HsaINT0108725 @ hg19
Intron Retention
Gene
ENSG00000071909 | MYO3B
Description
myosin IIIB [Source:HGNC Symbol;Acc:15576]
Coordinates
chr2:171259358-171260910:+
Coord C1 exon
chr2:171259358-171259505
Coord A exon
chr2:171259506-171260756
Coord C2 exon
chr2:171260757-171260910
Length
1251 bp
Sequences
Splice sites
5' ss Seq
CAGGTAATA
5' ss Score
8.55
3' ss Seq
CACAATCCATTTCCCTCCAGATG
3' ss Score
9.42
Exon sequences
Seq C1 exon
TAGTGCAGGAGGTGGAATGAATGTGGGGATCTTGGATATCTTTGGATTCGAGAATTTTCAGAGAAATTCATTTGAGCAGCTCTGCATAAACATCGCCAATGAGCAAATCCAGTACTATTTCAATCAGCATGTTTTTGCTCTTGAGCAG
Seq A exon
GTAATAGTGAACTCTGAGGTAACTAAACTTGATGGGGAAAAGGTGTCTCCAAGCTGCCCACAATTTGTAGCAGAAACCCTGTAGACTAACAACTAAAAGACCCTAGAGAGAAAATAGGGTAAGGCAGTCCTGGCTAAATAGTCTAAATTTGTCTGGAAAAGGTCTCGATTTCTGTGGAAAGGTACATTTCCTCACTTGAGTGGAGCTGGTGACAAGTCACTCATTTAAATTTTGTGTCAAAACTCTTTCGTGCATATTGCTCAAAATACTGTATCTCTTCTACTTTATTTAACTAAAAATATTTATGATTGCGTTCAAAATGACACAGATGACCTTGAATTCGGGACATAGGTTCTTAACTGCTACACTAGCCCTCCCTATCCCCTATCTGCTATATACCAGATCCCACAGTCACTGGAGAGGTATCTCCAGGGAAGAGTAAGATGTGTTCTTGGTTTTCTAGAAATGGAAATCATCCCTCTATGAGTTTAATAATAAATAAGACAGAGTAAGAAACTAGTGGACCCAAGGGATGGGGCTCTTTTCCTGTGGCAGCAGCCTATATAGCAGTCTGATCAACCCCAACCTTTACTTAAACCTTAAGACTCTCTTCTGTATGAAGTAGTTGCAATAATGAAACATTCTGGCTAAGCCTCTTCGATGCAGGGATAATTGTTTTAATGCAGGCATGAGGACGCACAAACTCAACTTCGATGAGATAGACACAAAGACATTTAGTGAAAATACCAGCATTGCTTTTATCTCTGGAGCTGGATAAATCTGTATAGCACTCCTCTCCCATCCACTCTTGTTTCAGTCCAGGTTCCTTCCATTTATTTCCCGGTAATCTGGAGTTTTTCTAGTTTTCCAACCCTAGATGATTCCTTTGTCGAACTCCTTGCAGAAGAGAAGTCTGTTTTCTTGGTTTAAACAATATTTCTCACCAAAATAAATTTTTTTTTTCAGCTTCACTTCCTTGTACATTAGTTTCTAAATGATAAGTTACCAAGTCCACATTTGAGAGAGATGTTTTACTGGTTTAGCTGCTGCCATAGGCCACTTGTAAGTCAGATTTAAGTGCACAGCTTTAATGGTGTTATATGCAGAAGATTCCTTTATTATACACATAAAACATATCCTGCTTTCCACATGCATTCAATGTTGCTAGACCCAGAAAGTCCATGTCAAAGTATCCTGGTGGTCCCAAGGCTAGTTTTGGGCTGGAGAGAATCACAATCCATTTCCCTCCAG
Seq C2 exon
ATGGAATATCAGAATGAAGGCATTGATGCTGTACCCGTGGAATATGAGGACAACCGCCCGCTCTTGGACATGTTCCTCCAGAAACCCCTGGGACTGCTTGCACTTTTGGATGAGGAAAGTCGGTTTCCCCAAGCAACTGACCAGACCCTGGTTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000071909-MYO3B:NM_001083615:19
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=FE(7.0=100)
A:
NA
C2:
PF0006316=Myosin_head=FE(7.3=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGCAGGAGGTGGAATGAATGT
R:
CAGGGTCTGGTCAGTTGCTTG
Band lengths:
296-1547
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)