HsaINT0108914 @ hg19
Intron Retention
Gene
ENSG00000137474 | MYO7A
Description
myosin VIIA [Source:HGNC Symbol;Acc:7606]
Coordinates
chr11:76913345-76914262:+
Coord C1 exon
chr11:76913345-76913469
Coord A exon
chr11:76913470-76914104
Coord C2 exon
chr11:76914105-76914262
Length
635 bp
Sequences
Splice sites
5' ss Seq
CAGGTGATG
5' ss Score
5.99
3' ss Seq
CGGTCCCTGTGCTGCGGCAGGCC
3' ss Score
5.14
Exon sequences
Seq C1 exon
GCCCTGGTCACCATGACTCCCGATCAGAGGCAGGACGTTGTCCGGCTCTTGCAGCTGCGAACGGCGGAGCCCGAGGTGCGTGCCAAGCCCTACACGCTGGAGGAGTTTTCCTATGACTACTTCAG
Seq A exon
GTGATGCCTCCTGGGGAAGGATGGGAGCCACAGGGCTAGGAGCTGCAGGCTTCCGCTACTGTCTGGTCGTGTGCTGGGGCTGCTTTGTGAAGCCCCCACCTGTGAGCAGGGCCTGGGTCAGAGGGAGCTGGAGGGCTGTTTCTGTCTGCCAGGATGACCCGTCCTATGTGTCTCATCTTATCTTCCTTCCTTCAAGAGATGTCACTGCACCCACCCCAGGCTGGGCATTCGAGACTGAGTCCTGGTGGGGATGCGGGCTGGAAGCAGGCAGCTGGGATTCGGCGTGCCCAGCACTGTGATGAGGATGCTTCTGGGGCGGGGGGTGGGGGGCAGTGAGAAGCTTCCTGATGGAGGCGTTGTGCACTGAGCTCTACAGGGGGCGCAGGGTGGTGGGGGAGGCTGGGGCACAGCCCGTGGTGTTCTCGCCGCTGGGGTTTCACAGCTGAGAAAGAAAGGCCCAGTGACTGCCAGTGACTCGCCTCGGGTCACATGCAGGGCAGGGAAGAGCAGGGCCTGGTGCCCACTCTCAGCCTCTGGACACAGGGATGGGTGGGGGTGGGGGTCTCACAACCTGGGGGTTTCTCCCCGGGGCTGCCAGCGATGGGGCGTTGCTGACGGTCCCTGTGCTGCGGCAG
Seq C2 exon
GCCCCCACCCAAGCACACGCTGAGCCGTGTCATGGTGTCCAAGGCCCGAGGCAAGGACCGGCTGTGGAGCCACACGCGGGAACCGCTCAAGCAGGCGCTGCTCAAGAAGCTCCTGGGCAGTGAGGAGCTCTCGCAGGAGGCCTGCCTGGCCTTCATTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000137474-MYO7A:NM_000260:37
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.143 A=NA C2=0.056
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGTCACCATGACTCCCGATCA
R:
CAATGAAGGCCAGGCAGG
Band lengths:
278-913
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)