HsaINT0108865 @ hg19
Intron Retention
Gene
ENSG00000128833 | MYO5C
Description
myosin VC [Source:HGNC Symbol;Acc:7604]
Coordinates
chr15:52567759-52571214:-
Coord C1 exon
chr15:52571070-52571214
Coord A exon
chr15:52567916-52571069
Coord C2 exon
chr15:52567759-52567915
Length
3154 bp
Sequences
Splice sites
5' ss Seq
CAGGTAGCT
5' ss Score
6.52
3' ss Seq
AAAACTTTTATTTGCTTTAGAAA
3' ss Score
6.49
Exon sequences
Seq C1 exon
GAATCATTTTGGTGGCCATGAATCCTTACAAGCAGTTGCCAATATACGGAGATGCCATCATCCACGCCTACAGCGGGCAGAACATGGGCGATATGGACCCACACATATTTGCCGTGGCAGAAGAGGCATACAAGCAGATGGCCAG
Seq A exon
GTAGCTTCCTGCCAAGCTGGACTTCCCCTTGCTCTGCCAATGCTCCCTGCATTTGCCAGACCATCACAGTGGAGGGGAGATATCTAGGTTGGGCTCATTAAAAGAGATAGGCCAGAGGTGGTGCTTTGTTGAGCCGACTACCTGGAATGAATAGCAAACGACTGTTCCATGTACCTGACCTGTCAAGACTGGAGTTTCCTGGGTTTTGTTCCTTCAAGGTAGTCAAGTCAGTCCTACCAGTCTGGGAATAGCAGATGCTTTTCTTGCAGTGTGTTTGGTTGGAGGAGTGTTGATTTATTCTCTGCTATGAGACGTTTAAGCTTTTTTTTTTTTTACCCATTGCAGGAAGTAGGATCTGATGACAGGGTTTTTAGCTGCAGGAGGTTTTAGGTGCAGGAGACATGGAATTTTATCCTAATTTCACTGCTAGGTGTTTGTAGGGCCCTGTGGAGTTCTCGTTTCACTAGTGCACATGTATGAAAAGCCTCCTGTGAATGAGGCACCGTGCACACATTCCCATGTGTCATCTGGGATGGCCTCAGAATAGCCCACGATGCAAATGTCTGGGCAGTAAACAGCTTCAGGGAATAACCAACCCAGGGTAGGCAGCAAGTAAAAGGCAGATCTGGGATTTGTGCTCAGATTTTTAAACTCTAGTTTATTTTTCCCATAACTATCACTTTTGGCTTCAGTGTCTTCATCTGTAAAGTATGGAGAATAGAAACACCACCCTATCTTTGTAGCTGCCTTTACAGTTTGCAAAAGAACTTTCACATACAGTGGTCTCCCTTGAGTCTTACAGCACTCCTGTGAAGTTGACTGACTTCATTGCCCTCATTTCACAGATGGGAAATCTGAGGCACAGGACCTGGACCTGCTGACTCTTTACCTAAATCTTTACTGCATAACCCCAGCCGCAGCTCCTGAGCTCCCTCCGCTTTATGTCTTCGTCTGTGAGCTGGACTCTCAGAGGGCACCCATTCCTGGTTCTGATGCTTATAATGAGGGAGCAGGTGGTGCTTACATGAGGTAGAACACGTGCTGCTTTCCTGCACAGATGTCTGATGGGCAGTCTGGGGCTAGACCGAGCTTCTTCAGAGTCATCAGAGACCCGGTGCCGTGCAGCTCCCTGTCCCTGGGGTGGGGCCGTCATCCTCAGGGACAAGCCAGTTCTCACCTCTGTCTTCCATATTCTAGGTAACAAGGCATATGAGGGGAAGGGTATGGCCCTCCAGGTTAAGGAGACTCTCTGGAAGCCCCACAAAGCACTTCTAACAGCTCGTCAGGCAGACCTCACTCACATAGGGAGGCTGGGATGTGCAGTCTTTCAAATGCACAGAGGGGCACTGCCTGGCCACTGGGGCCTAGTCCCTAAGAAGGAAGAGGAGAATGCAAATGCATACTGGGTAGAGAATTAGCAGCTTCCGCTGCACCAAGATTCCTTCTAACCCTAAAACCCCTGTGGTTCTGAGATTTTTCCCTGGCTCCCTGTAGGTCTCCCAGGTATCGTGGTGATTAGGGACTGGGTATGGGTGGGATGAGCTCTTTGGCACTGTAGGGCTGTGCTCACTTCAGCCCTAAAGAGCCAGTTTCTCCTTGGAGGTCTGTCTGTGTAACTGCCATAACAGAACGGAGCCCAAAGCAGGCTCGTGTTGGCCTTGTTTGATGCTAGACAGGTAGTGTCCCTCAGGGCTGTAGAACAGGGCTGGGATTACTAAAGCCCTGTTCTATGCCCTGAGGGACACTGAGCATGTCATTTCACTTCTCAGAGTCTTCATCTTCTCTCTTTGAAATGAAAATATTGGACCGGGGCTCTGTATCCAAAGTCTCCTCTAGCATTTACATGGGAGGCTGTGGCTCTGTGCTCTGGGTCAAGTCACTCCACCCCTGAGTCACCATTTTACTCTTCTGTAAAAGAGATATCTATGTCGTAGGATTTTTGTGAAGCTTAAATGAGAATCTGTATTCACCCAGCACCTGGCATGTGAGCGGTGCCACATCCACAGAGCCATGTTAGAAGCTTCCACCATCACAGTCTTATGACATGAAAAGTTTAATGCATTTTTAAAAAATCTCTAAATTATATAACAGAGCATGTTGGCTTAGAGAGCGCATATGTTCCCAAGCATCTTTTGAATAATTGCTCTCAAAATAATGTCCTTGAAATGTTTTTATATTTAAGTGGGATGTGCAGAAAGGAGTTGACATAAGGCCTGAGGCTGCTATCTTTAGAGGCCTGCTTGCAAGGTGGCCCATGGCTAGCCTCTGATTTCATGACGGTTCCTGACATTTCTTGGTTGAAAAAGTGGCTCATTTTACCTAAACTCAAGCTGTTTGTGTAAATAATGTGCTTTATGCTGAATACGTGCTTTCCTTCTGGGAGTCTGGAATATTGGCATATGCTAGGCAGAAGGTGGGCACTGCATCTCTAATGAGCTTCCCTGGCAGCCAGCATTTCACATGTGCTGTCAAATTCCTTGCTGGAAGAATTGAATGTGTCCTGTGTGACCCGACTGGGAGAGGACCCCTGGAAGTTTGCACCCGTGTTCCACTGGACCTTGCCCCGTGTGCCTTTTCCCCGTGCTGCTTTTGCTGTGTATCCTCTTGCTGCAATCAGTCTTAGCTGTGAGGATGACTATATGCTGAGTCCTGAGAGTCCTCTTACTGGGTCATTGAACCTGAGGTTGGTCTTGGGGCCCCTCAACATGGTACTCAATAAATACATGTTGACAGGCAGCATGATGACCTACACAGGGTCCATCTAGAAAGAGGGTGCTCAGGAGAGGGTGGGGAAGGCAGAGGAGAGATGAAATGAGAGGTGAAATTCAAGAACAGAGTTTAAAAGCAAAAATCCTGCCCAGAGAGTGGGAAGGATGGGAAGGAGCAGTTTTTTGGTTGAGTGGAAAGGTTGAGTAGGGAAGCAGTAAGGAGTAAGGATTTGAATAAGGTTGGATGAAAGATGTGAACTTTTAAAATTGTGTGTTCTGCACGATCACATAGAAAAAAAAATCTAGAAGGAAATTGATTGAGATTTAAAAATAGTAGAGTGACAAAACAGTTTCCCTCTTTTGTCTTGTCCACATTTGTCTTAATTAGCACATGTTGCCTCTTTAATGGGAAGAAACTAATATTTGAAAACTTTTATTTGCTTTAG
Seq C2 exon
AAACAACAGAAACCAGTCCATAATTGTAAGTGGGGAGTCAGGTGCTGGAAAGACAGTGTCGGCTCGCTATGCCATGAGGTACTTTGCCACCGTCAGCAAATCGGGCAGCAACGCTCACGTGGAAGACAAGGTCCTGGCATCCAATCCCATCACCGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000128833-MYO5C:NM_018728:4
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.071
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=PU(39.6=97.7)
A:
NA
C2:
PF0006316=Myosin_head=FE(18.2=100)
Main Inclusion Isoform:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)