HsaINT0108187 @ hg19
Intron Retention
Gene
ENSG00000145555 | MYO10
Description
myosin X [Source:HGNC Symbol;Acc:7593]
Coordinates
chr5:16670635-16671651:-
Coord C1 exon
chr5:16671531-16671651
Coord A exon
chr5:16671088-16671530
Coord C2 exon
chr5:16670635-16671087
Length
443 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAAA
5' ss Score
8.59
3' ss Seq
TGTTGACTGTCTCCTTTCAGGCC
3' ss Score
11.63
Exon sequences
Seq C1 exon
GCTGGCTGCCACATCCGAGGTTGGGGACCTGCCATGGAAATTCTACTTCAAACTTTACTGCTTCCTGGACACAGACAACGTGCCAAAAGACAGTGTGGAGTTTGCATTTATGTTTGAACAG
Seq A exon
GTAAAAGGAATAGTTAGAAACAGATTTCTTTGCCGGCAAGCAAGGGTGAAACCTGTTAATACTTAGCCTTGTAAGTTAACTGGTACTTAGAAATGAGGCACACCTGTGGATTTCCCAGCAAAGACAAGACCAGCTGCTCTTTCATTCGTTTGTAGAATGAAACCTGCTACACATTTTATTTGAACCTCCGTTCCAGGGACTGTTCTAGTTGACAGGAGAGAGAGCACAAGGAATAAAATATGTGACGTGTGTTAGATGGTATCTGTGCTAGGGAGAAAATTAAATTTAAAGCAGTGAGCCAGGGGTGAGGGTACAGTTTTAGCCAGGGCAGTCAGGGAAGGTGAGTTTGAGAGAAACCCTCATGAAGTGAGGGAGCAAGCGACGTGGGCATCCCATGGCATGGCAGTGCGTTGACCGGAAAGCTGTTGACTGTCTCCTTTCAG
Seq C2 exon
GCCCACGAAGCGGTTATCCATGGCCACCATCCAGCCCCGGAAGAAAACCTCCAGGTTCTTGCTGCCCTGCGACTCCAGTATCTGCAGGGGGATTATACTCTGCACGCTGCCATCCCACCTCTCGAAGAGGTTTATTCCCTGCAGAGACTCAAGGCCCGCATCAGCCAGTCAACCAAAACCTTCACCCCTTGTGAACGGCTGGAGAAGAGGCGGACGAGCTTCCTAGAGGGGACCCTGAGGCGGAGCTTCCGGACAGGATCCGTGGTCCGGCAGAAGGTCGAGGAGGAGCAGATGCTGGACATGTGGATTAAGGAAGAAGTCTCCTCTGCTCGAGCCAGTATCATTGACAAGTGGAGGAAATTTCAGGGAATGAACCAGGAACAGGCCATGGCCAAGTACATGGCCTTGATCAAGGAGTGGCCTGGCTATGGCTCGACGCTGTTTGATGTGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000145555-MYO10:NM_012334:38
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.007
Domain overlap (PFAM):
C1:
PF0078818=RA=PD(0.1=0.0),PF0037313=FERM_M=PU(9.7=39.0)
A:
NA
C2:
PF0037313=FERM_M=PD(89.1=97.4)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGTGCCAAAAGACAGTGTGGA
R:
ATCCACATGTCCAGCATCTGC
Band lengths:
351-794
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)