HsaINT0137708 @ hg38
Intron Retention
Gene
ENSG00000075391 | RASAL2
Description
RAS protein activator like 2 [Source:HGNC Symbol;Acc:HGNC:9874]
Coordinates
chr1:178441549-178443229:+
Coord C1 exon
chr1:178441549-178441647
Coord A exon
chr1:178441648-178442674
Coord C2 exon
chr1:178442675-178443229
Length
1027 bp
Sequences
Splice sites
5' ss Seq
AAGGTAATA
5' ss Score
8.49
3' ss Seq
GCTTTGTTGCCTCTTTATAGGAC
3' ss Score
10.24
Exon sequences
Seq C1 exon
GTTACCTACTTAAGTGGAAGTAAATGCTTCAGCTGTAATTCTGCTTCTGAGAGAGACAAGTGGATGGAAAACCTTCGCAGGACAGTTCAACCTAATAAG
Seq A exon
GTAATAGTAGCTTCAAGTATCTAAAAAATGTATAACTTTGTAAGCAGTTAATTGATAGAAGGTAAGTGTGGTAGTAATACCTTAATTTGTCTATAGCTTGAGAGTTTTAAAGCACATTTATATGTTATGCCATTTGTAGTAAGCCCTTATTATATCACCATAAAGAAGTATCTGAGACTGGGTAATTTATCAAGAAAAGCAGTTTAATTGGCTCACGGTTCTGCAGGCTTTACAGGAAGCATGGTGCTGTTATCTGCTCAGCCTCTAGTAAGGCCTCAGGAAACTTACAGTCATGGCAGAAGGCAGAAGGGGAGCAGGCACATCACATGGTGAAAGCAGGAGCAAGCGAGAGAGAGAGTGTGTGTGTGAGTGACTTGGGGGGAAGGTGCCACACACTTTTAAACCACCAGATCTCACAGGAACTCAGTATCAGGAAGATGGCACCAAGGCATGAGGAATCTGCCCCCATGATCCAAACACCTCCCACCAGGCCCCACCTCTAGCACTGGGGATTACAATTCAACATAAAATTTGGGCAGGGACAACTATCCAAACTGTATTATCATTTTAAGCTAAAAGCAGTCTTACTGCAGATATTATTGCCATGGTTCTACCAGCATGGATAAAAGGACTCTGAAAAGTTAGGTGAATTGGCCATGTCAGAAGCTAGTACATGATAGAAGAGGGACTAGAATACGAGCTTCTTAACAGCTTATCTCTTTTATTTGCAGATATTAGACTGGTTATATGAAAACTTACCGTTACAAAATGATATTTTCTTAACCCAAGTAAATAAAATAGAATGAACTATATATAATATATATAATGAACTATATATAATTCTTCAAGATTCTAATGCATGCTTGTTTAGAGCTTGCTGTTAACCTAAGCAATGAGATAGCAATCCCTTTCATTATTTGTTGACTCCCCTTAATAGAGTACCTAATGAACATTGCCAACTTAAGAAAAAAATGTTTTTTTTTCTGCAATGTCAGCTCTGAAATTCAGCTTTGTTGCCTCTTTATAG
Seq C2 exon
GACAATTGCAGGCGAGCTGAAAATGTTCTTCGTTTATGGATCATTGAAGCCAAGGACCTTGCCCCTAAAAAGAAATATTTCTGCGAACTGTGCCTTGATGATACCCTCTTTGCTCGTACAACCAGCAAGACCAAAGCAGACAATATTTTCTGGGGCGAACATTTTGAATTCTTCAGCCTTCCACCTCTTCATAGTATCACAGTTCACATTTACAAGGATGTGGAAAAAAAGAAAAAAAAGGACAAGAATAATTATGTAGGGCTAGTCAACATCCCCACTGCCAGTGTGACTGGTCGCCAATTTGTAGAAAAGTGGTATCCAGTGAGTACACCTACACCCAACAAAGGAAAGACAGGAGGACCTTCTATTCGGATTAAATCACGTTTCCAAACTATCACCATTCTGCCTATGGAGCAATACAAAGAATTTGCAGAATTTGTCACCAGCAACTACACCATGCTGTGTTCTGTCCTTGAGCCAGTAATTAGTGTGAGAAATAAAGAGGAGTTGGCTTGTGCCTTAGTGCACATTCTTCAAAGTACTGGCAGAGCCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000075391:ENST00000462775:5
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.121 A=NA C2=0.049
Domain overlap (PFAM):
C1:
PF0016924=PH=PD(12.4=87.9)
A:
NA
C2:
PF0016825=C2=WD(100=43.2)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGATGGAAAACCTTCGCAGGA
R:
ACAAATTGGCGACCAGTCACA
Band lengths:
343-1370
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development