HsaINT0135677 @ hg19
Intron Retention
Gene
ENSG00000126838 | PZP
Description
pregnancy-zone protein [Source:HGNC Symbol;Acc:9750]
Coordinates
chr12:9311016-9312621:-
Coord C1 exon
chr12:9312534-9312621
Coord A exon
chr12:9311173-9312533
Coord C2 exon
chr12:9311016-9311172
Length
1361 bp
Sequences
Splice sites
5' ss Seq
TTGGTAAGA
5' ss Score
8.85
3' ss Seq
TGCATTTTTCCTCCCCCTAGGCT
3' ss Score
11.74
Exon sequences
Seq C1 exon
GTTACCAGAGACAGCTGAACTACAAACACCAAGATGGCTCCTACAGCACCTTTGGGGAACGATATGGCAGGAACCAGGGCAACACTTG
Seq A exon
GTAAGAAAGAAAATCTATTCTGAGTTTCAACTATGAGTTCAGAACGTGCACATAGATTACCTGTCTTAGTCCATTTTCTGTTGCTTATAACAGAATACCTGAAACTAGGTAATTTATAAAGAAAAGAAATTTATTTCTTATAGCTATGAAGGCTGATAAGTCAAAAGTCTAGGGGCCGCATCTAGTTGAGAGTCTTCTTGCTGGTGTGGACTCTGAGGAGTCCCACGGTGATGCAGGGCATCATATGACTAGAGGATTGAATGGGCTCACTTGGGTCTCTCCTTCTCTTCTTTTCTTTTCTTTGTTTTACTTTGTAGAGACTGGGCTAGCATCTCCTCCTCTTCTTATGAAGCCACCAGTCCAACTGTCATGATAGCCCTTTAATCTAGGAATAGATTCATCCATTCATGAGAGCAGAACCCTCATGAGCCAATCACCTCTTAAAGGCTCCACCTCTCAATACTACCACATTGGGGATTAAGTTTTAACATGAGTTTTGGTGGAGAAACAATTTCTAAACCATAATGTTACCTTATTTAATTCTTATAGCTACCCTGGGAAGTGAGAGTTATTAGCTTCATTTTACAGAGGAGAAAACATATTCAGTGTGGATAAATAAATGTGTCAGGAGCAAACATCTAATAAGTGGCAAAATTGAGAACACTTTTAGGTTGATTTTTTTAATCCAATATACCCAGACCCTCTTCCTTCTCATGTTGCTAAGGGAACATTATAGGTTTGTAACTTGCCCCCTTAAATTGTTGCTCAGCCCTAAGAGGTGTTAGAAAAATGCTAGAATAAAACCACAACCATTACTGGCAGAGCATACCTTACTACCTTCTACTAGATGATATCCTTTCTCTCTCTCTCTTTGTAGTTTTACCACACAGGCAAACACAGGGGAAAAAAGTGGAAGGGCAGGATGATGGAGGGAAATATTTACTGAAGCAGAACATTAGAAGTTAGCTGATTAGAGTTAAAACTACAGAAAGTAAGCTAAGAAATCTAGGAAAGGAAATAAATTCATAGAGCCCACAGTGTAAAAGCAAATGACTTAGTTAACCAACCAAGAAAACTGGAAGGAACCTGAACCTCTGAAGTGGCATAGAAATGCTTTAGGAAGCAAGGACAAGCTGGTAATGAATTGAACAACATGTGGCAGCAAAAAAAAAAAAAAAAAGAAAAGAAAAGAAAAAAGAAAAAGAGATGTCTAAGCTAAAAAGAAAAAGTCTCCAAACTCTCAGTAACAGCTGATTGACTTTCTTGGGTGCACACTGTGATGGGGGAGCCTGTGTGTACAAAACAGAGCAGTAAAGTGCTCAATGAAAAGAGCCTCAGCACTGCATTTTTCCTCCCCCTAG
Seq C2 exon
GCTCACAGCTTTTGTACTGAAGACTTTCGCCCAGGCTCGATCCTACATCTTCATTGATGAAGCACACATTACCCAATCTCTCACGTGGCTCTCCCAGATGCAGAAGGACAATGGCTGTTTCAGGAGCTCTGGGTCACTGCTCAACAATGCCATAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000126838-PZP:NM_002864:25
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.033 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF076789=A2M_comp=FE(11.3=100)
A:
NA
C2:
PF076789=A2M_comp=FE(20.2=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTTACCAGAGACAGCTGAACT
R:
GCATTGTTGAGCAGTGACCCA
Band lengths:
238-1599
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)