HsaINT0108985 @ hg19
Intron Retention
Gene
ENSG00000169994 | MYO7B
Description
myosin VIIB [Source:HGNC Symbol;Acc:7607]
Coordinates
chr2:128392695-128393482:+
Coord C1 exon
chr2:128392695-128392801
Coord A exon
chr2:128392802-128393296
Coord C2 exon
chr2:128393297-128393482
Length
495 bp
Sequences
Splice sites
5' ss Seq
CAGGTACCG
5' ss Score
10.05
3' ss Seq
CCAGTGTGTCCATCACCCAGGAG
3' ss Score
4.84
Exon sequences
Seq C1 exon
GGGCCCCCGTGACGCTCCCCTACCAGGTGTACTTCATGCGGAAATTGTGGCTCAACATATCTCCAGGGAAGGATGTGAATGCAGACACCATACTCCATTACCACCAG
Seq A exon
GTACCGGGCAGGCTGCCCTGGTGGGCACTGGGGCCACCCCCATCTTCCCACACCTGTTCTGAGGCTGTAGAAGCCAGCAGGCCAGGGCAGGGCCAGCCTCAGCCCTGGGTACCAGCCCATGTGGTAGGCAGACCAAGCCCCTGAGGGCTCTGGAACCAGGAGCAGAGGGCAGCAATGTTTGGGGACAGTGACTGCACTGGCACCTGCAGCATGACTTGGAGAGGGTGGGACAGAGGGTCCTGTGACCCATGGAGCAGTGGCCGTGGCCTGCAGGGCCAACCACATGGGTGGAGCAGGCCATCACCTCCACGCAGATGTCAGGGGGCCCTGCCCTGACTCAGGGTCATTCCCCTGGCCTGAAACTCTCTACCCTGCTCAGTCCGTCCTGGATGGAGTGGGCTAAGCCCCAGTTCCCCACCATCTGAGCGGGAAAGAGGTTGGGGGCGGGTGGGCCGCAGCTGGAGACCCAGCATGCCCAGTGTGTCCATCACCCAG
Seq C2 exon
GAGCTGCCCAAGTACCTGCGCGGATTCCACAAGTGTTCGCGGGAGGATGCCATCCACCTGGCGGGCCTCATCTACAAGGCCCAGTTCAACAACGACCGGTCCCAGCTGGCTAGTGTCCCCAAGATCCTGAGGGAACTGGTGCCTGAGAACCTCACACGCCTGATGTCCTCGGAGGAGTGGAAAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000169994-MYO7B:NM_001080527:42
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF093795=FERM_N=PD(18.1=47.2),PF0037313=FERM_M=PU(13.9=44.4)
A:
NA
C2:
PF0037313=FERM_M=FE(53.0=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCCGTGACGCTCCCCTAC
R:
TTTTCCACTCCTCCGAGGACA
Band lengths:
286-781
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)