HsaINT0108947 @ hg38
Intron Retention
Gene
ENSG00000137474 | MYO7A
Description
myosin VIIA [Source:HGNC Symbol;Acc:HGNC:7606]
Coordinates
chr11:77157279-77158430:+
Coord C1 exon
chr11:77157279-77157392
Coord A exon
chr11:77157393-77158276
Coord C2 exon
chr11:77158277-77158430
Length
884 bp
Sequences
Splice sites
5' ss Seq
ATGGTGAGG
5' ss Score
7.61
3' ss Seq
TCTCCCACCCTGCCCACCAGGGT
3' ss Score
6.97
Exon sequences
Seq C1 exon
GCCCTGGATGAAAGGAACTACCACGTGTTCTACTGCATGCTGGAGGGTATGAGTGAGGATCAGAAGAAGAAGCTGGGCTTGGGCCAGGCCTCTGACTACAACTACTTGGCCATG
Seq A exon
GTGAGGCCCAGGTGGGCCCCTGGGTAGGGGGGCACCCACCCTAGGATTGTAGGGAGCTGGCTACTGCAGACTCAGCCTTGAGGTCTCACTGGTCACAGGGCTCAGGTGCCAGCTTCTTGCTGGCTTGTCTGGACACCAAGGAGAAGTGGGCTCCTGGCCATTGCTGCCACCAAGCAAAGGGTGGGGGACCTTGGGGCACGCACACGGCAGGCTGGCTTGGGAAGCACCACTCCTTTAGCCATGGGGAGAGCCCATGTCTGGTTGCCTGGGCTGGGCTGGGGTGGGCCAGGCCACATGGACGTAAGTGTGGGCTATGGCACCTGAAGCGTATATGTGTGTGTGCATGTGTGTGTTGTAGGTGTGACAGGTGTCCCTGGACACTTTCTGTAGCTGGCTGGCACACACGTGCACACACACACACTCTTGTAGACACACAGAGAATGGGGTGTGCCCACTGTTGAAACCCTGCTCGTATGCAGTTACCTCTCCTCTGTCTACACCAGGCAGTACCTGCCTAGGGGGTCGAGTCCCTGATAGTGGGTATCCCCGGGGGGCTGCAGGAGCCTAGTAGGGCCTAAGTGCTGTGACTGCCAGGTGGGCAACAGGGGCTGGCCTGGCATCAGTGACCTGCCTGCTCTTCATGGGAAGAAGGGGCACCAGCACCCCCAGATGTGGAGAATGAGTTCCTGGGAAGCCCAGGCTTTCTAGACCCTCCAGACTTTCTGGAGGAGTTGTGGTGCTCACCGGGTGAGGTCAGCGCCTGGGGCCCCGGGCTGGCCTGGCCTGTCAGGCAGAAAGGGCCTTTTGGGCAGGCAGCCAGGCACTGCCCCTCTGGGGGTACACTGACGTCCTCTTGCACCCCACTCTCCCACCCTGCCCACCAG
Seq C2 exon
GGTAACTGCATAACCTGTGAGGGCCGGGTGGACAGCCAGGAGTACGCCAACATCCGCTCCGCCATGAAGGTGCTCATGTTCACTGACACCGAGAACTGGGAGATCTCGAAGCTCCTGGCTGCCATCCTGCACCTGGGCAACCTGCAGTATGAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000137474:ENST00000409709:8
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=FE(5.6=100)
A:
NA
C2:
PF0006316=Myosin_head=FE(7.7=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCCCTGGATGAAAGGAACTACC
R:
CTCATACTGCAGGTTGCCCAG
Band lengths:
267-1151
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development