HsaINT0108784 @ hg19
Intron Retention
Gene
ENSG00000197535 | MYO5A
Description
myosin VA (heavy chain 12, myoxin) [Source:HGNC Symbol;Acc:7602]
Coordinates
chr15:52606320-52609419:-
Coord C1 exon
chr15:52609245-52609419
Coord A exon
chr15:52606401-52609244
Coord C2 exon
chr15:52606320-52606400
Length
2844 bp
Sequences
Splice sites
5' ss Seq
CAGGTAGAG
5' ss Score
7.1
3' ss Seq
GATCATTTCATTTCTCACAGATT
3' ss Score
8.58
Exon sequences
Seq C1 exon
GTACAATGTCAGTCAACTGGAAGAATGGCTGCGTGACAAGAATCTGATGAATAGTGGGGCTAAAGAAACCCTGGAACCTCTCATTCAGGCTGCTCAACTTTTGCAAGTGAAAAAGAAAACAGATGATGATGCAGAAGCCATTTGTTCTATGTGCAATGCTTTAACTACTGCCCAG
Seq A exon
GTAGAGCAACTTTCCCTGTTACAAAATAATTTAACATTCATCAAAGATGATCTTTAGGGAAGTAAAGAAGTCCTCTACTTATTGCTTGTATCTCTGAGCTGACTTCATCTGTGTTCAAGAAGATATATGCCTCTACCAATCTTAAAGCAAGGAGATTTTGCCAGAAATTAATACATTTCAGTGCTAATTACAGTATAAATATATTTAATATTCAGCAAATATTTATTGAGTACTTACAGTGTTCTATATAACATTGAAGGCACTGGGATACACCCATAGGCAAAACAAAGTCTCTGCTCTCATGGAGTATACAGTCTATGCAGCTTATATTCCATAAAATAGCTTTCTATCTTATTTGATAATTGAGTGGATTATCAAATAGTGACTTTGTTTTTAGAGACAGATAATTCTTGTTACTTCAACAGATGATTAATTAAGCCTCCATCTCAAGGCACCATATTTATTGCTGGGGAAGATGCTTCAATAAATAAGGAAAAATTCCTGCCTTCAAGGAGCTTACAGTTCAGTAGGGAAGACAGAGTCGTATCCAACTGACTCTACCGTAGAGGTTCTAGCAAATTCTGTAGTAAGATGCCTAAAGGAAGTACTGAGGGAAGATAGCAGTATTCAGGGAAGGTCCCATTAATCTGGGCATTGAATTTAAGGAAGTGGAAGAATGAGAAGGGCATTTGAGGATTATAGTGACAGCATGAAGCAAGGCACAGGCATGAACATGCCCAATTTTCTTTTGCCCGGTTATTTTCTGTGCTGACTCTTAGACTTTCTTTCTTTTTTTTTTTTTTTTTTTTTTTTTGTGACGGAGTCTCGCTGTGTCGCCCAGGTTGGAGTGCAGTGGTATGATCTCCACTCACTGCAAGCTCCCCCTCCCAGGTTCACGCCATTCTCCTGCCTCAGCCTCTGGAGTAGCTGGGACTACAGGCACCTGCCACCACGCCTGGCTAATTTTTTGTATTTTTAGTAAAGATGGGGTTTCACCATGTTAACCAGGATGGTCTCGATCTCCTGACCTCATGATCCACCCGCCTCAGCCTCCCAAAGTGTTGGGATTACAGGCGTGAGCCACAGTGCCCAGCCAACTTTCTTAATGTTCATCATATATCCTACAACATATGAAATTTTCAGTTTTGCCCAATACAATTAAAACTCAATCAGTTTGAGACCAGCCTGACCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCCGGGCATGGTGGCAGGCACCTGTAATCCCAGCTACTCTGGAGGCTGAGGCAGGAGAATTGCTGGAACCTGGGAGACGGAGGTTGCAGTGAGCCAAGATTGCACCACTGCACTCCAGCCTGGGCAACAGAAAAAATCAGTAGGCCAGGCGTGCTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCTGAGGCAGACAGATCACCTGAGGTCAGGAGTTCAAGACCAGCCAGGCCAACATGGTGAAACCCCATCTCTACAAAAATACAAAAATTAGCCAGGCATTGTGGCGGGTGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATGACTTGAACCTGGGAGGCAGAAGTGGCAGTGAGCCAAGATTGTGCCACTGCACAGAGACTTCATCTCAAAAAAAAAAAAAGTCAATCAGTAGACAATCAGAATCAAGACTTGCAGCTTCTTAATGTTGAATTCATGTTTGCATAACTTCTTACTAAGAATAAAGCAGAACTATCTGACAGAACAATGGTCCTGAGATTTCCTCCCAGTTTCTGCAAGTGTGGAAAGTAAGAATACCCTGGAGGAAGCCCAACTTTATAGAAGTTGGCTGCCATTCAACTTCTAAAGAATATACTTTAATACTTAAATATACTTTAAGCATATTTCACAGAGTGAGGCAGACCTGCAGTTTATTTATTTAGCAAATATTAGTTAACAAAGTGGTCCCACTTTTTAAAATTCAAATACTTGCCTCCGAGAGACTGATCCCTAATTCAGTTTGTCACCCACAGACCTGATAACAACATGCCCACTTTCTAGTTCTCTGGTGCTTAATTTATTTTCCTATAGATCAGCACTGTCCTGCATTCAACTTTTATTTTCATTTTGTGTTAATAGCCACATGTGGCTAGTGACTACTACTGTTGTATTGGACAGCACAGGTTTAGACAATACCTTGAAAATGGAAATATCTACCTTATATAGACGATGATTTATTTTCATTAGAAAAGAGACATGACCATTTTACAAAAAAAAATTATTGAACTTTTTAAAAAAGAACTTCATACTCTCTAATTGATTAATTTCTTTAGGGGCTTTTGTTATTCATGTTATTTATGATCTTTTATAAAAATATGATTTAAAAAACATTCAAAAGAGATAATTGTATTAATACGGCTAACATTTTTATATGGAGAAAAGTTGCAGAATAGTATTAATAGAATGAATCCCATTTGTATAAAAATAAAATGAACTAGAATATTTATAGCAGCTAGAGGGGGTGTTCAGGACATGGTTAACAATTGCCACTTTGGGAGACTGGAAGGATGGAAGTGCGGACATTTATTTTTCATGTTTTATTCTCTTGTGCTATTTGAATATCTTCGAAATTTACACAGCTTCTTACAATATTACACAAACATTACATTGATACATTCTCTTGTAAAAATTCAGATAAAGGTAAATGTGCAGACCAGCTCCTCCTTCCTTCTGGTCCCAGCCCACCCCTGAGTAGAACTGAAATCTGTACGCACAGATCCTTTTAATTTTCCAGATTATAGGTACCCAGTGTGTATTTGATAATATGCCAAAAACTTTGATCATTTCATTTCTCACAG
Seq C2 exon
ATTGTGAAAGTGTTGAATTTGTATACTCCAGTTAATGAGTTTGAAGAAAGAGTCTCTGTGTCGTTCATTCGTACTATACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197535-MYO5A:NM_000259:39
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0184314=DIL=FE(54.7=100),PF0146614=Skp1=PU(69.3=88.1)
A:
NA
C2:
PF0184314=DIL=PD(12.3=48.1),PF0146614=Skp1=PD(28.0=77.8)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)