HsaINT0137686 @ hg19
Intron Retention
Gene
ENSG00000111344 | RASAL1
Description
RAS protein activator like 1 (GAP1 like) [Source:HGNC Symbol;Acc:9873]
Coordinates
chr12:113544902-113546027:-
Coord C1 exon
chr12:113545890-113546027
Coord A exon
chr12:113545047-113545889
Coord C2 exon
chr12:113544902-113545046
Length
843 bp
Sequences
Splice sites
5' ss Seq
AAGGTGCCA
5' ss Score
3.41
3' ss Seq
CCCTCGCTTCTTTGCTCCAGGCT
3' ss Score
8.63
Exon sequences
Seq C1 exon
GATGTGAAGTACCTGGCCATCAGTGGATTTCTCTTCTTGCGATTCTTCGCACCTGCCATCCTTACCCCAAAGCTGTTTGACCTTCGGGACCAACACGCGGACCCCCAGACTAGCCGCTCACTGCTGTTGCTTGCCAAG
Seq A exon
GTGCCAGCCATGGGTTTCCCCCATCCTAGGTACTTTAGCCAGGGAAAAAAGCATGGTAGGAGCAGAGCTGGGAGGCCAGACCCACAGAAGACCCAAAGAACATCCGAAGAAACCCAAGTCTGAAACACCACCGTTAGCATTCCATCCCAAGGGTGAAGGCAGTCATCATGCACTCCAATTTCCCCTTTGGGAATGAAAACCCAACCCTTCCAGAAGGAAAGTGGAAAACAGGCTAGCAGGCATTCACACCTTAGTATGAATTAGATCATCATTTGCAAAGGGCAACAACTTGAGATTCTGCATGAGAGTACCATGGTAGGACTGAGCAGTTCTTGGGGAGGATCTGGGCTCGGGAGGGAACAGAATAAGGTTAGTGGGGAGTGCAGATTCCAAAAAGAGGAAGGGGAAACAGACATCACCCAAGGAAGGTGTTGAGTCTTCTTATTGATTTATTTTTTTCCTTGAGACAAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCACGATCTTGGCTTACTGCAACCTCTGCCTCCTCGGTTCAAGTGATCTTCCCACCTCAGCTTCTGGAGTAGCTGGATTTACAGGCGTGAGCCACCACGACCAGCTAATTTTTGCATTTTTAGTAGAGATGAGGTATCACCATGTTGGCCAGGCTCGTCACAAGCTCCTGACCTCAAGTGATCCGCTTACTTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACTGTGCCCGGCAATATGAGTCTTCTTTTATTGAGCACTGATTTGGGAGCCAGGAGGGGCCCTACCCTCTGCTGTGACCTTGGCCCCGGCATCCCTCGCTTCTTTGCTCCAG
Seq C2 exon
GCTGTGCAGAGCATTGGAAACCTGGGCCAGCAGCTGGGCCAAGGCAAGGAACTGTGGATGGCCCCCCTGCACCCCTTCCTGCTGCAGTGTGTCTCACGTGTGAGAGACTTCCTGGACCGGCTGGTGGATGTGGATGGGGATGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000111344-RASAL1:NM_004658:15
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0061614=RasGAP=FE(23.7=100)
A:
NA
C2:
PF0061614=RasGAP=PD(3.2=12.2)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGAAGTACCTGGCCATCAGTG
R:
TCATCCCCATCCACATCCACC
Band lengths:
278-1121
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)