HsaINT0146220 @ hg38
Intron Retention
Gene
ENSG00000146197 | SCUBE3
Description
signal peptide, CUB domain and EGF like domain containing 3 [Source:HGNC Symbol;Acc:HGNC:13655]
Coordinates
chr6:35242204-35242780:+
Coord C1 exon
chr6:35242204-35242320
Coord A exon
chr6:35242321-35242621
Coord C2 exon
chr6:35242622-35242780
Length
301 bp
Sequences
Splice sites
5' ss Seq
CAGGTTTGG
5' ss Score
5.63
3' ss Seq
TGACAAGCCCTCTCTCCCAGGTG
3' ss Score
6.46
Exon sequences
Seq C1 exon
AGGCTGCAGTGCTGTCCATTAAACAACGGGCCTCCTTCAAGATCAAGGATGCCAAATGCCGTTTGCACCTGCGAAACAAAGGCAAAACAGAGGAGGCTGGCAGAATCACAGGGCCAG
Seq A exon
GTTTGGACTGGGGACCCCATTCCAGTTGGCTGTCTGGCCACTAAATCCTCCTTACCCCTCAGCTCCTCTGCTTCCAAAAACCCACCAGAACCCTGAACTCTAGGCAGAGCAGAGGAAAAAGCAGCTGTAGGCATAGCACCCAAGGAAGTCCCAGAATATTCCCCTCCACCAACTAATTAGGACCCTAGACTAAAACAGGATTGAGAGATAGTTACAGTTAGAGATCTGGGGAGGTCTGTCTGGGCTGGGAGTGAGAACTTTCCAGGGGATGTCCCTGGGGTTGACAAGCCCTCTCTCCCAG
Seq C2 exon
GTGGTGCCCCCTGCTCTGAATGCCAGGTCACCTTCATCCACCTTAAGTGTGACTCCTCTCGGAAGGGCAAGGGCCGACGGGCCCGGACCCCTCCAGGCAAAGAGGTCACAAGGCTCACCCTGGAACTGGAGGCAGAGGTCAGAGCCGAAGAAACCACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000146197:ENST00000274938:13
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.200 A=NA C2=0.444
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGCTGCAGTGCTGTCCATTAA
R:
GTGGTTTCTTCGGCTCTGACC
Band lengths:
273-574
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development