HsaINT0139635 @ hg19
Intron Retention
Gene
ENSG00000092871 | RFFL
Description
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:24821]
Coordinates
chr17:33336131-33341782:-
Coord C1 exon
chr17:33341759-33341782
Coord A exon
chr17:33339169-33341758
Coord C2 exon
chr17:33336131-33339168
Length
2590 bp
Sequences
Splice sites
5' ss Seq
ACGGTATGT
5' ss Score
9.94
3' ss Seq
TGCCCTGTGTGTTTGTACAGGGG
3' ss Score
8.77
Exon sequences
Seq C1 exon
TCAGTGGTGCCGAAGACCAAAACG
Seq A exon
GTATGTAGTTGTTTCTGTTTGGGAATGGGCTTAGGCCCTTTTGTCCTTCCCCTCCTTCAACCCCAATCCCTTTAGTAATCTAAGAATTCTGAGCATTTGAGCCCCCAGAGAGAGGGTGTGTGGGAAACTCACTGAGACCCAGGGGGCCTCTCACCATCTTTAGAAATTCTCTCTGCTCGCTGTGCAGGAAGCAGAGTGGAGCATACGTAGGGGCGGACTGACTGATGTGCATGTCCCTGGGCTACCTGAGCTCATAAGCCAACATTTGTAAAACACTGAAACAGAGGAGGGGTGGCATGTATCACACTCAGCTCATTTTTTAAAATCTTGGTGTTTTCAGTTCTGGTCTGGGTAGGGAGGGTCTCTGTGTACACCTTCTGGGGAATCAGGGTGTTTAGCAGCTTCTGGTACTAACCAAAAAGAAAGGGTGGTGACCTGAGACAGCCCTGTTTGTACAGGGCTGGTAATGGTTAGAGCTACTCTGGAGCTAACACATGTGCTACTCTCTGGGCACAAGCTATATATCTCAGCTCAGCTGCCACTCACTTAAAGACCACCACTGGGCCCTCAGGTACTCCCAGAACACACTGCAGAACTCCTGACCATCTGTGGGGACATTCTAAAATATGCTATGTGTTTTCAAAAGCCTCAAGGGTATATGGTTGTGAACTCCCTTCCAAGAGAGAACGTTCTAAGAGTAGTGTTGGACTAGCCTGCAGCATTTTAAAACTTATTTCAGAAGATTTCCCAAATTTATTTAGTAAAATGGCCTTTTGCTCAGAATGGGCAATTTTATGTCTGATTACTTCTAATCAGACATAAAAAACAGTTGAGCTTTTCTCAATTCCCCAAAACCATTTGGAGTTCTAGACCCACCTCCACCCTCCAACCCCCCAGCATCACCGGTACCAAGATCAGGCTGATCTACTTGGTGCTTCCTTTCTTTTTCTGATTCCCTGGGAGAATGCTGACAACTGAGTTAATGTGTTTGTTGTTACTTCTGAGAGAATGAGTAACTGAAAATTATAAATTATTCCCATTCATCTTAGGTATTTGTATAGTCTCCAAACCTCTGTTAGGACCAACAGCACCTCAAAAGAGGCAAATGGGTTTCACTCCCTTTCACACCCAGCCTACCTCCTAGGGGGAAGTATTTCTTGACTTTTTAATAGTCCAGAAAAGAGAAAGTATAGATGCAATAAGGGAGAATTCCTCTATGGGTTGGCCAACCCCCAGATGGTAGAGGTGACTTCTGTGAGATCAGTTCCTTTTTATGGGTACCTACTTCAGGCTACAATTTAAGACATATTGGAGATGGCTGGGCTTTTGAACATTATTTTTTCTGTTTGGGTCAGCTCTACTAGGATACTGGTCATGCCCACTATATTCTGCTAGTGACACAAGCCAGTTAGCATTTATTGAGAACCCTGTGCACTCAGCAGTTGATACTGTCTGGATAGTTTCTACTCTTAGGGCAGTTAGGCAGAAGGCCATTCTAGAGCAGGAGCTGTGGGGCCAGCCTGCCTGGGTTTGAATCCTGGCTCCTCGACTTAGCAGCTTTGTGCCCTTGGGCAAGCCACTTAACTTTTTTGCCCCAGTTGGCCTCATCTATAAAATGAAAATAACAAGAGGTCCTACTTTATAGTTTTTGTGAGGCTTCAGTGAGTTAACACATGCAAAGCTTTCAGGACCCTGCCTGGCACACGGTAAGCATTCAGTAAATGTGGGATGTTGTCATTCCCTTGGGAAGATGTTCATTCATCAGACATTTAGAGTACCTACCATATAACTGGCATTGGGGGCTTCAAAGATGAATATCTAACCTTGGAGCATGGAATAAATGCTAAGCATATAATTGTAAAAATTGATTGAATATGTTGAATTAAAGAGCTCATAGTCTACTCTGGGAGTAAGTAGGCAAACTCAAAATTTTAATCCAATGTGATAAGCAGTCATGGGGGTATAAAAAAGTTTTGTGGGGGTAGAAAGAGGGAGCAGTAATCTCTGCCAAGTTTCTCCACCAGGAAGTTTCCTCAGGAAACCTGGGAGTAGTTTGTGAGATAGCAGAGGGGTCCCCCATGATCCCTGACTTTATTAAATGGAGGATATGTTTATAGATAAAGCCTTGTGATCCTTAATGAACCATTCATCACAGTTCCATTTCTATCTAAACTTTTCTGAACCAGTTTTATCTTTTTAGCCTGTTCTGCCTCAGGGGATAATGAGTCCCTACGTGCCACTCACACACTCACTATATTACAGCCCCAACAGTCTGAAAATTATTTCTTTTAAGCTTTGAGAACTTTGCCTTAGTTCTCATGTTCTGGGATGTGTCTGATCCACAAGTGCTGTGTACTTTTCAAATCTTTACCTGTTGGAGGGGATGAAGTGTGGATTAAACAAGTAACCAGAGTTGGTTATTGAGGAAATGTTTCCTCGGAGGAGCTCTATTTGAGGGAAGCATGTGCACTGAGACTTTGTTTACAATGTACCTGTTATCTCCCACCTCCCTCCCCCAGTCACCCCTATACACTTAAGACATTCTCCTCACTCCTCTGCCCCTTTTTTTCTGCCCTGTGTGTTTGTACAG
Seq C2 exon
GGGGAGCAGTACCATCAGGCTTGGAGGAGAACCTGTGTAAGATCTGCATGGACTCACCCATTGACTGTGTTCTTCTGGAGTGTGGCCACATGGTAACCTGTACCAAGTGTGGCAAGCGCATGAATGAATGTCCCATCTGCCGGCAGTATGTAATCCGAGCTGTGCATGTCTTCCGGTCCTGAGAGCTTGCATCGGTTTCTTCAGTGCCTTACAGGGAAATAGCCTGGGGTGTCTGGGCTCAGGGTTGGCCAGCTTGCAGAGGAGCAAGCTAGTAGAAATATTGCAGGGTTCCCAAAACCAGGTCAAGCAAGATGCCATGTCACCCCTGAGCATGCCTGTCTTCCCAGGGGTGTACCTCTTGGCTGGCAAAGCCCAAGGCCAGTGGGAACTTGTATAAATCACATGGGTATGTTCTTGGTTCAGTGATCTTGGAGTGATGATGGTAACTGATGAACAGAGAACTTTCCAGAACTTGGGTCCTGTCTTCCTCCCTGAACCTAGACAGTTTCACCCCTCCTCCTGTACCCAACCCATCCCCACCCCATATGGGAGATGCTTGCCCATGTGTTTCATCAATCAGAAGTCCTCCTCCCCAGCACATTCGGATTTAAATTTCTGGTCTCTCCGGCTTTCTGTGCTTTAACTATCTTTGCTAAAGTCTCTTGCTACATTGCCTAAATCCATTTGTTTCTTTGGACCAAAAATGTTAGTTTACCAGACCGATAGTGGTCCTTAGGACAGATTTTAGACCAGTAAACTTATCTTTGGTGAGAAATGAAATACAAATGCTATAGAAAAATTTCAAAGTTGTTAAAAGCCACTTCATTAAATGCTGGGATTGGAAGCTGTTGGTCTCCTGACCTGACTCTGGGAGCCAACAAAACATCAGGCTCCCAAACTGCTGGGAAATTTGTTTCTGTCTGCAAGGGATAGTGCGTGCATAATCCCTGCTGCTGCTTCTCTTGGGACCTGATTTGCACCATCCTTAGTTTATGCGGAAAGGGGAAGCAATGGGTGGAGGCAGTGGCCTTCTCCTTAATTTTGGCTTGGCTTCTGATCCTTTTCCCAACTAGAAGTCTTAAGCCACTTTTCGCTGAAAATGAAATCCCTCCCTTATCCATGGTAGTTTTAAATTTGGTTTCATTGAAGAAATAGATTTAGGCAAAGAGCCTGTGCTCTTCTCTGGCCAGACTGCTGTTGAAGTTCCTGGAGAGCAAATGTTAAGACAGAGCACTTAAGAGCTTTCAGGAGGTACTGAATGAGACTGGATTCTGTTGTAAGCCGACAGTTCAAGTCTTTATTTCCCAGGTTGGTGGGGAGTGAGGAGACCCTACTTTCATTCCCTTTCCTAGCCCACTGATTTTTGGGGGCAGGTCAGGGAGAAAGCATTTTTTTTTTTTTTTTGAGTCTCACTCTGTTGCCCAGGCTGGAGTGCAGTGGTACAGTCTTGGCTTACTGCAACCTCCACCTCCCAGGTTCAAGCTATTCTCCTGCCTTAGCCTCCAGAGTAGCTGGGATTATAGGCGCCCACCACCACACCAGGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTTACCATGTTCACCAGGCTGGTCTTGAACTCTTGACCTTATGATCCGCCCGCCTCAGCTTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCACACCCAGCAGGAGAAACCATTTTCTAGGCTCTTTAGGAAGGACCATGCAATGAGTAGGTGATGTATTTGAGCCCTCACAGTCTTTACACCCCTAGAGGAGCTGGAGGACTTAAGAGTTTGCTGCAGAAGCGTGGCCAAGCACAAAACACATGATCAGGAAAGCAGAGTGTTTTCCCATTACCAATGGATGAACTATGCAAACCCTAAACGCCTTGGCAGACACCTCCCACCCCTTACCCCTCCCATGCAGCTGAAAAATCTGAGACTAGAACCAATCATGACTCTGGATGGCAGAGGGAAACCTCTAAAGGGACTTATTACATTGGTACAGACATATTTATGCTTTCTTCCATCACCAACCACTAAACCCCTTTGGAGGAATGAAATAACTGCATAAACTAGTCAACTGAACACTGGGCCACTTACCTCAATGTTATACAAAGTCCTGGATGATTTGATTCTGAACCACAGCCTTTGCAGGAGTTGGGGGAATCAGATTTGCTCATGAAGACATCCCTTTCCACTTTTGTCATGGGCAGTAAATACTATAGTTTACAATGCCTACCAATTAGCAAAGGATCATTCATTCAGCTACTCAGTTCCTCTGTAAAACAGGTCTATGTATGTGCAATTCAGCTAAGATCTAGCAGTAACTTAAGGGCAGAAGCTGGCTCTCTACTTACAACCTGCTTTCTCTGCTGAAGCCTTACCTCCTCTTCAGTTTCCCTCCTAGACACAAATCGAAAATAATATACTGATAGCTGGTTAGTAACCTCAGTAAGAATTAAAACTGAGGTTGTTTACTCATTTTGCCTTTAAATCTTTTATCCCCTTTTGGTGAAGGTTTCCCTTTAGGAAAAAAGGTGTCAAACAACCCTGATTTTTTTTTTTTTTGCATCATTTTTATTACACCAAATTAAAGTTGGGAGTTCCAAGATCCCATTCCAGTTAATATTTAACCAAGGTCTAAAATTTGATTTTTTTTAAATCTTTGAATCCTCCCTTCTGCCCCTCATGGATCCTTGGTTTTAATGATATGGAAACATCTAATTCTTAGAATTATTCCGTAGCTTTTGCTGATTACTCTGAGATTTCAGTTAAGACTTGTTTCAAAAGACAGATAGCTGACTGGTTCATAATACATTGGAATAGTTGGATCCAAACTAATAAGAATAAGCTGTACAGGAACTAGTGCTCAATATACATTGTATAAATTTGTGGAAATCTCTTGGATGTGAATTGTTACTTCAAGTGGCTTTTATTAAGATTTTCTCAGACTTACTTGGAGGTTAAAGCAAACCCAAATGTGTATTATTTTGTTACAGAGCTCTGCTTTATAATTTTGTAATAAAGTTTCAATACAGACACC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000092871-RFFL:NM_057178:6
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.333 A=NA C2=0.007
Domain overlap (PFAM):
C1:
PF102084=Armet=PD(5.0=55.6)
A:
NA
C2:
PF139201=zf-C3HC4_3=WD(100=75.4)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)