HsaINT0124973 @ hg19
Intron Retention
Gene
ENSG00000133056 | PIK3C2B
Description
phosphoinositide-3-kinase, class 2, beta polypeptide [Source:HGNC Symbol;Acc:8972]
Coordinates
chr1:204429678-204433260:-
Coord C1 exon
chr1:204433140-204433260
Coord A exon
chr1:204429790-204433139
Coord C2 exon
chr1:204429678-204429789
Length
3350 bp
Sequences
Splice sites
5' ss Seq
GAAGTGAGT
5' ss Score
7.97
3' ss Seq
TTGTCCCTCTACCCTACCAGCAA
3' ss Score
6.23
Exon sequences
Seq C1 exon
GTTCCTCCACTGTAGACTTGCTTATCTACCAGACCCTGTGCTACACCCATGATGACCTGAGGAATGTGGACGTGGGTGACTTTGTGCTAAAGCCCTGCGGGCTGGAGGAGTTCCTGCAGAA
Seq A exon
GTGAGTGAATGGGTGGGAGGTAGCCCCTGCCTTCCTGGTAGTAAGATTGTGAGGGGGCTTCATGGGATTGGTGCTGGGACCGGCCTGGCAGCTCCGCCCCAATCCCACAGTCAAGACTCCTGCTTTCTGGGCACACTCTCGGCCACGTAGCACTTTCCCCAGGAGCTCTGTCTTCCAGCAGGGTTGGCTGACGTCCTGAGCCAAGTCTGCTGTGGAAAGAGCTTGGAGCTGGGATTAGGCAAAGACTAGGTCATATCTGCTTGCAGATTCTGCTTATGGAGAGATGTGTGTATTTGTGGGGAGGGGTGGGCTTGGGGAGACTATATGGGTAGTGCTGTATCTCCTGCTCTAGATTATGTGTGGTGTTTTTATGGCTGGGGCAAAATGAGGACTGGGCAGAAGTTCCCTTGTGGAGCCCAGGGGAGAAATTACAATTACTGTCTCTCCCCATTCTCCTGCCAACAAGTCTTTTCCCCAGCTGGCCCGTGCAGCTAGTTATCCTCCTCCCAAAGGCGTGCCTCCAGCTCCTCTCCATCCAGTGCCCTCTCTGGAAAGCAGCCTCCCTGGAAAGTCTGATGTGGACCAGCTGAGGCAACCCCCTTTCCACTACCCTGGGCTCTGGAGGGCTGCAGTGGAAGAGAGGCAGGGGCAAGGTTATCACTTCTCAGATGGTACAGCTGTGTGACAGCAGACAGATAAGATCTGCTTTCCTCTCTTAGGCTTCAGAGCCGCTCCTGCCCCCAGTCTCTGTCCACTTGGAGGAAGCACGTTTTGGGAATAGAGAAAGGAGAGACCTGTGTCTCACTTCTTAGGAGTGCCCTATAAGTGCCACTGCTTGCTTTTTCTCTCTCTTACATTCAGGTCTAGATGCAAGGATGGTTGATCTATGTCTAGAGCATAAGATTTGGCAGTCAGGATGGAAGATTCATTTCTGGACTTCTTTCTTTTTTTGAGACAGAGTCTCACTCTGTCGTGCAGGCTGGAGTGCTGTGGCGCCATCTCACTCAGCTCACTGCAACCTCCGTCTCCCAGGCTCAAGCGATTCTCATGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCATAAGCACCACCACGCCCGGCTAATTTTTGTATTTTTTAATAGAGACTGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCGGGTGATCTGCCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACTGTGCCCAGCTATCTGGGCTTATTTCAAATTTAAGGATATTGTGGGGTCCTTTCTGGCCTCTGCCTCCTCATCTCGAAGCTAAGGGAAAGGAAAGAGGCAGGGTTCTGTATGGTACAACTCCAGGGTACCCTTCAAATGTGCCCCACCTTTAAACTCACTTATGTACACACTTTTCCCCTAGAGGAACAGGAGGGGTCCTAGACTCAGGGTTGCCTGGCAGAGAGAGTGCCAGGTGGCCTGCCACTGTTAGAAGGGAAAAAGGGGACATAGTGGATAAGTTGGAGCTCCTGCTGACGCCATTACACAGGTTTGAATTCGGACTTGCCACTTACTAGTTGTGAAGGCTGATTGATGCTCAGGGCCCTCTGTAAGCTGCAGTGAGGGTGAAATGTGAGAATGACCTGTGAGCAATCAGTAAATACCAGCAGGGAAGGAGCAGCCCACGGAGAGAAGTCCTAGGGCTCTGGGCTGCACAGATACTGCCATTTCCCTTGCAGCACCCCAAATCCTGGAGCCCCTGGGTCCGGAGGTAGTGGGAGCTGTCAAGTTCTACCTTCCTGCTAAGACTCAGGTGAAATATTCTTAGTGAGGTGGGACAGGGTCAGCGGTCCTCAGATCACACCCCTCATACTCTCACTTGAATGCACAGAGAGGAAGGCCTTCCACAGAGAAGATCAAGCAAGTCCCCAGGGGACCTGTGTGCATGACTCCTGGCCTAGGAGCCCCACTCCCACCCAACAGAAAAGCACAATGCTGTCTCCTGGCCCAGCCCCCAGACCCCCAACACATGACAACTGCCTGGGATGGGGGTGGAAAGGACGCTCCGGGGGTTCCAGAAATCTGCTAGTTCCCAAGGAAGCCCTGAGATTTTCTACCCCTGCCTGGCAGGAGGGGCTGATACTGAGGGGGTGAGTGGGTTCAGGATGCAGGCTGCTCTCAGATAAGAACCTTGAGGCAGTCCCGTGGGAGGGTTGGGTTTCCTGCCACCTCCCCCAGCCCCACCACACTCTTCCTTCCTCCCAGGCTCTCCCACCAGGCCCAGCCCCACAGCCCAGCCTCACCACCTCCAGGTTTTGGCTGCACTTCAGTCTTAGATCTGAGAGGGTCTAGATCGGAGATTTGGTCCTCTCAGGATGTGGAGAACCCCTCACTCGAGCCCTCATGGGACCTAGACGACCCTGGGCCCTGCACCTCCGCCAGCTTTTACATATACTGCCCCCCTTATGCTCCTGTCCTCTCCTCTCCATTTCTGGCCTAGATTCCCAGCTCTGCTGAGGAAGGAAGTCCTTTTCCGGCTTCTGTTACCCAGCTGCTGAGGCCAGGCCCAGGCCTGCAGTGCTGGCCTGGAGGTAGTTCTCCCTCTGCCCCTCCTCTTGGGTTTCCTTGCTGTTGAAGGTGTGATTTGGGAGAGAGGAAGAGGTTGGATCGCCGAGGGCTCCTAGGCCTTCTCTCTGAAAGGGGGAGTCTCACACATGGGTGCTTGAGCAGGTGGGACTGGCATGCATTTGGGACTTTTCAAGAAGTCATAGAAATTTGTAAGGTTATTCACAAGCAGGCAGGGCCAACAGATGGAAGGCAGAAAAAGAAGTTGGGTGGGGACACTGATCTGGAGGCTTGGTAGGCTTGCCCCAAGTTTTTTTGGCCTCAGCACCCTAGTTGGTAGCATTGGAAGAGGGGTCTCTCGCTGAGCTCCCACCCTGGAGCCTGAGCACAGGTGGACTCCAACATGTCTCTTCCTGGTTGTCCCCTATACAGAGGCCCAGAAGATAGGGCTTCAGCAACTGCTCCCTGTGATGTGCCTCTGTTTCCCCGCTCTCTCCAACAGTTCCCAGCCCTGGAGTGAACCAGTGATTACCACACGGGTAATAAATATCTAAGAGAGTCAATATTTATACCGGCCAAGGATTAAGTATATTAGGTGGCTTTTGTTTAGATAGACCTCTGTTCCTTCTCCTAAGCTCTACCGTGTCATTTTCTAGGAGCCAAAGTAGGGTACAACACGGGTACTACCCCCTTACCTAAACCTTCTTTCTGTATGTCTCTCCCCAAGGCTAAGGTATGTATCTCCCTTGCCACTGAGTCCCCAGGATGCTAATGGTCTTGTCCCTCTACCCTACCAG
Seq C2 exon
CAAGCATGCCTTGGGCAGTCATGAGTACATCCAATACTGCCGCAAGTTTGACATTGACATTCGGCTACAGCTGATGGAGCAGAAGGTTGTGCGCAGTGACCTGGCCCGGACG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000133056-PIK3C2B:NM_002646:6
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.044
Domain overlap (PFAM):
C1:
PF0079413=PI3K_rbd=FE(38.8=100)
A:
NA
C2:
PF0079413=PI3K_rbd=PD(28.2=76.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)