HsaINT0107905 @ hg19
Intron Retention
Gene
ENSG00000078814 | MYH7B
Description
myosin, heavy chain 7B, cardiac muscle, beta [Source:HGNC Symbol;Acc:15906]
Coordinates
chr20:33587374-33587709:+
Coord C1 exon
chr20:33587374-33587498
Coord A exon
chr20:33587499-33587593
Coord C2 exon
chr20:33587594-33587709
Length
95 bp
Sequences
Splice sites
5' ss Seq
GAGGTCAGG
5' ss Score
4.94
3' ss Seq
TGCCTGCTCTGTATCCACAGGGG
3' ss Score
10.6
Exon sequences
Seq C1 exon
AGGAGATCAGCGACCTCACAGACCAGGTGAGTCTCAGTGGGAAGAGCATCCAGGAACTGGAGAAAACCAAGAAGGCGCTGGAAGGCGAGAAGAGTGAGATCCAGGCTGCACTGGAGGAGGCAGAG
Seq A exon
GTCAGGGGCTGGCTGCAGGGGTGGGTGGACACTGACCTGCTGCTCCACTGGCCATCCCCCCCCCCCACCCTACCCTGCCTGCTCTGTATCCACAG
Seq C2 exon
GGGGCCCTGGAGCTGGAGGAGACCAAGACGCTGCGGATCCAGCTGGAGCTCTCCCAGGTCAAAGCAGAAGTGGACCGGAAGCTGGCAGAGAAAGACGAGGAGTGCGCTAACCTGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000078814-MYH7B:NM_020884:37
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.810 A=NA C2=0.359
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=FE(4.8=100),PF045827=Reo_sigmaC=FE(27.2=100)
A:
NA
C2:
PF0157614=Myosin_tail_1=FE(4.4=100),PF045827=Reo_sigmaC=PD(3.3=12.8)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAAACCAAGAAGGCGCTGGAA
R:
GCACTCCTCGTCTTTCTCTGC
Band lengths:
168-263
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)