HsaINT0108970 @ hg19
Intron Retention
Gene
ENSG00000169994 | MYO7B
Description
myosin VIIB [Source:HGNC Symbol;Acc:7607]
Coordinates
chr2:128381668-128383110:+
Coord C1 exon
chr2:128381668-128381895
Coord A exon
chr2:128381896-128382942
Coord C2 exon
chr2:128382943-128383110
Length
1047 bp
Sequences
Splice sites
5' ss Seq
AAGGTGAGG
5' ss Score
9.16
3' ss Seq
GGGTGCCCTGGGCTGTGCAGGAG
3' ss Score
3.88
Exon sequences
Seq C1 exon
TTCTGGTCCCTGGGCAGCGGGCGCGACCACATGATGGATGCCATCGCCCGGTGTGAGCAGATGGCCCAGGAGAGGGGCGAGAGCCAGCGCCAGTCACCCTGGCGCATCTACTTCCGGAAGGAATTCTTCACCCCCTGGCACGACTCCCGGGAGGACCCTGTCAGCACCGAGCTTATTTACCGCCAAGTCCTCCGAGGAGTCTGGTCTGGCGAGTACAGCTTCGAGAAG
Seq A exon
GTGAGGGGCCTGAGAGCCAGGTCCACCCTAGGCTTTGCCATCAGGAAACATCCCATAGAGGAGGCACCCAACTGGCTTCTGAGGCCAGGTAGAAGGTGGGGGGGCAGGAAAGGGGGTCACAAGGGTGTAGGTCCCTTCCAGGCCCAGCCTCTGTTTCCTCCTCCCTTAGGCCACAGGTATGTCCAAGCCTCCGGGGTCCGTGGTTCTGGCAGCAGGTCCCAGAGGGCCCAGGCCTTGCCTGGCCTCACCTCTCCTGCTCTGTTTATGGGGCAGTGAGATCTGGTGGCCAAGAACATGGCCTTGGAGCCCTAACACCTAAGTCTGAATCCCACCTCCCCATCTTCTTGGCATTGTGACCTTGGAAAGTCCTGTCACCGCAGAGCCCTGGGCCCTCATCTGACTGGGGGGCTCGGGAGGGGCTCTCACCTGGACCGTGCGGAGTGTACCGGGAGCTCTTTTGTAGGGGATTGTGAGAAAGCAGAGTGATCGTACCCCTGAAGTTCTGGGGGCAGCAGGCACAACCCTCCCTGTGCCAAGTCAGGCAGATGCTGTTCCGGGACCCATTGGAGGCGGCCATAGCAGTGCAGGAAGCCCGCCTGGAAGAGGCATGGGCAGGGGGTGGCAGGGGACCAGGCTCCAAGAGGCTTTGGTCTTCCAGAGGGAAGGGGCTCCTTGGGTGCTGCCCAGCTGGGCCCCAGCAGAAACTCCGCAAGGGGGGCTACTGGTCTCCCTTGACAACCAAGGACTGGAACTCAGATGAGGAAACGCCTTGTCACTCAGAGCAACCCTGCTGGGTCCACCCCAGAACTGGAGAGCAGCCGTTGTCCTCAGGCAGAGGGCCTGTGAGGCTCTGGCCAAGGCCTCTGGGATTCCCAGCCTGCATGGTGGCCCAGTCAGGGCATGCAGGGAGGGGGAAGGTCCTGCCCGAGCCACAGGTTAGCTCCCCTGTGATGGGGCAAGAGCCCGGCCACGGGACAGGGGCATCCTGGGGAAGGGGGGAGCTCTCACTTGTCTCACTCGCCCCCGTGGGTGCCCTGGGCTGTGCAG
Seq C2 exon
GAGGAAGAGCTGGTTGAGCTGCTGGCCCGGCACTGCTACGTGCAGCTCGGCGCCTCAGCAGAGAGCAAGGCTGTCCAGGAGCTGCTGCCCAGCTGCATCCCCCACAAGCTGTACAGGACCAAGCCCCCAGACAGGTGGGCGAGCCTCGTCACTGCCGCCTGCGCCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000169994-MYO7B:NM_001080527:29
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.062 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF093795=FERM_N=PD(47.3=56.6)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTCTGGTCCCTGGGCAGC
R:
GGCTTGGTCCTGTACAGCTTG
Band lengths:
353-1400
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)