HsaINT0175317 @ hg19
Intron Retention
Gene
ENSG00000137285 | TUBB2B
Description
tubulin, beta 2B class IIb [Source:HGNC Symbol;Acc:30829]
Coordinates
chr6:3226393-3226903:-
Coord C1 exon
chr6:3226795-3226903
Coord A exon
chr6:3226504-3226794
Coord C2 exon
chr6:3226393-3226503
Length
291 bp
Sequences
Splice sites
5' ss Seq
CTGGTAATC
5' ss Score
3.45
3' ss Seq
GTCACTGTTGTTCCTTGCAGGTA
3' ss Score
11.49
Exon sequences
Seq C1 exon
TTTTGGGAGGTCATCAGTGATGAGCATGGGATTGACCCCACTGGCAGTTACCATGGAGACAGTGATTTGCAGCTGGAGAGAATCAATGTTTACTACAATGAAGCCACTG
Seq A exon
GTAATCACCCTTGCCCCACCCCCACTCCCTTCAGTTTTTCCACCTTCTCCCCTTTCCCTTGCGTGGGACCCCAGGGGTGTGGCCCTGGGAGAGGGTGGACTATTCAGTTTAGGATCCCCGCTCTTTCCCTGCAGTATTTCATTGGGCTTCCTTATGCCAACAGAGCCCTTTGAGAACCTGATGGTGGGTCTCCCTTTGTTTGGGGCAACATCTGCATGATGGCAGCAGGCGCCAAGCCCTTCTCTGCAGAGGTCCTTGCCTGAGGGTCTAAGTCACTGTTGTTCCTTGCAG
Seq C2 exon
GTAACAAATATGTTCCTCGGGCCATCCTCGTGGATCTGGAGCCAGGCACGATGGATTCGGTTAGGTCTGGACCATTCGGCCAGATCTTCAGACCAGACAATTTCGTGTTTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000137285-TUBB2B:NM_178012:2
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.135 A=NA C2=0.026
Domain overlap (PFAM):
C1:
PF0009120=Tubulin=FE(16.2=100)
A:
NA
C2:
PF0009120=Tubulin=FE(16.7=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTTTGGGAGGTCATCAGTGATGA
R:
CAAACACGAAATTGTCTGGTCTGA
Band lengths:
220-511
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)