HsaINT0175317 @ hg38
Intron Retention
Gene
ENSG00000137285 | TUBB2B
Description
tubulin beta 2B class IIb [Source:HGNC Symbol;Acc:HGNC:30829]
Coordinates
chr6:3226159-3226669:-
Coord C1 exon
chr6:3226561-3226669
Coord A exon
chr6:3226270-3226560
Coord C2 exon
chr6:3226159-3226269
Length
291 bp
Sequences
Splice sites
5' ss Seq
CTGGTAATC
5' ss Score
3.45
3' ss Seq
GTCACTGTTGTTCCTTGCAGGTA
3' ss Score
11.49
Exon sequences
Seq C1 exon
TTTTGGGAGGTCATCAGTGATGAGCATGGGATTGACCCCACTGGCAGTTACCATGGAGACAGTGATTTGCAGCTGGAGAGAATCAATGTTTACTACAATGAAGCCACTG
Seq A exon
GTAATCACCCTTGCCCCACCCCCACTCCCTTCAGTTTTTCCACCTTCTCCCCTTTCCCTTGCGTGGGACCCCAGGGGTGTGGCCCTGGGAGAGGGTGGACTATTCAGTTTAGGATCCCCGCTCTTTCCCTGCAGTATTTCATTGGGCTTCCTTATGCCAACAGAGCCCTTTGAGAACCTGATGGTGGGTCTCCCTTTGTTTGGGGCAACATCTGCATGATGGCAGCAGGCGCCAAGCCCTTCTCTGCAGAGGTCCTTGCCTGAGGGTCTAAGTCACTGTTGTTCCTTGCAG
Seq C2 exon
GTAACAAATATGTTCCTCGGGCCATCCTCGTGGATCTGGAGCCAGGCACGATGGATTCGGTTAGGTCTGGACCATTCGGCCAGATCTTCAGACCAGACAATTTCGTGTTTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000137285:ENST00000259818:2
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.135 A=NA C2=0.026
Domain overlap (PFAM):
C1:
PF0009120=Tubulin=FE(16.2=100)
A:
NA
C2:
PF0009120=Tubulin=FE(16.7=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTTTGGGAGGTCATCAGTGATGA
R:
CAAACACGAAATTGTCTGGTCTGA
Band lengths:
220-511
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains