HsaINT0135707 @ hg38
Intron Retention
Gene
ENSG00000172053 | QARS
Description
glutaminyl-tRNA synthetase [Source:HGNC Symbol;Acc:HGNC:9751]
Coordinates
chr3:49098600-49098989:-
Coord C1 exon
chr3:49098885-49098989
Coord A exon
chr3:49098693-49098884
Coord C2 exon
chr3:49098600-49098692
Length
192 bp
Sequences
Splice sites
5' ss Seq
GAGGTAAAT
5' ss Score
8.39
3' ss Seq
ACCCCACTTCCTATCTCTAGGAG
3' ss Score
10.6
Exon sequences
Seq C1 exon
TCCTTGGACATCCAGGTGCCCAACTTCCCAGCTGATGAGACCAAAGGCTTCCATCAGGTTCCCTTTGCACCCATTGTCTTCATTGAGAGGACTGACTTCAAGGAG
Seq A exon
GTAAATTGTGGGGGTGGAGGGTCCCGTTTGCTGCTGAGTCTGGTACTGGGAACCTTTCATCTCCTCATCTCTGTCAGTCCATCTACTTCCTGCTTCAGATGAACCAATCTTTGCCAGACACGGGGGTAGGGAAGCTTCCCCACTTGTTTGACCCTTGCAGCCTCATGTGTCTACCCCACTTCCTATCTCTAG
Seq C2 exon
GAGCCAGAGCCAGGATTTAAGCGCCTGGCTTGGGGCCAGCCTGTGGGCCTGAGGCATACAGGCTACGTCATTGAGCTGCAGCATGTTGTCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000172053:ENST00000306125:19
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.030
Domain overlap (PFAM):
C1:
PF0395013=tRNA-synt_1c_C=PU(43.6=97.1)
A:
NA
C2:
PF0395013=tRNA-synt_1c_C=PU(35.4=90.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGACATCCAGGTGCCCAA
R:
CTTGACAACATGCTGCAGCTC
Band lengths:
194-386
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development