HsaINT0139635 @ hg38
Intron Retention
Gene
ENSG00000092871 | RFFL
Description
ring finger and FYVE like domain containing E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:24821]
Coordinates
chr17:35005990-35014763:-
Coord C1 exon
chr17:35014740-35014763
Coord A exon
chr17:35012150-35014739
Coord C2 exon
chr17:35005990-35012149
Length
2590 bp
Sequences
Splice sites
5' ss Seq
ACGGTATGT
5' ss Score
9.94
3' ss Seq
TGCCCTGTGTGTTTGTACAGGGG
3' ss Score
8.77
Exon sequences
Seq C1 exon
TCAGTGGTGCCGAAGACCAAAACG
Seq A exon
GTATGTAGTTGTTTCTGTTTGGGAATGGGCTTAGGCCCTTTTGTCCTTCCCCTCCTTCAACCCCAATCCCTTTAGTAATCTAAGAATTCTGAGCATTTGAGCCCCCAGAGAGAGGGTGTGTGGGAAACTCACTGAGACCCAGGGGGCCTCTCACCATCTTTAGAAATTCTCTCTGCTCGCTGTGCAGGAAGCAGAGTGGAGCATACGTAGGGGCGGACTGACTGATGTGCATGTCCCTGGGCTACCTGAGCTCATAAGCCAACATTTGTAAAACACTGAAACAGAGGAGGGGTGGCATGTATCACACTCAGCTCATTTTTTAAAATCTTGGTGTTTTCAGTTCTGGTCTGGGTAGGGAGGGTCTCTGTGTACACCTTCTGGGGAATCAGGGTGTTTAGCAGCTTCTGGTACTAACCAAAAAGAAAGGGTGGTGACCTGAGACAGCCCTGTTTGTACAGGGCTGGTAATGGTTAGAGCTACTCTGGAGCTAACACATGTGCTACTCTCTGGGCACAAGCTATATATCTCAGCTCAGCTGCCACTCACTTAAAGACCACCACTGGGCCCTCAGGTACTCCCAGAACACACTGCAGAACTCCTGACCATCTGTGGGGACATTCTAAAATATGCTATGTGTTTTCAAAAGCCTCAAGGGTATATGGTTGTGAACTCCCTTCCAAGAGAGAACGTTCTAAGAGTAGTGTTGGACTAGCCTGCAGCATTTTAAAACTTATTTCAGAAGATTTCCCAAATTTATTTAGTAAAATGGCCTTTTGCTCAGAATGGGCAATTTTATGTCTGATTACTTCTAATCAGACATAAAAAACAGTTGAGCTTTTCTCAATTCCCCAAAACCATTTGGAGTTCTAGACCCACCTCCACCCTCCAACCCCCCAGCATCACCGGTACCAAGATCAGGCTGATCTACTTGGTGCTTCCTTTCTTTTTCTGATTCCCTGGGAGAATGCTGACAACTGAGTTAATGTGTTTGTTGTTACTTCTGAGAGAATGAGTAACTGAAAATTATAAATTATTCCCATTCATCTTAGGTATTTGTATAGTCTCCAAACCTCTGTTAGGACCAACAGCACCTCAAAAGAGGCAAATGGGTTTCACTCCCTTTCACACCCAGCCTACCTCCTAGGGGGAAGTATTTCTTGACTTTTTAATAGTCCAGAAAAGAGAAAGTATAGATGCAATAAGGGAGAATTCCTCTATGGGTTGGCCAACCCCCAGATGGTAGAGGTGACTTCTGTGAGATCAGTTCCTTTTTATGGGTACCTACTTCAGGCTACAATTTAAGACATATTGGAGATGGCTGGGCTTTTGAACATTATTTTTTCTGTTTGGGTCAGCTCTACTAGGATACTGGTCATGCCCACTATATTCTGCTAGTGACACAAGCCAGTTAGCATTTATTGAGAACCCTGTGCACTCAGCAGTTGATACTGTCTGGATAGTTTCTACTCTTAGGGCAGTTAGGCAGAAGGCCATTCTAGAGCAGGAGCTGTGGGGCCAGCCTGCCTGGGTTTGAATCCTGGCTCCTCGACTTAGCAGCTTTGTGCCCTTGGGCAAGCCACTTAACTTTTTTGCCCCAGTTGGCCTCATCTATAAAATGAAAATAACAAGAGGTCCTACTTTATAGTTTTTGTGAGGCTTCAGTGAGTTAACACATGCAAAGCTTTCAGGACCCTGCCTGGCACACGGTAAGCATTCAGTAAATGTGGGATGTTGTCATTCCCTTGGGAAGATGTTCATTCATCAGACATTTAGAGTACCTACCATATAACTGGCATTGGGGGCTTCAAAGATGAATATCTAACCTTGGAGCATGGAATAAATGCTAAGCATATAATTGTAAAAATTGATTGAATATGTTGAATTAAAGAGCTCATAGTCTACTCTGGGAGTAAGTAGGCAAACTCAAAATTTTAATCCAATGTGATAAGCAGTCATGGGGGTATAAAAAAGTTTTGTGGGGGTAGAAAGAGGGAGCAGTAATCTCTGCCAAGTTTCTCCACCAGGAAGTTTCCTCAGGAAACCTGGGAGTAGTTTGTGAGATAGCAGAGGGGTCCCCCATGATCCCTGACTTTATTAAATGGAGGATATGTTTATAGATAAAGCCTTGTGATCCTTAATGAACCATTCATCACAGTTCCATTTCTATCTAAACTTTTCTGAACCAGTTTTATCTTTTTAGCCTGTTCTGCCTCAGGGGATAATGAGTCCCTACGTGCCACTCACACACTCACTATATTACAGCCCCAACAGTCTGAAAATTATTTCTTTTAAGCTTTGAGAACTTTGCCTTAGTTCTCATGTTCTGGGATGTGTCTGATCCACAAGTGCTGTGTACTTTTCAAATCTTTACCTGTTGGAGGGGATGAAGTGTGGATTAAACAAGTAACCAGAGTTGGTTATTGAGGAAATGTTTCCTCGGAGGAGCTCTATTTGAGGGAAGCATGTGCACTGAGACTTTGTTTACAATGTACCTGTTATCTCCCACCTCCCTCCCCCAGTCACCCCTATACACTTAAGACATTCTCCTCACTCCTCTGCCCCTTTTTTTCTGCCCTGTGTGTTTGTACAG
Seq C2 exon
GGGGAGCAGTACCATCAGGCTTGGAGGAGAACCTGTGTAAGATCTGCATGGACTCACCCATTGACTGTGTTCTTCTGGAGTGTGGCCACATGGTAACCTGTACCAAGTGTGGCAAGCGCATGAATGAATGTCCCATCTGCCGGCAGTATGTAATCCGAGCTGTGCATGTCTTCCGGTCCTGAGAGCTTGCATCGGTTTCTTCAGTGCCTTACAGGGAAATAGCCTGGGGTGTCTGGGCTCAGGGTTGGCCAGCTTGCAGAGGAGCAAGCTAGTAGAAATATTGCAGGGTTCCCAAAACCAGGTCAAGCAAGATGCCATGTCACCCCTGAGCATGCCTGTCTTCCCAGGGGTGTACCTCTTGGCTGGCAAAGCCCAAGGCCAGTGGGAACTTGTATAAATCACATGGGTATGTTCTTGGTTCAGTGATCTTGGAGTGATGATGGTAACTGATGAACAGAGAACTTTCCAGAACTTGGGTCCTGTCTTCCTCCCTGAACCTAGACAGTTTCACCCCTCCTCCTGTACCCAACCCATCCCCACCCCATATGGGAGATGCTTGCCCATGTGTTTCATCAATCAGAAGTCCTCCTCCCCAGCACATTCGGATTTAAATTTCTGGTCTCTCCGGCTTTCTGTGCTTTAACTATCTTTGCTAAAGTCTCTTGCTACATTGCCTAAATCCATTTGTTTCTTTGGACCAAAAATGTTAGTTTACCAGACCGATAGTGGTCCTTAGGACAGATTTTAGACCAGTAAACTTATCTTTGGTGAGAAATGAAATACAAATGCTATAGAAAAATTTCAAAGTTGTTAAAAGCCACTTCATTAAATGCTGGGATTGGAAGCTGTTGGTCTCCTGACCTGACTCTGGGAGCCAACAAAACATCAGGCTCCCAAACTGCTGGGAAATTTGTTTCTGTCTGCAAGGGATAGTGCGTGCATAATCCCTGCTGCTGCTTCTCTTGGGACCTGATTTGCACCATCCTTAGTTTATGCGGAAAGGGGAAGCAATGGGTGGAGGCAGTGGCCTTCTCCTTAATTTTGGCTTGGCTTCTGATCCTTTTCCCAACTAGAAGTCTTAAGCCACTTTTCGCTGAAAATGAAATCCCTCCCTTATCCATGGTAGTTTTAAATTTGGTTTCATTGAAGAAATAGATTTAGGCAAAGAGCCTGTGCTCTTCTCTGGCCAGACTGCTGTTGAAGTTCCTGGAGAGCAAATGTTAAGACAGAGCACTTAAGAGCTTTCAGGAGGTACTGAATGAGACTGGATTCTGTTGTAAGCCGACAGTTCAAGTCTTTATTTCCCAGGTTGGTGGGGAGTGAGGAGACCCTACTTTCATTCCCTTTCCTAGCCCACTGATTTTTGGGGGCAGGTCAGGGAGAAAGCATTTTTTTTTTTTTTTTGAGTCTCACTCTGTTGCCCAGGCTGGAGTGCAGTGGTACAGTCTTGGCTTACTGCAACCTCCACCTCCCAGGTTCAAGCTATTCTCCTGCCTTAGCCTCCAGAGTAGCTGGGATTATAGGCGCCCACCACCACACCAGGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTTACCATGTTCACCAGGCTGGTCTTGAACTCTTGACCTTATGATCCGCCCGCCTCAGCTTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCACACCCAGCAGGAGAAACCATTTTCTAGGCTCTTTAGGAAGGACCATGCAATGAGTAGGTGATGTATTTGAGCCCTCACAGTCTTTACACCCCTAGAGGAGCTGGAGGACTTAAGAGTTTGCTGCAGAAGCGTGGCCAAGCACAAAACACATGATCAGGAAAGCAGAGTGTTTTCCCATTACCAATGGATGAACTATGCAAACCCTAAACGCCTTGGCAGACACCTCCCACCCCTTACCCCTCCCATGCAGCTGAAAAATCTGAGACTAGAACCAATCATGACTCTGGATGGCAGAGGGAAACCTCTAAAGGGACTTATTACATTGGTACAGACATATTTATGCTTTCTTCCATCACCAACCACTAAACCCCTTTGGAGGAATGAAATAACTGCATAAACTAGTCAACTGAACACTGGGCCACTTACCTCAATGTTATACAAAGTCCTGGATGATTTGATTCTGAACCACAGCCTTTGCAGGAGTTGGGGGAATCAGATTTGCTCATGAAGACATCCCTTTCCACTTTTGTCATGGGCAGTAAATACTATAGTTTACAATGCCTACCAATTAGCAAAGGATCATTCATTCAGCTACTCAGTTCCTCTGTAAAACAGGTCTATGTATGTGCAATTCAGCTAAGATCTAGCAGTAACTTAAGGGCAGAAGCTGGCTCTCTACTTACAACCTGCTTTCTCTGCTGAAGCCTTACCTCCTCTTCAGTTTCCCTCCTAGACACAAATCGAAAATAATATACTGATAGCTGGTTAGTAACCTCAGTAAGAATTAAAACTGAGGTTGTTTACTCATTTTGCCTTTAAATCTTTTATCCCCTTTTGGTGAAGGTTTCCCTTTAGGAAAAAAGGTGTCAAACAACCCTGATTTTTTTTTTTTTTGCATCATTTTTATTACACCAAATTAAAGTTGGGAGTTCCAAGATCCCATTCCAGTTAATATTTAACCAAGGTCTAAAATTTGATTTTTTTTAAATCTTTGAATCCTCCCTTCTGCCCCTCATGGATCCTTGGTTTTAATGATATGGAAACATCTAATTCTTAGAATTATTCCGTAGCTTTTGCTGATTACTCTGAGATTTCAGTTAAGACTTGTTTCAAAAGACAGATAGCTGACTGGTTCATAATACATTGGAATAGTTGGATCCAAACTAATAAGAATAAGCTGTACAGGAACTAGTGCTCAATATACATTGTATAAATTTGTGGAAATCTCTTGGATGTGAATTGTTACTTCAAGTGGCTTTTATTAAGATTTTCTCAGACTTACTTGGAGGTTAAAGCAAACCCAAATGTGTATTATTTTGTTACAGAGCTCTGCTTTATAATTTTGTAATAAAGTTTCAATACAGACACCTGTCCTGTCTGGTGCGAGGATGTTAGAGGTTGATAGGACTGACAAAAGAGCCTGACAGTGGTTCATGCTATAATTTCCACACTTTAGGAGGCCAAGGTGGGAAGACTGCTTGAGCTCAGGAGTTTGAGACCAACCTGGGCAATGTAGTGAGACCTTGTCTCTACTTAAAAAAACAAACAAGGGCCGGGTGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGCAGATCACGAGGTCAGGAGATCGAGACCACCCTGGCTAACACGGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCCAGGCGTGGTGGCGGGTGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGTGTGAACCCGGGAGGCGGAGCTTGCAGTGAGCCAAGATTGCGCCACTGCAGTCCGGCCTGGGCGAAAGAGCGAGACTCTGTCTCAAAAAACAAAACAAAAAAAAACACAAACAAAAAACCCAAAAAAACCAAAAAATTAGCCGTGCATGGTGGTGCATGTGGGTAGTCCCAACTACTTGGAAGGCTGAGGTGGGAGGATCACTTGAGCCAGGAGATTGAAGCTGCAGTGAGCTCTGATCGCCACCGCACTCCAGCCAGGGTGACAGAGTGAGACCCTGTATTAAAAAAAAAAAAAAATTGACAACTGATAAACCACAAGCTAATCCTGGGATGTGCACATGGCCTGGGATTAGCCTGTGGTTGGGCCAAGTGACCTTGGTCAAGATGCTCAGTGTTGTTGTAACTAACTAACTTGCTCAAGACCACAAATGTAATATATGGAAGAGGCCATGGAACAACCTAGAAGAGAATGAGAGCTGGGTAGGTAAAGGATGAATCCCAAGACCAATTGGGTTGAAGCACCAAGTGAGTTCAGATATTTACACTGATCTAGAAGAGATGGGCCTTAAAGAACTGAAATCTGAGGACAGTTAGTATGCCCAGTTAGGTCTTCAGGTTACCCTGGGAGATACATGGTACCTTTTGGATACAGCTGTAGTACAGCTGGACTATGGCTCAGAAAAGGTTGGCCCAGGCTGGGCGCCATGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGTGCGTGGATGACTCGAGGCCAGGAGTTTGAGACCAGTCTGGACAACATGGCGAAACGTGGTCTCTACTAAAAATACAAAAACTTAGCTGCGAGTGATGGTGTGTGCCTGTTTGTTAAGTCTTAGCCACTTGGGAGGCTGAGGCATGAGAATTGCTTGTGAACCCGGGAAGCAGAGGTTGCAGTGAGCTGAGATTGCACCACTGCACTCCAGCCTGAATGACAGAGCAAGAGTCTGTTTAAAAAAAAAAAAAAGGTTGGCCCAGCCTCGTGACAGACTGCTGTGTGTGCGCAGGCTTGTACAAACCTCCCTGACCAGGCGCCCAAGGAGCAGGGAAAAGACTACTGAGAATGCAGCCCCTGGGAGAACAAGATTATGTGTCCATCTGCTGTGACTGAGAAGAGAAAGGAATCTTGCCAAAAGGGCATAAAGGATCGAGGATGAGCCACAACACTTTGCTCACATTGCCCTAGGGAGCTGACCTGTTCAGCACCCAGTGATGACCTCTGCTTGATGCCAGCCAGCAGCATGTAGAGGTTCAGAAGAGGGAGGCCTCCAGCATTCTGCTGGAGAGATTTATGATGATGATGTTGAGGGCTGCATTGAAATACATGAAAGAAATACATGAAAGGATACAAAATAGTATATACAGTCAGATCTCAGCAGCAAAGACTGGAAGAAAATACATAAAAAACCACTGACATTGAAATGGCAATAACACACACTAAGGCAGAGAAGGGACAAGATGATCACCTGCAGCCAGCAGAGGCCCTTTCCTGTGAGTGTGCACTCTGGGTGTAAGCAACCAATAAGGGCAAGTGGGGCTGGGTCCAGGTTGGAGAGGACAGTGCCTTTGGCAGGATCCTGAGGAGACAGCCTTGTTCTGCTGCCCTGTCCGGTTGTTTGTTTGGCCTGAGGCTGAAGAGAGAAATGGAAATCTATGTAGGTCAGTACTCAAAGGAGGAGCAGCTTTTTGTCTCCATAGAGGATGGAATAAAAAGTATCTTATTCCTAATACTGAAGCAAGGCTGAATGGTGCCTATTCAAAAACACCAAATGTCCTGGGCTAGAGTCAGGAAAGTAAACCCCTCCCCCGTGCTGTCCCTACTCCCCCAACATACACATTTTAAACAGTAGGTGGAAGCCAAAGTCAATCAGATCAAAGTTGGGGGGGGGCGGTGGGGTGGCCAGGGGGCGCAGTGGTCCTTGATCTTATAGGTCCAGAGCCTGTTAATTTGTTCATAAGGTGAGAACTGACCCTCAAGAGCTGGAAGGATTGGGACATGGCAGCCAGTTTACAACCATATGGTGTCCTGATGAGCCTGCACTCAGAGTGGAGTGTTGGCTGGAACATGCACACCTGCAACTGAGGGTTCTAAAGTCATAGGTTAGGCCCTTCTCCCGGGTAGGGTCTGGACATGCACACCAGGAGTGACGTTCCCAACTCTAGATAACTATGTGCTAGGCTCTGGGCTAAGTGCTTTACATAATGTTGCTCAGGACAACAGGACAACCCTATGATTTAGGTGCACCCATTCTACTTGGAGGGATTGAGGCTTAGATGTTAACGTAACTTGCCTAAGGTTAGAGCCATTAAGTTTCAGGAGTCTGATCTGAACTCCGTCTACACCTGCACTGTCCAGTGTGGTAGTCACTAGTGACATGTGACCATTTGAAGTTGAATTAAAATAAGAACTTCAGTTCCTTAGTTGTGCCAGCTTCATTTCAATTGCTCAGCAGCTGTCTGTGGCTAGTTTGGTTGGATACTGCAGATTTATGGATATTTCCACTGCTGCAAAAAGTTCTATTGAATAGCACTTGTCTACACTAAATTGTCTCTCTTCCTTTTGTTCTTCAAATAAATCAGCCTCAGGTAGCACAGGAGCTGTTCTTTGTAAGCAGGTTGTATGGATCTGTTCTCAGGTGTGGATTTTTATTTTTTTCCCTGCAGATATGGAGTATATTTTCTTTAAGAAATTAAAAACTAAGAAGAAAATGCCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000092871:ENST00000315249:6
Average complexity
IR
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.341 A=NA C2=0.013
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF139201=zf-C3HC4_3=WD(100=75.4)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development