HsaINT0108781 @ hg38
Intron Retention
Gene
ENSG00000197535 | MYO5A
Description
myosin VA [Source:HGNC Symbol;Acc:HGNC:7602]
Coordinates
chr15:52321359-52323444:-
Coord C1 exon
chr15:52323355-52323444
Coord A exon
chr15:52321510-52323354
Coord C2 exon
chr15:52321359-52321509
Length
1845 bp
Sequences
Splice sites
5' ss Seq
GAGGTGAGA
5' ss Score
7.66
3' ss Seq
ACTTTGCCTTATGACTCTAGGGC
3' ss Score
7.61
Exon sequences
Seq C1 exon
AAAAGAGGTGATGATTTTGAAACCGTCTCCTTCTGGCTCTCTAACACATGCCGATTTTTGCACTGCTTGAAACAGTACAGTGGAGAAGAG
Seq A exon
GTGAGAAAACCTTGATTACAAAACCAGCATGCTATACTTTCTCTGACCTTTTTAAGGAAAAAATGTAAAAGCACAAAATGTTTAACCATTTATTTAGGAACCCAAATTCAGAGGTGGCTTGGAAGTTCTTGCTTTGTTTGATGTTCACTATCTATGAAGCAGTGATTTGGAGAATGACAGTTTCTTCTTTACATTGTGAGAAAGCATAGAGAAAAATAAAATAAGCATTGGTCAGTGAATAGTTACCAGAAGTAAAACTTTTTGTCAGTATGTTTTAGTGGGCATTTCAAGAGCTAATATCAGAATAGTGAACTATTTAAAGAAATTAATCAATTTTGGCTTGCCACAATACATTAAAAGGTGATCAAAAATCGGGGGGAGGGATGGCATTGGGAGATATACCTAATGTTAAATGATGAGTTAATGGATGCAGCACACCAACATGGCACATGTATGCATATGTAACTAACCTGCACATTGTGCACATGTACCCTAAAACTTAAAGTTTAAAAAAAAAAAAGAAAATTTTAATATTAATACTCTTGGACAATAAGAGGACCTTAAAATCCTTTAACTCTAAAAAAAAAAAGGGTGATCAAAAATCATGTCTTTCGATTTGTCCAAAAAAACTCTATTGTTTTTGTTTGTGGGGATATGTTCATTAGTTGTTTGATAGACTTCAAATATTTCAAAACTATGTAGAATATTAATAATGACTATTAAGGGCTGCTTTAGTATGTGTCAGACAGCACTTACTGTATATGGTGTTATTTATGATCATTAATTCTTACAGCATCTCTGTGAGGTAGGAATTATAGTCCAGTTTTACAGATGAGGAAGCCAAGGCTCACTGGGGCTCATTGATTTACCCAAGTTCTCTTGGCCACAAGGAGCAGAGCTGGGATCCTGGGTCTGGCACCGCTGAGGGCCCATGACCCTAGCCAACTGCCCTCCATGCCTCCCATCCCTTTGCCAGGAGGGCAGCAGAGAAGGTGCCCAGCGGCACTTCCTGAGCACTGACAGGCAGATGATGGGAAACACAGAGATGAGCAAGGCCTAGTCCCTGAGAAGATGGGGCCAACAGACCAGAATCCCTCAGAGGGGTCGTTGACTGCATCCTATCAGTCCCCACTTTCGGACCAGTCATTAAGTAGGTGGTAAGGAGGCAGATGCTTGGCTGTAGGGAGAATCCTCAGAGTAAGCACTTGCCTTTATCACGTAGCATCAGGCAAACAACGTGTTAAACTGCAAAGTGACTGGAAGAAGTGCCGCCCATTCAGTTCCATTTTAACAGATACCACCAAAGATTCCCTTCTAACCTCTGACTGAAAACCATGGTGTGGGTACTACGAAATAGAGTAAAGAGAACTTTTTGTATGTATTCACTAGTCTCTGTAGAAATCGGTCTATTTCAAGATTATATATGTCCTTTGGGTGTAGTTTTTAAGAATAGGACTATAAAGAACTGAAGTTAAGAGATAATTTAGATAATTTAGTGTTTGACAGTAAACCTGCTGTTTCAGAAGTGAAACACTCTATTTTTTTTTTTTTTTTTTTTTTTTAGTTAAGTTCCTCCAATTTGCTTCATTGACATTGCTATTGGGAAGACTTAAATGCTAGGTTGCCAAGTTAAGGTATTGTTCAAAAGCTAGTAAGAACTGGAGGGGGTTATGATGGAAGCAAACAAACACACATCAGCATTTGAGAATGTCAGTCCTGGCATTAGTGGGGAAGCTCCTTGGACAGAGCAGAAAAGAGCATGAAGATGCTGATCAAATTGGAGATAGTTAAACTGAAGAGACAGGTTACTTCATGTGTATCATTAACTTTGCCTTATGACTCTAG
Seq C2 exon
GGCTTTATGAAGCACAACACATCTCGCCAGAATGAACACTGCCTCACCAATTTTGACCTGGCTGAGTATCGGCAGGTGCTGAGTGACTTGGCCATTCAGATCTACCAGCAGCTCGTGCGGGTGTTAGAGAACATCCTTCAGCCAATGATTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197535:ENST00000399231:36
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.045
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGAGGTGATGATTTTGAAACCGTCT
R:
CAATCATTGGCTGAAGGATGTTCT
Band lengths:
238-2083
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development