HsaINT0167077 @ hg19
Intron Retention
Gene
ENSG00000156299 | TIAM1
Description
T-cell lymphoma invasion and metastasis 1 [Source:HGNC Symbol;Acc:11805]
Coordinates
chr21:32490736-32497012:-
Coord C1 exon
chr21:32496840-32497012
Coord A exon
chr21:32493156-32496839
Coord C2 exon
chr21:32490736-32493155
Length
3684 bp
Sequences
Splice sites
5' ss Seq
CAGGTACTG
5' ss Score
9.04
3' ss Seq
ATTTTTGTGTGTGTGTGCAGTGT
3' ss Score
8.23
Exon sequences
Seq C1 exon
CTCCCCAGAGAGCCGAAAGGATTTCCTAAAGGCTGTGCATTCAATCCTGCGTGATAAGCACAGAAGACAGCTCCTCAAAACCGAGAGCCTTCCCTCATCCCAGCAATATGTCCCTTTTGGAGGCAAAAGATTGTGTGCACTGAAGGGGGCCAGGCCGGCCATGAGCAGGGCAG
Seq A exon
GTACTGTGGGGATTCGGACGTTCAAGATTCCCGTCACCCCCACTCCGCAGTAGAACTCCAGTGAGCTTGACCTCCTTGTTGAGTGGGGGTGAGGTGTGGCCTGGTGGGGGCTGATGTAGGAGGACGGTTTTTCCCTGGTGTGAGGTTCCTTGCCCTTGCCTCCTTCCCAGTGGCTCCTGGGGATCCGCCCTGTATCTACATTCCTCTTGTCCTCCCTCAAGCCTTCCCTTTGCCTCCCTTCTCCTTTTGGCTGGTGAGCTCCTCCCTCATTTGCCAAGTCGGGTTGCAGACACATCCTCTTTCTGGAGAGGCTGTCTCAGCCTGCTTGCAGAATGAGAGTCGCTGCTTTGCATGACAGCCAGCTTTGTCTAGCAGAAAGCCGTGTGTCACATTTCAGCAAGGTCACAGCCCTCTGTTCTGAGAACATGGTGGCTTCACGGCCTGGCAGCACAGCAATGCCTGCTCTCAGTAGTAAGGATTCTAGGTTTGGTAGCCCACATGGCACTTCCAGTTTTTATCCTGACCTTGTGCCTGCAACTTTATTTTTAGTCTCCATGTTAATTTGGGGAAGCCTCGAGCTATTCTTGGAAACAAGAATCTAGAGTTTAAATGGTCCCAGCATAAATATTCTTGTAGGACTTAATCCATTACAGTGGAGCAATAGAGAAATAAAATAAATACTGCCACCTGTCAATGGTAGCAAAATGTATCTAGGAAGAAGGCTGTTTTAATACTTAGGGACTTAATGACATCAAGATACTAACATTTTTATCAAACCTTTCTTAAGAGGCAGCCCAGAATTTTGCAGGGAGGATTTCATTAAAAGAAGGCCCCCTTTGCACTTGCCAGAAAAGTTTCTGGCCTTTGTACCCATTACCATCCTACCTATTGAAGAGGGATGGACAGAAGTGTGAATGCTTGAAGGTTTTCATAGACAAAACCTACCTGGCTTGACATGGGATATTACATTCTTCAAGCACCTTAAATTTAATTTAGGGGACTAGTTACTGTAAACCTCTTCTCCAATCAATTGATAAATGTTTGTTGAAAACTTAGTGCAGTGAACACCCAGCACTTTGCTGAGTTTTCTGATGTATCCTAAGAGTCTTTCATACGTCCATATGCGCAGTTTCGCATGGGGTCGCCATGGAAGAATAGTTTATTGGTCCTTTATAACTCACTTTAGAGATTTTTATCTTGGATTTGTCTTATCTGCCCCTCTTGTTTGCTAGGGAAATGTTTAAAAAGGTTTGGGAATATGTGTCTCAACCTCAGGGAACTCAACCTGTTTCAGTTGTTAATCAATGAACCTAAATTCAGAGCTGCATTTACTTTGAAACTAAGCATGGTTAGTCTGTCACTCAGAAGTTTTCCTGCTGAGATCCATTTGGAAAGAAAACAAAACCAGCCCACAATTTAACACCATCGTCCGTCATGATTACCAAGAGAAAGCCTTGATGTCATAGCCTGTTGGATTTAGCTGATTGAAAGATCTTTCTGCCTGATGGCTCATTTTTGGCTGAAGAAAGTCTGTATCACTTTGTTTGGAGGCATCTCACTATCCTCAGAATCTTCATGTCAGAGGATTTTAAAATGGTGCCTGAGTAGATCAGCACAGCATAGCTGGTCAGTCTTAACAGTGACCACTGGAAATAGTCAAAGATTGCATCCCTGAAAGACTGGGAAGAACCCAATAATGGTAGCCGGGTTCTTAAGCATACTAGGAACAGATACTCATGCTTCATTTTGCTTTGTCTTGAATACTCAGGTAGTTTATTTCTCCCTCTGTTCTGTTTGGCTAGGATAGTAAAGCCAAATACTCTGCTTCCATATTCAGCCTAAAGTACTATACGTTTGCCAATAACCCAATTAAAAATTTTTTTCTTTGTTCTATCTATTTTCTTATGAAAATGTTTAAACTTATAGAAGAGCTGAAAGAATTCATACCTACCATCTATATTCTATAATGTTTTTCTATATTCTCATTATCACTCATCTGTTAGAATCCATCTGTCATCCATCACCTCATCTTATTTTTGACATATTTCAAAGATGTAGACATTAACACACTTTACTCCTAGATACTTCAGCATGCAAATCATTAACAAATATTTCCAGTAGCTTTGAGTTGGGGTAGTTCTAATGTGGTGATTGGAGAGAGGGATGCTGTATTTTGCTGGTGCTGAGATAAAAGTGAACAAGAATTTTTGTCTCTTCTCAATAGAAGTCAGAGTTTGTTTGTTTTTTTTCCTATTTTCTATTCCCTTTTTCCATTTTGCCTGGAAATGGCTTTTATTCCCATCCTCAACCAACAGTAGTGTCCATTTGTTCCACAGTTTTAGATGGCGGAACACTCAGGAATAGTGATGGACACGCAGGGGTCTGAAGCAGAGGATGGCTGCCATGAGAGCCAATTCAGCCCCTCGTTGACCACTCTAACCCTGTGCCTGCTGGGTTCGAAGTCAAGGCTGCATTTGGCAGTAATTGAGACACGAGGCATCTTCTAGCAGCACTGAAGCAATTGGATGGTTCTGGGGCTTAGGTTTCAGGAAAGCAGCTCCCAGTTGGCGTTGAGACTCTTCCCCTCCACTGGAAAGCCCGTGTTGCATTTCACCTTTTCGTGTCTAATGCAACAACCGCTTCACTCTCGAGGGAGAAGCAGAAGCCTTCCCTGTGAGCAGTCTCGTGTATGTGTGTGGTGGGATTGTTGGCTTGATCGGATGGTGTCTTTTGTTTGCTTGTTTTTAATTCTGGCTTCCTAGAGGGCAGTAGGTGAAAGAATGAATTTTTCTTAACTGGTAGTCACTTTATACAGCACTTTGTTGATCAAACTGCTTGGATGTCATCGGTTTTTTATTTCTCATTCCAATGAGGCACTGATATGTTAATTGCTTTGGAGAAGAATGAGTGATACACAGACTGTAATTGGGGGAGACTAAGGCACACATTTGCTTAGCTTCCTAGCTCATGTGGGACTTTGTCAGAAAGAAGACAGGGAAATAACTGAAGATCCCATGTCTTTGAGAGCCACTCTTTTTCATAGGCTCTCTAAGAGTGACGTGGTGCCCTTAATCTAACTGCAGATCCCAAGAAATGTTATGTTCCAGTTCCCAGAAAACAAGTAACTTACACTGGTGCTTCTGCCTCCTTGATGCACATTCTACAAAGACAGCAAAACCATAGATGCACCCCCACCCTTACTAAAGACCTATTCCAGCTAAACAACCCTGGGACAGCCCTGGGGATCTTCATAGCACTGGGCCATGGGACATGGCCAGGATTGAGGACACTAACTCACTAACTGATCCCCAAATCAGTGGTCTGTCTACTTGAGAGCAGCTGCTGTCTGTGTTACCCATCTCTTAGGTGCACAGGCTAGAACAGTAGATTATTTCAGAGGGAGTTGAGTGCCCCTTTGCCCATAACCTACAACCTCTCCTGTGTGCCCCGGTTCCCCCTTGCCCTTGCATCAGTTGCTAGAACATCCTCTAAGTCCAGATACCTCGACAAGGTAAATGCTCCATGACAGATTGGTGATATGTAGACTTTAAGCCCCAAAAGACATCAAGGCATTCAATGCATACCGTTTTGGTTTTTATTTTCTCCTGTCCTTTGCTTTCTGGATTTTCATCTCACGTAAAGCATGTGGGGGTTTTATTTTTATATTTTTGTGTGTGTGTGCAG
Seq C2 exon
TGTCTGCCCCAAGCAAGTCTCTTGGGAGGAGGAGGCGGCGGCTGGCTCGAAACAGGTTTACCATTGATTCTGATGCCGTCTCCGCAAGCAGCCCGGAGAAAGAGTCCCAGCAGCCCCCCGGTGGTGGGGACACTGACCGATGGGTAGAGGAGCAGTTTGATCTTGCTCAGTATGAGGAGCAAGATGACATCAAGGAGACAGACATCCTCAGTGACGATGATGAGTTCTGTGAGTCCGTGAAGGGTGCCTCAGTGGACAGAGACCTGCAGGAGCGGCTTCAGGCCACCTCCATCAGTCAGCGGGAAAGAGGCCGGAAAACCCTGGATAGTCACGCGTCCCGCATGGCACAGCTCAAGAAGCAAGCTGCCCTGTCGGGGATCAATGGAGGCCTGGAGAGCGCAAGCGAGGAAGTCATTTGGGTTAGGCGTGAAGACTTTGCCCCCTCCAGGAAACTGAACACTGAGATCTGACTGCGTCACCTGCCCCGTAGAGAATGTGTGTAGATACTTCCTGCCCTAACTCTGCCCACCCTCCTGTACCGTCGACAAGAATGTCCCCTTAGGTCGCGCTCTTGCACACACGGTTTTGGCAGCTGACTTGGTTCTGAAGCCATGTAGCCACCCAACTTTGTCATTTTCAACAACATCAGAAAGAATTGATCAGAATCCCAAATAAGCTTGAGTCCTATCTTCTGTATATTACTAAGGGCTTTTATTTATTCTCAATAAATCAGGGCCTGAACAATTAAAAGAAAAAAGATTCTATAGCACTGGAAAGCAAATCACCCCAGGAGTTAACGGATGTACAACAGATTAATTTAAGGGATAGTAGCACACACACGATCCTTCTATCTGAAATCAGTCTCCTAGCTGGGGAAACCTCTTTCACACACAAAATGAAATGTGTACAGCTTGCCGTGTTCTGACTGTACCCTTCCCTCTTCCATGTCTGAGAATCTCCGTGTATTTTAAGAATGTGTGAGGAGAGGGTGGCGATTCATGTTTCAATGAGCCTCTTTTTTTTTTTCCTTCCTGTTTTGGTCTATGGCTGGTCTTACTCTGTGTCCATGTTCGGAAGCTCTAGTTTTGCATAGAATTATAGAGATGCCAAACTCTTTGAAAAGAGATCCAAATTTATCGCTTGAGAGAAAGAAAAGAAACACTATTTTTTGTATTTTACCTGAGATACAGGGGCACAAATAGATGAGAATTTTACAGTGTTAGTGTATGTATCCCTGAGCCTAAAAAATGAGGATATAACCTTTTACAGAGAGAGTGAGGCGTGGTGGTTTTATATTTATATATGAAAGGCCAGCAAGCTCATGCGAAGGATATACTTTTCTTCCAAAAAGCGGATTTTTTTTTTTTAATGTTTGAATCTATATTTGAGATGGGAGTTTGGTTGGATTAAACATGACACCCCGGTGGGCGGTGTGTGTGTCTGTTGCACATGGCAGGGAGGGGAGCCTCCTTCTCATGGGGTTGCCATGGTGATCATTGGTTTTTCCATCAAAATTGCATCTTCATCCATAGATTACCTTCCCCTTCCCTGACAGTCCATAACCAAACCTTTAAACAGAACAACCTCTTTAAAAACTTCTCTTGTGTTTAACACTTTCTTCATGCCAACGAAACAGGGTAAACATGCTCAAAACATTAACAGTCTAAACAGATATCCAAATACTAAGAAGAAAAACAAGTTATAGCACTTTCAATTTTTTTTTTTTTTTTAAAAAAAGGTTTATAGCTTTTTCTTTTCCCATGTCACAATGTCCACTTCCTAAGAAGGGTTTAAAATACTATGAAAACTTTCTTTTTGGGGAAAATATCTATTTGGTGTTTGACACATCAGTAGGTACTTTAAAGACCTGAATTTTATAGTAGCTTTAGGAGTTATATTTTATAAAAATCAGTTATGACTTTATATTTCCAGACAATAGAGAGTTCAGTACATCATGCTCTTGTGCCTCTGCCTGCTTTTCCTGCGTTCCCACCCTGTATTCCCCCCGCCTTTCGGGTTTCCAGGGCTTCGAGCTTGATCTTTTGAAAGTTTTATTCTATTAAATTTTTGCTATATCTTCTGGTTTTCTGAAAAAGCTTTAGAATGGTTTCTATACCCTTTGTATCACTGCATTTTTCCATATCATCTCCGGTTCGATCGCGTCCAGATGGAAAACGGAAGCAGAGGCTTCTAATCGTCGCATTTACTGGCTCCAGTGCAACACATCCATCTGAAAACACTCGGAAGTCTGGTGCTTGGAGAGGGTGCCATTGTCTCTTGTACATAAGGTCATGACGTGTCTATGTCAAAAGTTCTTATATATTTCTTTTATAAGCTGAAAGAAGGTCTATTTTTATGTTTTTAGGTCTATGAATGGAACGTTGTAAATGCTTGTCAAACAATAAAAATAACGAAAAGTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000156299-TIAM1:NM_003253:28
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.133 A=NA C2=0.551
Domain overlap (PFAM):
C1:
PF0016924=PH=PD(12.8=28.8)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)