCAAACTTTGCTACAGAGGCAGTTTCCTCTCCAGGGCCTGGCCTGGTGTCTCTCTGCTGGTTTACCTGGCCCTCCCCCAACCTGGCCCCGTTCCGTGTGCCCTCCAG
Seq C2 exon
GAGCAGGACAACCTGGCAGATGCCGAGGAGCGCTGCCACTTGCTGATCAAGTCCAAGGTGCAGCTGGAGGGGAAGGTGAAGGAGCTGAGTGAGCGGCTGGAGGATGAGGAGGAGGTGAACGCTGACCTGGCCGCCCGCCGGCGCAAGCTGGAGGACGAGTGCACGGAGCTCAAGAAGGACATTGATGACCTGAAGCTGACACTGGCCAAAGCTGAGAAGGAGAAGCAAGCCACTGAGAACAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000078814-MYH7B:NM_020884:27
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.035 A=NA C2=0.321
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=PU(24.0=62.8)
A:
NA
C2:
PF0157614=Myosin_tail_1=FE(35.6=100),PF045827=Reo_sigmaC=PU(50.4=81.5)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGGAACATCCGTGCCTTCAA
R:
CACCTCCTCCTCATCCTCCAG
Band lengths:
352-1286
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)