HsaINT0107898 @ hg19
Intron Retention
Gene
ENSG00000078814 | MYH7B
Description
myosin, heavy chain 7B, cardiac muscle, beta [Source:HGNC Symbol;Acc:15906]
Coordinates
chr20:33584416-33584976:+
Coord C1 exon
chr20:33584416-33584561
Coord A exon
chr20:33584562-33584885
Coord C2 exon
chr20:33584886-33584976
Length
324 bp
Sequences
Splice sites
5' ss Seq
GAAGTAGGT
5' ss Score
6.22
3' ss Seq
ACCCACTCTGTGGCTCCCAGGAA
3' ss Score
7.24
Exon sequences
Seq C1 exon
CTGGAATGCTCCCTGGAGCAGGAGAAGAAGCTGCGCATGGACACGGAGCGGGCCAAGCGCAAGCTGGAGGGTGACCTGAAGCTGACGCAGGAGTCGGTGGCTGATGCTGCTCAAGACAAGCAGCAGCTGGAGGAGAAGCTCAAGAA
Seq A exon
GTAGGTGTGGTGGGGCAGCAGGTGGGGGCCTTCTGAGCCTGCACCTGGCCCTTGTTCCCTTCTGGATTCTTGTGGTTCCTGCGGCATTGCAGAGGTTAAGGGTGGGGGTTGACAGATGGGGCACTGGGGTGCAGGGGTAGTGTCTTGCCCTCCCTGTACTGAGGGCCCTAGCCAGGGTCCAGGGCTGAGGCCTCAGGGCCCAGTGCAGCAGGTGCATGGGGTGAGGTCCCTCAGGGCCTGAAGGGGACTGGGGGGCGTTATGGGGTCCCAGGCGGGTGGGTGGGAGTTAAGGCCTGTGCTGGCCACCCACTCTGTGGCTCCCAG
Seq C2 exon
GAAGGACTCCGAGCTGAGCCAGCTGAGCCTGCGGGTGGAAGACGAGCAGCTCTTGGGGGCCCAGATGCAGAAGAAGATCAAGGAGCTGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000078814-MYH7B:NM_020884:30
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.918 A=NA C2=0.226
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=PD(12.9=59.2),PF045827=Reo_sigmaC=PD(3.1=8.2),PF0157614=Myosin_tail_1=PU(1.6=28.6)
A:
NA
C2:
PF0157614=Myosin_tail_1=FE(3.5=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGGAGCAGGAGAAGAAGCTG
R:
CAGCTCCTTGATCTTCTTCTGCA
Band lengths:
222-546
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)