HsaINT0169666 @ hg19
Intron Retention
Gene
ENSG00000137747 | TMPRSS13
Description
transmembrane protease, serine 13 [Source:HGNC Symbol;Acc:29808]
Coordinates
chr11:117771360-117774522:-
Coord C1 exon
chr11:117774370-117774522
Coord A exon
chr11:117772981-117774369
Coord C2 exon
chr11:117771360-117772980
Length
1389 bp
Sequences
Splice sites
5' ss Seq
GAGGTAAGA
5' ss Score
10.06
3' ss Seq
TCTCCCATTCTCTTCCTCAGAGC
3' ss Score
10.21
Exon sequences
Seq C1 exon
GGAGACAGCGGGGGGCCTCTTGTCTGTGAGCAGAACAACCGCTGGTACCTGGCAGGTGTCACCAGCTGGGGCACAGGCTGTGGCCAGAGAAACAAACCTGGTGTGTACACCAAAGTGACAGAAGTTCTTCCCTGGATTTACAGCAAGATGGAG
Seq A exon
GTAAGATCCCTGCAGCAGGACACTGCACCCAGCAGGCTGGGAACTTCCTCAGGTGGGGACCCTGGAGGAGCACCCAGGTTGTAGGCAGAGGTCCCCTCAGCGTCCCCATATTCGGGGGGTGTTCTGGACAGGGTCAAATGTGATGCCTGGGGTCAATCCCAGCTGTCTGTGTTTCTTTCCCTGCTTTTCTTCCCTCAGAACAGAGCTCAGCGGGTTGAAAAAGGGTGGACCTACAGGCCAGGCAGGCAGTTGCTGGGCAGATGTTCTCCCAGAAGTATTTTTTTGTGTAAGGTTGCAATGGACTTTGAAAACGTTTCAGTTTCTGCAGAGGATTTTGTGATAGTTTTTGTTATCAAGCATTTATGCATGGGAATCCGCTCTTCATGGCCTTTCCCAGCTCTGTTTGTTTTAGTCTTTTTGATTTTCTTTTTGTTGTTGTTGTTGTCTTTTTTTAAAAACACAAGTGACTCCATTTTAACTCTGACAACTTTCACAGCTGTCACCAGAATGCTCCCTGAGAACTACCATTCTTTCCCTTTCCCACTTAAAATATTTCATCAGAACCTCACTACTATCATAAAAGAGTATAAAGTAATAAAATAATAAAAAGTTATTTTATGTTTTTTGACTTGCTTTAACCTATATCCAACCTCAGAAGTCATTGCTCAGGTCAAACTGAACCACAGACCCTTCAGTGTGTGCCTTACCTTGCCCTTGGCCTTTGGAATACTTGATCCACCCTAGAGAGTCCCCTCTCCCACTTCCACCCTCTCATCTTCCATTTTTCTTACTGAAGAACTCTGACTAATCTATCAAAATCAGCCATTTACAATGCCTGGAATATCCTCGGTATTTACTATTTATTGTTATAAATTAAGGATGAATGAATAAACAAATAAATGAAAAGAATAAAAGGTGGGCCTCACCTCGGTGCCAGCCCCAGTGCCACTCTCCTCTCCCAGGGATGACCGAGATGTGAGTTCACACAGGCCGCTGGCAGTGGAGTGATGGGAGGCCTCCCTCCACGGCAGGAATTTCGGTGTCAGGAAACAGGGATCTGCCTGCAACTCTGCTGACCTAGTTGAGACCCTGCCTTCTCTGGGCCTTCAGCCTTTAGCTGTAAAGCAGGGGGTGCTCTGCCAGCCCTCCCCTTCTCTGCCTGGGGAACAGGGGAGGGCTCAGATAGGGGGAGCAGAAAAGGCTCCAGAAATCTAGTGCAGAGAGGCCCTCCAATCCTGCATCCATCCTTTCCCTTTGCTCTCCCTCCTTGGAGAGGCAGTGCTAGGTGACAGCGAGGCTAAATTATAGGTTCTGAACCCCAACCTTGGGCTTCTGTGCTCCTCGCCCACCTGGCCCACCCTCACCCTCTTCTCCCATTCTCTTCCTCAG
Seq C2 exon
AGCGAGGTGCGATTCAGAAAATCCTAACCAGCTGGCCTGCTGCTCTGCACAGCACCGGCTGCTGTGAAGACTCTGGCCATGGTGACTGGCCATGTGTGGCATCATCTGGGCTAATGGCCACCGGGCACCATCGGACTCCCACCTCCACTGTCTGCTGCCTCTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGCATATGTGTGCATTGCCACTCTCCCAAGTTTTTCAGAAACCAGCAGAGCTGTCAACTCTTCTCAAAATCCCAGGCTGGAAATTACCTGGAGACAAGAGTTGAGTACCGTGGATGTTCCTACAGGAGTGTCCATAGATGGATGGAGGAGGTGGAGCCCAGAGCCCAAGGAAGAGCTGGGAATTCTTGCTTCTCTGACCCTCACTTACAGACTAGCCCAGTGTGGGCAGATGCCAGCGGCCCAGGTGGCGCCATTGCTGTCCTGGGATGGATCGTGGGTTTTGGTGGATGCAGCTTCCCAGGGCCTGGACCGTCTTCGGTGAAAAGCTGCTCCCGTTGGCTTTATGAGCATCAAGTCCTCACCCAGACCCCCTGCTGGTGCCGTGGATGTCACCAGTCGGACTGTGCTGTGGCTAACCAGGCTGACAACTGAGATGAGGATTCACTGTACTCATTTGGTCACAAGCTGCTGGGGCGGGTTTTATTTTATTTTATTTTTATATTTAAGAAATGAAAATACGGGTATTTTTAAAGATTCTCCAAAAAGTCCAGAAGCCTTGACAGCTGGCATCAATCAGCCCAAGACCCCCAGGGGATTCATGGGAAATGTCGTATTTTAGAGTCCTACAGAATATTTCTGGCCTCAAGGAACTGGATGAAGAGACTGGACAAAGTCCCCAGGATGGGCATCCCCCAAGTCACTACAGCATCTGGAGCCCCTAGGAGATACTCAGGGAAGCAAATCCTTGTTTGGGCTGGCAAGCAAATCCGACACGACGAGGTCCACAAACTGTTTCTGCATCCCAGGGCTCTGACGAAGGCGTTAAGAAACAGATGCTGTTCCCGCGTAGGCTCCCAGGGGCCCCAGGGAGGTCCAGGTGGACTGCCTCTCTCATTCCCAGTAGCTGTCCTGGGACTTTGGGATTTCTTCTCAGCTTTCTCCACCTTTCAGTTTCTCAGTTGTTTCAGAAACATAGCAATGACATAAAAACTGCTATGGAGAGAAAGCTAACATGGTCCCATGCCTTCCAGGCAGCCCTGCTGAAGGATCTAAGTTGGCCCTGTTCCTGCAAATCATCAACGTGCCTGGACTCGCCAGCTAAAAGCCTGGGCCTTCCCCAGCCTTTTTTCTGGGGCACCTATTCCTCTGCCAGTCCTGCTCCCCTCACCTTCCTTGGGCCCGTCAGAGTCTTTTGTGGTGCTGTGCTTCTCAGAGGCAGGATCCAAGCAGATCAGCCCAGCCTAGCCCAGCTCAGGCAGGCCATGGCCGCTCAAGGGAAAGACTGCCCCAGAAGAGCAAGCTGGAGAGGCTGGGCAGGGGCTGATGGGGCTGGGTACACTGGGGAATGTTAGCAAGACTGGGAAGGAGGCCACATTCCTGTCTGCAGCAGCCGCCAGCGATGGTCTTCAGCAATAAAAGTTGTGTGACCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000137747-TMPRSS13:NM_001077263:12
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.035 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=PD(19.7=88.2)
A:
NA
C2:
NO
Other Inclusion Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAGAACAACCGCTGGTACCTG
R:
AACTTGGGAGAGTGGCAATGC
Band lengths:
346-1735
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)