HsaINT0107916 @ hg19
Intron Retention
Gene
ENSG00000078814 | MYH7B
Description
myosin, heavy chain 7B, cardiac muscle, beta [Source:HGNC Symbol;Acc:15906]
Coordinates
chr20:33567464-33568537:+
Coord C1 exon
chr20:33567464-33567607
Coord A exon
chr20:33567608-33568380
Coord C2 exon
chr20:33568381-33568537
Length
773 bp
Sequences
Splice sites
5' ss Seq
TATGTGAGC
5' ss Score
2.97
3' ss Seq
TACCTATACTCTCTCTTCAGACC
3' ss Score
8.98
Exon sequences
Seq C1 exon
GTGCTGATGGTGCGTGAAGCCGAGCTGCAGCCCATGAACCCGCCTCGCTTCGACTTACTGGAGGACATGGCCATGATGACGCACCTGAACGAGGCCTCTGTGCTGCACAACCTGCGCCAGCGCTATGCCCGCTGGATGATCTAT
Seq A exon
GTGAGCCCCAGGCCCGGGCCATGGGCGGGGTGGGGCTTGTATGTGGGGCGGGGCTAGAGATGAGGTGCTGGGGGCGGGCCCATAGCGGTGGGGCGGGGCTGTGAGCGGTGGATCGGGGCTGTGAATGATAGAGCGGGTCCATAGCGGGGGTGGGGCTGTGAGCGATGAGGCGGGGCTCTGAGCAGTGGGGGCGGGGCTGGAGGTTGGGCCTTGGGACCTTAGGGGAGCAGCTGTAGCAGTGCGGGGCGGGTCTAGAACTCACCTGCGGACTATGGAGGCCGTGCGTGTGGGCTGGGGCAGGGCTGTGAGCACAAGTCAGGGGTGAGGCCAGGACGGCCACAGAGGGTGTGGTGTGGCAAGTCAAGTAGCTCCTTGAGGAATATCGCAGGGTTCTTCTGAAGACTGGGGCCTGGGGCCTGGGGATGGGAACTTGCGTATCCCTCCCAAAACCCTACCTATGGGGGGAGAATGTGGTGGCCCATGCCTGTAATCCCAGCACTTTGGGAGGGCAAGGCGGGCGGATCACCTGACGTCAGAAGTTCGAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTGTACTAAAAATACAAAAATTAGCCGGTCGTGGTGGCACGCGCTTGTAGTCCTAGCTACCCTGGGAGGCTGAGGCAGGACCCAGGAGGCGGAGGTTGCGGTGAGCCGAGATCATGCCGTTGTACTCCAGCCTGGGAGACAGAGCAAGACTCCATCTCAAAAACAACAACATAAACCCTACCTATACTCTCTCTTCAG
Seq C2 exon
ACCTACTCAGGCCTCTTCTGTGTCACCATCAACCCCTACAAATGGCTCCCAGTCTATACGGCCTCCGTAGTGGCTGCTTACAAGGGAAAGCGCCGCTCAGATTCCCCGCCCCATATATATGCGGTGGCGGACAACGCCTACAACGACATGCTGCGCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000078814-MYH7B:NM_020884:7
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.042 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0273614=Myosin_N=PD(16.3=14.6),PF0006316=Myosin_head=PU(4.1=58.3)
A:
NA
C2:
PF0006316=Myosin_head=FE(7.6=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGCTGATGGTGCGTGAAG
R:
AGCATGTCGTTGTAGGCGTTG
Band lengths:
296-1069
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)