HsaINT0107900 @ hg19
Intron Retention
Gene
ENSG00000078814 | MYH7B
Description
myosin, heavy chain 7B, cardiac muscle, beta [Source:HGNC Symbol;Acc:15906]
Coordinates
chr20:33585054-33586224:+
Coord C1 exon
chr20:33585054-33585443
Coord A exon
chr20:33585444-33586097
Coord C2 exon
chr20:33586098-33586224
Length
654 bp
Sequences
Splice sites
5' ss Seq
AAGGTGTCC
5' ss Score
3.24
3' ss Seq
CTCCCAACCTGGGATCCTAGGCC
3' ss Score
3.5
Exon sequences
Seq C1 exon
GCTCGGGCGGAGGAGCTGGAAGAGGAGCTGGAGGCAGAGCGGGCAGCCCGGGCCCGCGTGGAGAAGCAGCGTGCAGAGGCGGCGCGGGAGCTGGAGGAGCTGAGCGAGCGGCTGGAGGAGGCAGGCGGCGCATCCGCGGGGCAGCGCGAGGGCTGCCGCAAGCGGGAGGCGGAGCTGGGGAGGCTGCGGCGGGAGCTGGAGGAGGCGGCGCTGCGGCACGAGGCCACAGTGGCGGCACTGCGGCGCAAGCAGGCGGAGGGCGCGGCGGAGCTGGGGGAGCAGGTGGACAGCCTGCAGCGGGTGCGGCAGAAGCTGGAGAAGGAGAAGAGTGAGCTGCGCATGGAGGTGGACGACCTGGCTGCCAACGTGGAGACTCTGACCCGCGCCAAG
Seq A exon
GTGTCCGTGCCTTCCTCACCCCATACCCACCCTGACTTTAAACCAATCCCGATCCCAGCAGCCAATACTGTTCCCACACCAGCCTCCACCCAGTACCTTATCCTGAGCCCTGACCTCTTCACCTGGTACACAACCCTCATTTCTCAGCCTCCTACCAGTCCTGACCTTAAGCCGTGACTCCCAAGCCCTGTTCCCTGACTCCAGGTCATTTCTGATCCAGCATCTACTTCCAGCCTCAGACCCTTGAACCAGCAGTAGTTGTGACCCTAGCCCTTGACTCCTGAACTCTGACTTAATACCTGTCCTCTCTTCCTGTCCTGAACCCCAGCACCCTAGCCTTAACCCCTGACCTTTCTACCACATAATCCTGACAGCTGACCTCTGACCATTGTCCCCAGGTGACTCCGCAGCTACCATCCCAACTCTCACCCTGACCCACTGCCCTGGGACTGGCCCAGCCCTGTCAGTTCTGACACCTGTTAAGCCCAGCAGTAGAATCTCTTTCCCTGACTTTGAACTTGGGGCTCTGCTCTCCCTTTGATTCCTGGGCCCACATCTAGCTTACCAGTCTCTGATCCCAGATCCTGCCATCTGATGCACAAACTTGTTCTGACATCTAACTCCTGACCCCTGACTCCCAACCTGGGATCCTAG
Seq C2 exon
GCCAGTGCAGAGAAGCTGTGCCGGACCTATGAGGATCAGCTAAGCGAGGCCAAGATCAAGGTGGAGGAGCTGCAGCGGCAGCTGGCGGACGCAAGCACGCAGCGTGGGCGACTACAGACGGAAAGCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000078814-MYH7B:NM_020884:32
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.508 A=NA C2=0.326
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=FE(15.0=100),PF0003816=Filament=PU(11.7=24.6)
A:
NA
C2:
PF0157614=Myosin_tail_1=FE(4.9=100),PF0003816=Filament=FE(15.3=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTGGAGGAGCTGAGCGAG
R:
CTTGGCCTCGCTTAGCTGATC
Band lengths:
355-1009
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)