HsaINT0124991 @ hg19
Intron Retention
Gene
ENSG00000139144 | PIK3C2G
Description
phosphoinositide-3-kinase, class 2, gamma polypeptide [Source:HGNC Symbol;Acc:8973]
Coordinates
chr12:18656215-18658395:+
Coord C1 exon
chr12:18656215-18656351
Coord A exon
chr12:18656352-18658225
Coord C2 exon
chr12:18658226-18658395
Length
1874 bp
Sequences
Splice sites
5' ss Seq
AAGGTTTGT
5' ss Score
7.81
3' ss Seq
ATTGTTTTTCAATGAATTAGGCC
3' ss Score
4.8
Exon sequences
Seq C1 exon
GATTGGTGCAGATGGTACCTGATGCTGTGACCCTAGCAAAGATTCATCGCCATTCTGGACTGATAGGACCATTGAAAGAAAATACAATTAAAAAGTGGTTCAGTCAGCACAACCACTTAAAGGCAGATTATGAAAAG
Seq A exon
GTTTGTCCTGTTGCAGATCATTTTAAATAATGTACTTAAATAAGAATATGCTCTGGTTCATTAGATATTCTGATTTGTAGAAAAGTAAATTAAGTGCACTTTGAGTTCTAATTCAATCAGCCCAGTAATTAATTAATCAGCCCAGTTTAAATGATATATTAACTACATAAAAGTTTCTGCATTTTATTTAGTTTCTGGGTGAAATTCCTGGTTATCAATAAAGATTTTTTTTTGCTCAGCTGCCATCCTGACATCAATCTTACACCAGAAACAATAACCCTTGAAATTACCTCATTTAAGTAATCTACAACTTCTATAAATATCCCTTCTTTTCTTTGCAATACATTTCTTCTGCCATTCCCCACTTTTTCGTCTCCCATTTTCTTAATGGTTTGCAAAATGCAAAACAGAGTTTATGTATGTCATAATTTTACCAAATGTACTGTTTTATTTGACTGCAAACACTTTTTCTCAATGTTTACTTCATTCTGGTATCTGGCTTGCAGTGTACAGTTGTGCAGGTTCTGCCCTGTATTAGGGATCTTGGCTAAGGAGATGAGTGTGGCTAGAACCAGTCCTTGGTCCACTTGCCAAGCTATGATCTAGTACAGCTGGGTCCACCCAGAGGAAGGAGCACCTAAATGCTAATTCATGCAAAAAATGCACCATTAGATTTGCTTGGTACTATCCTGTGCACTGAAATCCCCTTATTTTGAGAAATTCCTCAAACCTGGGTAAACTGGGATGATTGGTCACCCTACCTATGATAAAAAGGCCATGATAAAATAGACCCCAGAGTTCATCTATTCCACACTTCCATAACATTGTGTTGGAGCAAAATACAAGCTTTACAGGCCAAATAATAAATAATTAGATAAAATTACCTTGAAGTCTACTTTTTAGCTGTTCCCAAAATTATAACTTCAGTTTTGCATTAATCCTTGTGGTTACGTTATTTCCAAATACATCGCTCTTCACAACCACCATTTGAAGGATATGTTTTATTATTTTCACTTTCTAAGTGAAGAACATTTGGATTGACAAATTAAGTGACTTGCTTAGGCATGTAGGAAACCTAGAACTAAGGCACCCTAGCATGTAGCCTGGTGACCTAGCCTTCACTACATCAAGGCAGCCCCTCCATGCTAGGAGACCCATAACCTTATCCCAACCAGTCATTCCTGGTTACACCACCAAGTTGATGAAATGATGTATACCCAGGAGATCATTTTGGACGCAAAGTGTATTTTTGGAAAGAAACATCTGCTCATTAGAGAAACATAAACACAAATTGACTTAATGATAATCTGCTTCCACCCACACAGGCATTCACTGATATATATGTACTATACCAAACAGCTTCAGACATCAACTACATTGATGACCTATTTGTAAAAATACACATAAAATGTTACAGATTTCTCAGTATAGCTTTCTCTGTATTCCAAAATTTCAAATATTCAACCATTGATATTTTAAAATTCCTCTGGGAATAGGCAATATTGGGGCGTATTGTTCCTCCTTTTACTTTGAAAAAAAATCATTCAATATTGTATATTTGAGGTATCAAAAAATGACACTAGGAAACCTCTCTAGTGAACCAATGAAAATTAGCTCCATCTGAATGAAAGAAATATTTTCCGCAGTTTCAGTGAAAACATTCATCTATTAGGCTAAAGAACAGTTGTTTCATATTCTTCTGTAGCAGATCAAGAATCAGCTGCTTAACTGTACCCTCCTGTCCACTGAGATGTAGAAATTTTTCCTGATTATGTAATTTTGCTTATCATTTACTTTTTATGATTACCTCTGATGCTAATGCATTTGCTCATTTTTTGTTGTTATTTTTGCATGATTGTTTTTCAATGAATTAG
Seq C2 exon
GCCTTGAGGAACTTTTTCTACTCCTGTGCTGGCTGGTGTGTGGTAACATTCATCCTGGGAGTATGTGACCGTCACAATGATAATATCATGCTGACAAAGTCGGGCCACATGTTTCATATTGACTTTGGAAAATTCTTAGGTCATGCACAAACATTTGGAGGGATAAAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000139144-PIK3C2G:NM_004570:22
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0045422=PI3_PI4_kinase=FE(20.8=100)
A:
NA
C2:
PF0045422=PI3_PI4_kinase=FE(25.9=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGCAGATGGTACCTGATGCT
R:
CTTTTTATCCCTCCAAATGTTTGTGC
Band lengths:
302-2176
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)