HsaINT0135707 @ hg19
Intron Retention
Gene
ENSG00000172053 | QARS
Description
glutaminyl-tRNA synthetase [Source:HGNC Symbol;Acc:9751]
Coordinates
chr3:49136033-49136422:-
Coord C1 exon
chr3:49136318-49136422
Coord A exon
chr3:49136126-49136317
Coord C2 exon
chr3:49136033-49136125
Length
192 bp
Sequences
Splice sites
5' ss Seq
GAGGTAAAT
5' ss Score
8.39
3' ss Seq
ACCCCACTTCCTATCTCTAGGAG
3' ss Score
10.6
Exon sequences
Seq C1 exon
TCCTTGGACATCCAGGTGCCCAACTTCCCAGCTGATGAGACCAAAGGCTTCCATCAGGTTCCCTTTGCACCCATTGTCTTCATTGAGAGGACTGACTTCAAGGAG
Seq A exon
GTAAATTGTGGGGGTGGAGGGTCCCGTTTGCTGCTGAGTCTGGTACTGGGAACCTTTCATCTCCTCATCTCTGTCAGTCCATCTACTTCCTGCTTCAGATGAACCAATCTTTGCCAGACACGGGGGTAGGGAAGCTTCCCCACTTGTTTGACCCTTGCAGCCTCATGTGTCTACCCCACTTCCTATCTCTAG
Seq C2 exon
GAGCCAGAGCCAGGATTTAAGCGCCTGGCTTGGGGCCAGCCTGTGGGCCTGAGGCATACAGGCTACGTCATTGAGCTGCAGCATGTTGTCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000172053-QARS:NM_005051:19
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.032
Domain overlap (PFAM):
C1:
PF0395013=tRNA-synt_1c_C=FE(18.1=100)
A:
NA
C2:
PF0395013=tRNA-synt_1c_C=FE(16.0=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGACATCCAGGTGCCCAA
R:
CTTGACAACATGCTGCAGCTC
Band lengths:
194-386
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)