HsaINT0166146 @ hg19
Intron Retention
Gene
ENSG00000114126 | TFDP2
Description
transcription factor Dp-2 (E2F dimerization partner 2) [Source:HGNC Symbol;Acc:11751]
Coordinates
chr3:141692890-141697524:-
Coord C1 exon
chr3:141697362-141697524
Coord A exon
chr3:141693037-141697361
Coord C2 exon
chr3:141692890-141693036
Length
4325 bp
Sequences
Splice sites
5' ss Seq
TCGGTATGT
5' ss Score
9.22
3' ss Seq
TCAGTGAAAATATTTTTTAGCAG
3' ss Score
2.66
Exon sequences
Seq C1 exon
TAAACGAAGCAAAAAAGGAGATAAAAATGGGAAAGGCTTGAGACACTTTTCAATGAAAGTGTGTGAGAAAGTTCAACGAAAAGGTACAACATCGTACAATGAAGTCGCTGATGAGCTGGTGTCAGAGTTCACCAATTCAAATAACCATTTGGCTGCTGATTCG
Seq A exon
GTATGTAAATCATGAACCTGACATTGATTTTGATGGATGATGCTACTTCTTTGTGTTATCTTTGTTATAGATTTGAGGAATCACGACTATACTTGAGGGTTTTATCCTTTATTTTGGGGGATTTTTTGTTGTTGTTGAGTTTTATTTTGGAGGGAATTCCTTTTTTTTTGTTTTTTAGGCGGAACCTCACTCTGTCGCCCAGGCTGGAGTTCAGTGGCGCGATCTCGGCTCACTGCAACCTCTGCCTCCCAGGTTCAAGCTATTCTTGTGACTCAGCCTCCCGCGTAGCTGGGATTACAGGCGCACACCACCATTCCCAGCCAATTTTTGTATTTTTAGTAGAGACAGTGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAGGTGATCCACCTGCCTTGGCCTTCCAAAGTGCTGGGATTACAGGCGTGAGCCACTGTACCCAGCCTTAGTTGTTTTTTTTGTTTTTTTTTGTTTTTTTTTAACATTTAAAAAATATTTGGCCAGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGTCTGAGGTGGGTGGATCATGAGGTCAGGAGATCGAGACCATCCTGGCTAACACTGTGAAACCCTGTCTCTACTAAAAATACAAAAAATTAGCCAGGCATGGTGGCATGTGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATTGCTTGAACCTGGGAGGCGGAGGTTGCAGTAAGCCAAGATCGCACCACTGTACTCCAGCCTGGGCGACAGAGTGAGACTCCGTCTCAAAAAGAAAAAAAAAATTGGTCGCCTATCCAATAATTTTTTATTGTTTCTGAATCTTATTGTTTCTTCAATGTCTAAGTCAACAAGAAAATTTTATTTTTAATTGGAAAAGGAATACATAAATATGTTTATAAAAAATTCAGTTGTCTGGCAGAGTCTCAAATAAATGGAATACAGTGGTGCAGTTTCGGCTCAATGAAACCTCTACTTCCCAGGTTCAAGTGATGCTTGTGCCTCAGCATCCTGAGTAGCTGGGACCAAAAATGGCAAGGCTCTGCCTCTACAGAAAAAAAATTTATTTCTTTATCTTTTTTTTTTTTTTTTGATATGAGGTCTCACTATGTTGCCCAGGCTGATTTTGAACTCCTTGACTCAAGTGATCCTCCAGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCATGCCTGACCTCTACAAAAAGTTTTTTTTTTTAAATTAGCGAGGTGCAGTGGCACAAACCTGTAGTCCCAGCTACTCCAGAGGCTGAGGAGGATTGCTTGAGCCCAGGAATTCAATCATGCCACTGCATTCCAGCCTGGGCGGCAAAGCAAGACTTCGTCTCTTTGGGGGGAAAAAAAAAAAAAAAAAAAAAATATATATATATATATATGGCTATGACTGTTTCTCTAGAGCACTGATTTAGCCCTATCCTATTGATTCTGATATATTATTCTTTAGATGTTCTTTAATTTTGGTTTTAATTTGTTCTTTGACCTAAGGATTGCCTTAGAAAGAGTTCTTATAGTTCCAAGTTTTGTTTGTTGCTTTAAAGTTTTACTTTTATTACTTAATTTGTCCAGAGAATATGATTTGAACTATTTCCCTTTTTTTTTTGGATTACATTGAGATTTTCCTTGGGAGCCATTATATGTGATTTTCTTTTTCTTTTCATGTTCTCTAGGCACTTGAAAAAAAAAGTCTATAGCATTCTGTTTCTGAGTGAAAGCCATGGTTCTCACAATGATCTGCAAGCCCCTTTGTGAGCTTGCCCACCATTACCTCACTAATCTCGTCTTCTGCTATGCACTGTCTCATTTACTACCCTCCAGCCACATGTCACTATGCTCCAGCTACATGTTTTGTCCCTGATCAGGCCATTACACTGCTTTGCCTAGAGCAGTCTTTGCTAGGTATTCATATGGCTTCTCTCTCCCTGCCTTGTGATCTTCACTCACCTGTCACCACAATGAAGCATTTCTTCTTAGCACTTTTCAATATCTAAAATACATTTTTACTAATACCCTATCACCACCACCTTCCCAGGATATAAACAAAGGTTGAGTTTTTTTCTCTTTATTCACTGCTTTGTTATTTTTCTGATAATTTAGAATGCTTGTAGTCTCAGTTCTTCAGTTGGTTACCTTTATAACTTAAGTTCCTTGAGTTACCACCTGTAGACAGTATCTATTGGTTATGAAGAAAAACATATGTTTTTTTCTGTCTTCCATTTTTCTCTTCTACCATGGGACTCAGATTAGATATATTAGTATATTTGTTAAAAAGAATAATACTACTACTATAGGCCGGGTGCAGTGGCTCACGCCTATAATCCCAGCACTTTGGGAGGCCGAGGTGGACGGATCACACTGTCAGGAGTTGGAGACCAGCCTGGCCAACATGATGAAACCCTGTCTGTACTAAAAATACAAAAATTAGCTGGGTGTGGTGGTGGGCGCCTGTAATCCCAACTACTCGGGAGGCTGAGGCTGGAGAATCACTGGAACCCAGAAGGTGGAGGTTGCAGTGAGCTGAGATCTCACCACTGCACTCCAGCCTGGGCAACAGAGCAAGACTCTGTCTCGGAAAAATAGTTGTTTTTATTACTTTAAATAAATAGATTGTGCTGAACCCTTTATTATTATTTAATCTGCTTTGAACAACATCCATATCCCTTCCAATATCAAAAAGAGGAAATTGGCATACCTATCACATTGCCTCCTCCCAGTACTTGTTGTTACAGTATCATTGTTTCTACAGGGTCAAGATTTCTTTTTTTTTTTTTTTTTGAGACAGAGTCTAGCTCTGTCACCCAGACTGGAGTGCAGTGGCTCAATCTTGGCTCACTGCAACCTCCATCTCCCGGATTCAAGCGATTTTCCTGCCTCATCCTCCTGAGTAGCTGGCATTACAGTCATGCGCCACCACGCCCAGTTAAGTTTTGTATTTTTTAGTAGAGATGGGGTTTTGCCATGTTGGCCAGGCTGGTCTTGAACTCCTGACCTCAGGTGATCCGCCCACCTTGGCCTCTCAAAGTGGTGGGATTACAGGCATGAGCCACCACTCCTGGCCCATTGTCAAGATTTCTAGTATTTACATTCAGTTCTATAACTTAAATCCCCCACTTATTTAGATCTAGTTTTATATTTAGGTGGATTCAGTGTTCTCCACCATCCTTTATTATCGTTGCATTTCCTGAGGACCTTGTTCCACAATGTAAACCAACATGGTTTCCTTGATTAAGTCTTACTATCAAAAAATAGAAGAAAAAGGCCGGGCATGGTGGCTCACACCTGTAATCCTAGCACTTTGGGAGGTCGAGGCAGGCAGATCATGAGGTCAGGAGTTCAAGATCAGCCTGGCCAATATGGTGAAACCCCGTCTCTACTAAAAATAGAAAAATTAGCTGGGCGTGGTGATGTGCATCTATAGTGCCAGCTACTTGGGAGGCTGAGGCAGAAGAATCGCTTGAACCCGGGAGGTGGAGGTTGCAGTGAGCTGAGATTGCGCCACTGCACTCCAGTGTGGGCGAGAGAGCGAGACACTGTCTCAAAAAAAAAAAAAAAAAAAAAAAAGAAGAAGAAGAAAAATGGTCAGCTGAACTGAACAGTGTCCCTTGTCATATAGAGGATTATATTTTGGTACAAGTTCCTAGTCCCATTGTAGATTGGAGACAGTTTGCAGATCAGCAGTGGTCAAGGAACACATTTTGAGAAGCACAGTTTTACCCAGAACTTGAATAAATGTCCTTGATTTTTTTAAGTCTAAAATCCTCCCAGATAATGCAAGGGCTTAGAACACTTTACCTCCAATACCTTTTTCTGTTAATATGTATACTATTTGTTGTCATGTATATTAAGTTCTGTATTCTAGACTCCATAAGGCATTATTATTGTTTTATACAGTGAAAATTGAGATTTACCCACATATTTACTTTTTTGGGTTGGTCTTCATTCTATCCTACATACCTAAGCTCCCATCTTAGATGATATTTCTTCTACCTGAAGAAATCCCTTTAGTATATTTCAGTGTAGATCTGCAGGTAACATGATCTTTATTTTTAAGATTATTTTGTTTTATATTGTTTGAAAGTATTTTTATTTCATCTTTAATTTTGAAGGATATTTTCTCGGAATATAGAATTCTTTTGGATGTTTTTGTCAGTTGGCTAAATAAAAAAATAGAATCCTTCCAGCACTTTGAAGTTGTAATATTAATTTGATATATTCATATCATGTGACTGTATCTTAACCCTTAAGATTTATCACTCAGTGAAAATATTTTTTAG
Seq C2 exon
CAGGCTTATGATCAGAAGAACATTAGGCGAAGAGTTTATGATGCTTTAAATGTGCTAATGGCAATGAACATAATTTCAAAGGAAAAAAAAGAAATCAAGTGGATTGGCCTGCCTACCAATTCTGCTCAGGAATGTCAGAATCTGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000114126-TFDP2:NM_006286:5
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.342 A=NA C2=0.058
Domain overlap (PFAM):
C1:
PF0231915=E2F_TDP=PU(55.4=83.6)
A:
NA
C2:
PF0231915=E2F_TDP=PD(42.2=71.4),PF087815=DP=PU(4.2=12.2)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)