HsaINT0108458 @ hg19
Intron Retention
Gene
ENSG00000141140 | MYO19
Description
myosin XIX [Source:HGNC Symbol;Acc:26234]
Coordinates
chr17:34883895-34888511:-
Coord C1 exon
chr17:34888357-34888511
Coord A exon
chr17:34884034-34888356
Coord C2 exon
chr17:34883895-34884033
Length
4323 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAAA
5' ss Score
8.59
3' ss Seq
CTTCACGTTATCTCTTCCAGGTC
3' ss Score
10.74
Exon sequences
Seq C1 exon
GCGCTGGAGTGACTTGTCTGAGATTCCTCCAGAACTGAGCCCTTTGTTGGAACCATACCCCAGCCCATGGTCCCATGACTAGGTGGATAGTACTCCTTGTACCTCCTGCAACCCAGAACCCTGGCTGACCACTTTGAAGGAGGATGCTCCAGCAG
Seq A exon
GTAAAACCTCAACCTTAGATAACCCAGGCCCTCAAGCACCTGCAGCATCTGTTGCTAGCCCTAACCTGGAAGGAAGGGAAAGCCCCCTTAAAGGTCTCTTTTCTCTCCTCAAATTGTCTCTCCAGTGCCTTTTACTCATCATCAAGAAACTCTTCCTGATACCTAATTTGAATCTGTCTTGTGGTTTTTAGCTCCTTTCTTTGGGATAGGTAAGGTGGGATGGGTAAGGGAATCCTTAGGGCACTTTGGGGATTCTGCAGAGGAAGTCCTGAGAGATGTCCCTGCCACCTGAATTGTTGAGGCATAGTAGAAGCCTGGGGCTTCCAAGAGGATGTGTTCCTTGAAGCTAAGCCTTAAAGAACTAGAAAGAATTAGCCACTTGGAGAAGGAAAATAAGCACTCCAGGCAAAGAGGTCAGCCTGTGCAGAAATGTAGGAGACTATGAGGAAATATAGAAGGATTCTAATGAGTGGATCATGGGTTACATGATCCCCATGTCTCTGCCTCTCTGAAAAGGCTACTGTTGCCCCAGGCCTGTAGGATTCCAAATCACCTTTTACAGCGGAGCTCTCTCTCATACCCATATCATCCTTCATGTGTAACTCTTGGTCCTGAGAGAGTGCCAGTACTTATTTGCTGACTTTTTATTTTACCAAGTGTTGCCAGGCACTGGGCTGAGGCAGATGTTGAGGTTGGTGCTTGCCCTCAAGGAGCTCAGAGTCTAGTGGAGTCTTGGGTAGGTAAGTGCCTGACATCAGCAAGGTAGCAGCCAGGTGTGGGGCCTGCCAGCATCAAGGGAGCCATAGTAGACACTGCAGCTTGACCTTCCAGCCATATGGCTCCTGGAACAGGTTTGAAGGTAAGAAGTGGGCAAAACAGTTGACTGCTCTGGGCTTTTTTCTTGCTTATTTTTAAACTTTTTTTTTCTCTTATTAAAAAAAAGGTATATCAATACAATGGAATAAAGCAAGTTACACAAAAATATAATACTTTTCAATGTTTTTAAAGTATGTAGGGGAAAAAACCTATGATATTCTCTAAAATATTGGTTATTTCTGGGTAGTATGATTATGGATTTTTATGCTCCTTTTGCTTATCTCTATTTTCCAATTTTTTTTTTTTTTTTTTTTTGAGATGGAGTCTCACCCTGTCATCCAGGCTGGAGTGTAGTGGCTTGATCTTGGCTCACTGCAATCTCTGCCTCCCAGGTTCATGCTATTCTCCTGCCTCAGCCTCCCGAGTAGTTGGGACTACTGGTGCTGGCCACCACGCCTGGCTAATTTTTTGTATTTTTTAGTAGAGATGGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCACCCACCTCGGCCTCCCAAAGTGCTGGGACTACAGGCGTGAGCCACCGCGCCCAGCCTCCAAATTTTTTTTAATAATTTTTGTTTATTTATTTTTATTTTAGAGATGGAGTCTCACTCTGTAGACAAGGCTGGTCTCAAACTCCTGACCTCAAGTGATCCGTCTGCCTCAGCCTCCCAAAGTGCTTTTACAGGGGTGAGCCACCGCACCCAGCCGTGAGACCCTGTCTCTTAAATAAATAAATAAATAAGGCCAGGCACGGTGGCTCATGCCTGTAATCCCAATACTTTGGGAGGTCGAGGCGGGCAGATCACCTGAGGCCAGGAGTTCAAGACCAGTCTGGCCAACATGGCAAAACCCCATTTCTACTAAAAATACAAAAACTAGCCAGGTATGGTGGTGCATGCCTGTGATCCCAGTTACTTGGGTGGCTGAGGCATGAGAATCACTTGAACCTGGGAGACAGTGGTTGCAGTGAGCCGAGATTGTGCCACTGCACTCCAGCCTGGGCGATAGAGCGAGACTCTGTGTCAAAAAAAAAAAAAAATACAAAAGCCACTTTTACGCGTGCCTGTAGTCCCAGCTACACAGGAGGCTGAGGCAGGAGAATGGCGTGAACCCGGGAGGCGGAGCTTGCAGTGAGTCGAGATCGCGCCACTGCACTCCAGCCTGGGCGACAGAGCGAAACTCCGTCTCAAAAAAAAAAAAAAAAAAAAAAAGCCACTTTTAGAAGAAGAATAGCTAACCCCTTTTGGCAGATTCCAGATGGCCTTTCTAAATCCTTCGTGTGTTTTTGTGCTTGTGAGTATCTGTGAGGTAGGTACCATTATCCCATTTTACAGAAAAGAACTTTAAATAATTATTTAGAGACAGGGTCTCACTTTGTTGCCCAGTGCAGTGATATCCCCATAGCTCACTGTAGCCTCGACCTCCTGGGCTGAAGCAACCCTCCTGCCTCAGCCTCTAGAATAGCTGGGGTTACAGGCACATGCCATAATGCCCAGCTAATTTTTAAATATTTTTTATAGAGACAGGGTCACCTTGGCCTCCCTAAGTGCTGGGATTACAGGCTTAAGCCACTATGGCCAGCTGGAAATTTTTCTATTTTTATTTTTTACTTTAGAGACAAGGTCTTGCTCTGTTGGCCAGGCTAGAGTGCAGCGGTACAATCATAACTCATTGCAGCCTCGAACTTTTAGGCCCAAGTGGTTCTTCTACCTAAGCCTCCCAAGTAGCTGGGATTACAGGGACCAGATGAGGAGAATTGAGGCAGAAAGAGATTAAGAAATTAACATAAGAGTATATAACTGTAAGAGATAGAGTCAGGATTCAGAGCCAGACAACTAACTTTCAAGTCCAGGTACTTGATCACTATACTCAGATGCCTCTCTGGTTGGATCAGAACTCTTCATAAATTGTGTCTGTGTTTGTGAATGGTTTGTGTAGTGGTGGTTTTTTTTTCCCCTTCATAAAAGGAGAGGGATATGCATAGATATAGCTGTGCTCTGACCTCCGCAGTTACTCTGGAGGCCAAGAGCCTACCTTGTGCATTATAGTGGGCCCAAAGTTCAGAGAACAGGCAACAGTTTTGGAAGAAATGCATTACTGGGCCTCTTGGAGGAAATTTGCCACCATGGCTTATTTCTATGAGAGATTTGAAATTTTAGGCTCACCATTCTCATTGGAAATTCACCTGTTGTATCACAGACCTCTTCCTTCAAAAGCACATTTCAGCAAGATACCTGTCTTCAACCCCCACTCTGTCTTTCCTGCATCCCCAAAGGAGACAGTAGGAGAAATGGGACCACAGGAGGAAGTGGAGGGATGATACATCAAGAATGGGCAAAGGAAGATAGGGTGACTCATGCCTCTAGTCCCAATTACTCAGGAAGCTGAGGCAGAAGGATCACTTGAGCTCAGGAGTTGGAGGCTGCAGTGAGATATGATCATGCCACTGCACTGCAGCCTGGGTAGCAGAGCAAGACTCCATCTCTTAAAAAAGAAAGGAAAAAAAAAAGATAGGCAAGGGAGGAGAAAGGACCTGTTCCCTTGGTGCTTATTCTTGACCTCAGACAGCCGTCTGAGCCAGGCTTTCTCTCAAGCAGACTCGGGCCAAGGGAACCAATTCATTAGCCAGCCTAAATTTAAGCCACAAAAGGCAGGTGATGAAGACATGGGGCTACCTCTCTCAGAAGGTACAGCTGTTTTACATCAAAAGCTGAACTGTCTCTTCCCAAAAAGGCCTAACCCATGGTTCTTTTCCTTTGCAACATTCCTATAGCCTTATTTCTAATAAGGCTAGTAGCCTGGAAGTGCTACTTGCAAGTGGCCGGAGCTCTTGGCAGAAGAGATAGCATTTGTTGAGTACATGCTGTATGCCGGGCACTGACTAAATGCTTTGTATATCTCTTCTTTTCTTCCCAATAACCTTGTCAGTTGAGTTTATTTTCCTTTATTTACGAATAAACAAACTGTGACTCAAAGAGGGTAACTTACCCAGGCTCACAGGGCTACTAAGAGGCAGAACTGAAATTTGAACCCAACCAGACTATGATACCAGAGTCTCCTTCTACTATACAGGTTCCCACCCTTCTGTAGCTGCCAGCTGTTTTGAGTACCAGCTGTCGCGGCCTTCATGTTTTTTGGTTTTTTTTTTTTTTGAGACAGAGTCTTGCTCTGTCGCCCAGGCTGGAGTGCAGTAGCACAATGTTGGCTCACTGCAAGCTCCGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTTCCGAGTAGCTGGGACTACAGGTGCCCGCCACCATGCCTGGCTAATTTTTTGAATTTTTTTTAGTAGAGACGGGGTTTCACCGTGTTAACCAGGATGGTCTCGATCTCCTCACTTTGTGTCCTGCCCGCCTTGGCCTCCCAGAGTGCTGGGATTATAGGCATGAGCCACTGTGCCTGGCCTCACCTTCACGTTATCTCTTCCAG
Seq C2 exon
GTCAATGGCCACAATCCGGGGTCTGATGGCCAAGCCAGGGAGTACCTCAGAGAAGACCTGCAGGAGTTCCTGGGTGGGGAGGTCCTGCTGTACAAACTGGATGACCTCACCAGGGTGAATCCTGTGACACTAGAGACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000141140-MYO19:NM_025109:4
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.833 A=NA C2=0.281
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=PU(1.1=50.0)
A:
NA
C2:
PF0006316=Myosin_head=PU(11.2=29.8)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)