HsaINT0112603 @ hg19
Intron Retention
Gene
ENSG00000119408 | NEK6
Description
NIMA (never in mitosis gene a)-related kinase 6 [Source:HGNC Symbol;Acc:7749]
Coordinates
chr9:127109988-127114719:+
Coord C1 exon
chr9:127109988-127110101
Coord A exon
chr9:127110102-127113115
Coord C2 exon
chr9:127113116-127114719
Length
3014 bp
Sequences
Splice sites
5' ss Seq
AAGGTGAGT
5' ss Score
10.47
3' ss Seq
CACCATTCTCTCCCCTGCAGTTA
3' ss Score
9.71
Exon sequences
Seq C1 exon
ATGGCAGCCCTCCAGAGCCCCTTCTATGGAGATAAGATGAATCTCTTCTCCCTGTGCCAGAAGATCGAGCAGTGTGACTACCCCCCACTCCCCGGGGAGCACTACTCCGAGAAG
Seq A exon
GTGAGTTTGCAGGAGCCGGAGGCCTCGCCAGCCCCAGGAGGCCACCGAGGCTTATGAGGGCCGCTCCAAAACACCACAGCTGTGGGGCTGAGGTTAGGCTCACTTTACACGGTGCAGAAAGGGAGCTTTCTGGAAAAGTGACTTGGAGAGGGGAAAGTAGGTGATTGCACTGAAGAAGGGGTTTCACCACGCAGCTCCAGTGTGGGACCCCCAGGTAGGAACCAGTGGCACGTGGCCCTTGGCACATCTCCACCTGTTCAGCTCCCAACTTGGTGCTCCAGTGGGAGGCCCTCTGCTGCAGGTCCCCAGGACAGGGTCTGTGCCGTGCCAGACATGGGAACTGATACAGGGGCAGGATGTGGCAGGCCTGGCGTCCCCATACCACCAGTGGTGGCCACTCTGCTCCCATGACAGGAAACTACGGCAGGAGGACCGGTCAGTTTCCTCCTTATATAACAGACTTAACACCCTGGGCTTCTACTGTCAACATTTTACACTGGCTGCGGGAGCCGTGGACACAGCTCCCATGGGTCTGGCATGGGGCTGTACCAGTTACTAGGAATGTGTGAATATCTTATTCCTCGGCTCCGTCACCTTGAAGATGGGACTAATAATCTCCTTGGTGGATAATGGTGAGGAAGAAAGGACAGGTTTCCTGGCACAGCAGGGTCAAAAGTGTAGATACATGTTCACACACTCTCTGCACTGTTCCTAGGTGAGTCACCTAACCTCCCTGAGTCTCAGTTTCCTCACCTATACAATGGGGATAATATTAAATCTTCCACACAGGATCAGCATAAGGATTAAGGTAAGGCACCAGGCTAACACTGCCACCACCATCCAAAGTGGCCAATGGATGGGGCCTGGCTCAGTCAGTGTTCACTAAATATCATGTGACCCTTATTTCTGTTCAAGGTCAACGCTAGTGGGTGAGTCTGGGGCCTCCGTGGGCCCACCCCATAGGACCACAGGCCGTCACCTCACGATAATAACAGCTCATGTTCAGACTTCCTGAGTTGAATCTTCCCCTCACCCATTTACCAATAAGGAACAGACAGACACAGGCAAGTTAAAAAGACCGGTGAGGCAGGATCTGAACCCACATGCGCAGCCACGGAGCCATCGTGCTTCTTGATGGCATGTCTTTGGTGGCCCATCAATTAGCTGGGGTGAGGCTCTGGAAGGAGTGCCCTTGCCCCGGCCAAACTGCACAGGGCAGGTCCTGGGTGCTGCGCTTGTGTCCAGGCCGGAGGCTCCTCGCAGGGCACCTGTGCTGAGCCTGTGCTTGCTGGCGTTGCAGACTCCAGGGCTAGAGGAGCTCGAGTGTCGGGCGCTGCACAGTGCCCTTCCTCTCCTGGCTCCCAAGTTCTGACCTGCACTTTTGGAGGAAGTATTTCTCCTCCCCAGTGGGAGGAAAAACAAGTTGCATCTCTTTACAAAGTTAATAGTTGCCATTTGCTTTTTTCCTTTCTCATCTTCTGAATTCGGACTTGTGTATGATTCAGAAGCTTGAAGCTGTGCAACTGGAGCTGGTGACAACTCTGTGCTTTGGCTGTCAGTCTAGAAATGGGAGTCGCCCTCTCTACTTCAGTGATGAGGCTGAAATGAACATTGAAGCCCCTGTCCCAAGTCAGCCCTTTCCTGGCCACGAGCCCCCACTCCCCGGAGCACTGGCTCTCGCCGGGCCCCATGCTTAGGAGTGAGAGGTGGTGCTCAGGAGCCCCCAGCACACCCTATTTTAAAGTTATATCGCTGCTTAGAAATGAAAATAAGACACTTTTATTATTTTTCTCTTGAATTCTGAAAACTTCAAACATGCACTTATTGACAACTGTGCGTTTACTTCATAAATTAGTTCGGGTCACAGACACTTCACCTGAATCTGGTTTTCTTGGGTATTTTAACCTGTCAGAGGCCAACCACAGGTACCTTCCCCCGAATATTGTAAGGTTCAGAAAACAGCTGTCTTGTCCACAGGCGACTTCAGACTCCGGGAGTGGCCTAGCAGGCTGCAGGCCCTGTGTCACCTGGGCTTCTCGGTTGTAAGGCATGCACGCAGGTGCGAGGGGATACCCTAAGGCTCTGTGGCCCAGGGAGAAAATGCCCCATCAGCTGAGAGGAGCCCTAGTCTACAGGAAGCCCAGGCCCCATCCCTCAGCCTAACGGGCCTGCGCAGCAGTAGCCCCCGGGCCTCCAGAACGTCCCGTGGGCCCTTCCCAGTCCCTGAGTGAGTGTGGCCACTGAGACCACCAGAGCCCCCTCTGGTTCAGGACCACCCAGCTTCCTGCTGCTGCTGCTGCTTCGGCTGCTGTGGCCTGCGGGGCTGACCACCCCTCCAGCAGCAGGTATTTAAATGGAAACCAATGGCTGTGAGCCCGTGATGCAGGGTAAGATGTAGGCATTTTAAGGTCATTATTTTAATTACCATTAAAATAATTGGCACTCCGGCTATCAGAAGAATGGAGGCGATCAGAGGCGCAAGGCGCCCCTCCCCCACCTCGGGGCGGGAGCAGCCTTCAGTGTCTGTATAATTAAAAGCTCCGTCTTTCATGAGCACAATAAAGGGGCCGGGGGTGGGCAGACTGCAGCCCTGCTGCATGTTAATGCGTTTATTATGATCAATAAGCCCTTGCCTTGAGTTTTGTCCTCTGGTTTGGGCATCTGCGTGACTGACAGCAGACACACACACACACACACACACACACACACAATTTGCCCAATGGTGTGGACAGCTACAAGTTCAAAATAATTTGGAGGTTAACCATTCTTAGGGTCTCAAAGCACAGCCTTTGGGACTAGACAGGCCTGGGAGGGGTACTGGCTAGCCCTTGGGAGCCATGCGGCTGCGCACCCCTTACTTGCCCCAGCTAAACACCGTTCTTCAGCTCTAACGGGGACAACGGGACCATCTAGTTGCTCTGAGGATGAAGTGCCTTCATGCAGACAGACTGTGGAGTGCGGAGCCTCAGTAAGACTGCTTTCTTGAGAATAACACACCATTCTCTCCCCTGCAG
Seq C2 exon
TTACGAGAACTGGTCAGCATGTGCATCTGCCCTGACCCCCACCAGAGACCTGACATCGGATACGTGCACCAGGTGGCCAAGCAGATGCACATCTGGATGTCCAGCACCTGAGCGTGGATGCACCGTGCCTTATCAAAGCCAGCACCACTTTGCCTTACTTGAGTCGTCTTCTCTTCGAGTGGCCACCTGGTAGCCTAGAACAGCTAAGACCACAGGGTTCAGCAGGTTCCCCAAAAGGCTGCCCAGCCTTACAGCAGATGCTGAAGGCAGAGCAGCTGAGGGAGGGGCGCTGGCCACATGTCACTGATGGTCAGATTCCAAAGTCCTTTCTTTATACTGTTGTGGACAATCTCAGCTGGGTCAATAAGGGCAGGTGGTTCAGCGAGCCACGGCAGCCCCCTGTATCTGGATTGTAATGTGAATCTTTAGGGTAATTCCTCCAGTGACCTGTCAAGGCTTATGCTAACAGGAGACTTGCAGGAGACCGTGTGATTTGTGTAGTGAGCCTTTGAAAATGGTTAGTACCGGGTTCAGTTTAGTTCTTAGTATCTTTTCAATCAAGCTGTGTGCTTAATTTACTCTGTTGTAAAGGGATAAAGTGGAAATCATTTTTTTCCGTGGAGTGGTGATTCTGCTAACATTTTTATCTACGTTTTATAACTTGGTGAGTGACGATGAGAGCCCTGCACCTGGCCAGAGTGTCACAGGCAAAAGGCATCGGGAAGCAGGAGCATCTTCTTGGCAGCCAGGCTGGGCCATCTTCTCCTGGACACCTGCTGTGTACCAGGAACTTCGTCACCTCCTTGAATGCTGGCGGTTCATTTCATGATCAGTGTTAAGCATTTTCCTCCATGGGAAGGAAGCATGGGATATAGAAAAGCGAAGGGCTGTCCTTTACAAATTCTGGTTCTGCAACTTCCTAGCGTGACTTTGGGCTTGGGCAAGTTTCTTAGCCGTTCTGAGCCTTCATTTCCTCATCTGTACAATGAGATTAATAGTACCTATCATCTACCTTCAGGATTGCTGACAGACAGAATTTGAAATAAAATATGCAAGTTAGCTAATACAAAAAGTAGATGATCCAAAAATGGTAGCCACTCACCCTTCACAAACTGAAGTCCATGGACCACGGAAGTCGAGAATTAATGTACACCTGTATCATGTGTAGGAAACCAGAAATGTGTTCCTTATTTCTTGTTCCCAAACAGGATTAACTGTGAAGACTAATTTATAAATGTGAACCTAAGAAAACTCCACCTCTGAAGGAAATCATTTGAATTTTGTTTTTGTACGTAAAGTTAACCTTCCAATTGTCTGAGCTGTCGTCACTGACTTCATGACAGTCTGGCCCTCCAGACAAGAGCAGCGCTGGCATCGGGCAGGTGATTCCTGACACCTGCTGCCTGCAGGCATTCACTGACCAGGCCTTTCCTGGAGGAAACACCCAGGGCCGGGCGGCTGCTGTTTCCACACGTGGACTCGGATCTGCTGTGACACCGTCAGCCCGACAGTCTCTCCATATGCAGCCTTTCCTCTGTACTTTTCTCCATGGTTGAAATAAAACAGGGTGACTGGGAGTTACTTAGAATTCATGAAGATTTTAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000119408-NEK6:NM_001166171:10
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=PD(16.3=93.3)
A:
NA
C2:
PF0006920=Pkinase=PD(10.7=75.7)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)