HsaINT0108920 @ hg38
Intron Retention
Gene
ENSG00000137474 | MYO7A
Description
myosin VIIA [Source:HGNC Symbol;Acc:HGNC:7606]
Coordinates
chr11:77208430-77208803:+
Coord C1 exon
chr11:77208430-77208517
Coord A exon
chr11:77208518-77208696
Coord C2 exon
chr11:77208697-77208803
Length
179 bp
Sequences
Splice sites
5' ss Seq
ACGGTAATG
5' ss Score
6.53
3' ss Seq
CCGACTGCCCTGTGCTGCAGGAA
3' ss Score
8.21
Exon sequences
Seq C1 exon
GTCCTCAGCGTTCCTGAGAATGACTTCTTCTTTGACTTTGTTCGACACTTGACAGACTGGATAAAGAAAGCTCGGCCCATCAAGGACG
Seq A exon
GTAATGAGGCCGGGTCCTGGGATCATCTGAGGCCCAGAGCAGGGAAGTGTGGGCTCGGGGCTGTGCCGTGAGGCCCACCTAGGCGGGCCTGAGTGAGGGCCTCCTCTGGGTCTGGGCTCGGGACGTGAGCACTCCTCTGTGCAGGGACCCTCTGGGTGACCGACTGCCCTGTGCTGCAG
Seq C2 exon
GAATTGTGCCCTCACTCACCTACCAGGTGTTCTTCATGAAGAAGCTGTGGACCACCACGGTGCCAGGGAAGGATCCCATGGCCGATTCCATCTTCCACTATTACCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000137474:ENST00000409709:43
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF093795=FERM_N=FE(30.9=100)
A:
NA
C2:
PF093795=FERM_N=PD(18.1=47.2),PF0037313=FERM_M=PU(10.8=33.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCAGCGTTCCTGAGAATGACT
R:
AATAGTGGAAGATGGAATCGGCC
Band lengths:
186-365
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development