HsaINT0108760 @ hg19
Intron Retention
Gene
ENSG00000197535 | MYO5A
Description
myosin VA (heavy chain 12, myoxin) [Source:HGNC Symbol;Acc:7602]
Coordinates
chr15:52671822-52672105:-
Coord C1 exon
chr15:52672019-52672105
Coord A exon
chr15:52671931-52672018
Coord C2 exon
chr15:52671822-52671930
Length
88 bp
Sequences
Splice sites
5' ss Seq
ACGGTGAGC
5' ss Score
9.44
3' ss Seq
AGATGGTTTTCTTTTAATAGGTG
3' ss Score
7.56
Exon sequences
Seq C1 exon
GTTTGATGAGAAGAGGGCAGTGCAGCAGCTGAGAGCATGTGGTGTCCTGGAAACCATCCGAATCAGTGCGGCCGGTTTCCCCTCACG
Seq A exon
GTGAGCCTGGCATTTTTCAGATGTAAGGGATCCTAATGGGAGAAGATCCTAGTTCTTTAAGTAAACTCAGATGGTTTTCTTTTAATAG
Seq C2 exon
GTGGACTTACCAAGAATTTTTCAGCCGCTACCGTGTCCTAATGAAGCAGAAAGATGTGCTGAGTGACAGAAAGCAAACATGCAAGAATGTGTTAGAGAAACTGATACTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197535-MYO5A:NM_000259:17
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=FE(4.3=100)
A:
NA
C2:
PF0006316=Myosin_head=FE(5.3=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTGATGAGAAGAGGGCAGTGC
R:
GCATGTTTGCTTTCTGTCACTCA
Band lengths:
167-255
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)