HsaINT0137703 @ hg38
Intron Retention
Gene
ENSG00000075391 | RASAL2
Description
RAS protein activator like 2 [Source:HGNC Symbol;Acc:HGNC:9874]
Coordinates
chr1:178465920-178467421:+
Coord C1 exon
chr1:178465920-178466122
Coord A exon
chr1:178466123-178467333
Coord C2 exon
chr1:178467334-178467421
Length
1211 bp
Sequences
Splice sites
5' ss Seq
CAGGTTAGA
5' ss Score
5.94
3' ss Seq
TCCTTCCTGCCACATTCTAGGCT
3' ss Score
7.57
Exon sequences
Seq C1 exon
TATGAACAAGAAATTACTAAACTGAAGGAGCGCCTGAGAGTTTCCAGCCGGCGACTGGAGGAATATGAACGCCGCTTGCTGGTGCAGGAGCAGCAGATGCAGAAGCTGCTGCTGGAATACAAGGCCCGACTGGAGGACAGCGAGGAGCGGCTCCGAAGACAGCAGGAAGAAAAAGATAGCCAGATGAAAAGCATCATCAGCAG
Seq A exon
GTTAGACATCACCTGGCAGCAGATGTGGGCTAGTTAGCAAGACAAAGAATTGAGATGATCCACAGAACCCTGAAGGAATGGCAGCAAAAGCCATTTTTATCCTTGTGGTACTGAGTACAAATGTGATAATTGACTGTATCTCTTAAAATATCCTAAATATGAGACCTTGGGCACTTCCTATGAAGATAATCTGTTTTTCTTTAACCATAACAATTAGAAAAAATTAAAACTTGGTGGTTTACTTGAGAAATCTTAGAGGAGAACTCGGTTTTAAAAATGTAAATATCCAATGCCCAAGACTAAATTAATCTTTCAAAATAAGTCCAGAAACATGGAAAGGAATTTTATGGAATATCTTTAGGGCCAGAGGACCTCTTTTGAGAGTGCTGCAGATGCCAAGGGAGAAAAAGGGAGGGTCAGTTTTACCAAACACTTGTATAGCACTCGACATGGGACACACACCTTTCTAAGCACTTTACACATAATAGTTTGTTTAATCTTTATCACAGCCTCCACCTACGCATTATTATTCTCATTTTACAAATAAACAGGCAACAAATTCATTAAGTCACTTGCCCAAGGTCACATAGTGATGCACCAGGATTTGAATCCCGGACTCCAGATTCCATGCTCATAACCTCTATGCCTCAATATTTGTAAAATGCTATGGACAGGTCAAGTAAACAGAACTGTTTGTTGTTTTAATAGTGTGGAGGTAATTGACAGTCTTACTGAGAGGTGTTTGGGTAGACTGGCAGAATTAAACATCAATGAGTTAAGATGTGAATGGCGGACAGAAAACAAGCTAAACATACTAGGTATAGAGTACTCATTGAGGAAACTTAGCTGTGCAAGGGAAGAGAAAGTGGGCCAGGTTTAGGGTAACTTGAGATTAAGAGAGGGTTGTTTGTTTTTTGTTGGTTGATTTGATATTTTAAGATGAAATAAGTTGTGCTCAGGAAGGAATCTGAGAGAGAAGAGGGAGGAAATGATTATGGGGTTACTATTCCAAGGGAGATGAAAATGTGTGGGATCCAGGCACAAGGAGAAAAATCAACCTTAGATGTCTTATTCCAAGGTAGTAGAGAAGAAAGAAAAGATGGTTGCAGGTGTCTTATTAAAAAGGGCAGAGGATATTGAGTTTTCCTGTTCTCTACACTAGCTAGCCCTTTCTTTGAAGATGTTGATATTTCCTTCCTGCCACATTCTAG
Seq C2 exon
GCTAATGGCTGTGGAAGAGGAACTGAAGAAGGATCATGCTGAGATGCAAGCAGTTATTGATGCAAAGCAGAAAATAATTGATGCACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000075391:ENST00000462775:14
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.321 A=NA C2=0.153
Domain overlap (PFAM):
C1:
PF120043=DUF3498=FE(13.3=100)
A:
NA
C2:
PF120043=DUF3498=FE(5.8=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACAAGAAATTACTAAACTGAAGGAGC
R:
CTGTGCATCAATTATTTTCTGCTTTG
Band lengths:
286-1497
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development