HsaINT0176817 @ hg19
Intron Retention
Gene
ENSG00000144357 | UBR3
Description
ubiquitin protein ligase E3 component n-recognin 3 (putative) [Source:HGNC Symbol;Acc:30467]
Coordinates
chr2:170804052-170806575:+
Coord C1 exon
chr2:170804052-170804225
Coord A exon
chr2:170804226-170806114
Coord C2 exon
chr2:170806115-170806575
Length
1889 bp
Sequences
Splice sites
5' ss Seq
CAAGTAAGT
5' ss Score
10.08
3' ss Seq
TTTCTCTTTGTTAATGGTAGAAT
3' ss Score
6.74
Exon sequences
Seq C1 exon
GCATCAGTGGGTGGACCAGAACGTTGTCATGACAGTTGGTTTCCTGGCAGTAACTTAGTGTCAAACATGCGACACTTTATAAACTATGTTAGAGTAAGAGTTCCAGAGACTGCTCCTGAAGTAAAGAGAGACTCACCTGCAAGTACTAGCTCTGATAACTTGGGTTCTTTACAA
Seq A exon
GTAAGTGTAAATGTAAGAAAGAAAATAAGAAAAAGCTTTATGTTATGTATGTTATGTTGGGATATACTGTTCCTATAATATCCAAAAGAAAAAAAAATGTGGTTGTAGATAACTTTAAATTGTCTTTTATTTCCTCTGATATATCTATGTAACTTCTACCTTACCAGTCTTTTTCCCTTAATCTGCCAGAGTTCACGACGGCCTAAAGTTCTTCAAAGAGAGGTAGATGTGTATGATATTTTCATTAACTAGCAACATGGCTTTAACTGGAAATGGGGAAAAACCGCTTTGAAGTATTTGTGTGTGTATGGGTGTTTAATTAATATGGTTAAATTTAAAAGAAGGTTTCTTGGATTTATGTGTGTTTTTTTTTTTTGACAAAGTGATTTAAGCTTAATATTAAAGAAAATTTATATTATTGAGCTTAAAAATAATACTGAGTATAATAGTGTATTTTTCTTATTAGTGTTCGAAGTATTTTGGACCAATTATAGGTAGCATATTTGAGTCTCTTTACATTCATCATTGCCACTGTATTACTAACATCTTAAAAATGACTTGGATATTTTCTAAATTAAAATAAATTTAATTGCTAGCAGCATGCTCATTTGCAAATAACTTTTTTTTTGCTTCTATGGCAATTAACTTTGATAAAATAAGCCTATAAAGTCTTAAATTCTGTATATTATGGCTTTGGACTCATTTTGAAAATCAGCGCTCTCATTGCATGTAAGTTAACTTTTAAAAAGCAGTAATGAAAAATCTTGAAATGACATTGTAAGTAAGTAAACTTAAGCAGTTTTAGTCTCCACAACCTAGATTTTCGTGAGTAGAGAACATTGAATCAGACATTTCTTCTAGTAGAGTCTATTTGTAGGAGCTTTCTTGGTCTTTGACAACGTGTTTTCACTGTAAGCAAAAACTGGAAACTCTGTAAGAGGCTTTTGCCTCTAATGCTGGTAGAGAGTACTTTAAAAAACAGCTTGGATGTTAAAAAATAGTGTATACTGTCATTTAACTCACAAAAGCTCAACTGATATTACAGCATCCTTTCTATGCTCGCTTTTAAAAAATAAATTCATTAAACTGACTCATATCTTAATTAAAAGATGTTTTCTGAGAGCCCTGGTGCAGTTTGATTGCTTTAGCAAAAAAGCTTTTTAGGAGATGAATTATTGAGGAAAATACTTAGTTTAAAAAAAAAACTGTTCAAAAAACAAATCATAGTCCTTGACCCACAAACCAAAAACAAATCAAAAACAAATCACAAATCACAGTTTTAATTTCATATTAAAATTTAATAAAACAAATTAAATTTCATATTAAAATATGAAAGTTTGATTTTTCATCCTTATATTTCAATTTAGTAACTTTAAGCATTTATGTTAGAATTTTCAAACTTTAAAGTTCCTTAAAAGTGAAATTAATTACTAGTTCAGATTTATTAGCTTAGAAAATTTTTTTAAAAACTAATTTATAATTTTCTTAACTGGAAACTTTAGCAGTCTTCCAGAAGTTAGTAAGGAGTATCCTATTCTTCATGAATGTTGACCAGAACAGCTTTTCCTCTTTTAAAGTAATGAATAATTTAGTTTATGATTCTCTTTAATATGGCTGTAGATACTACTTAAGCTTTGTCTGTTTTCAGAAGGTTGAAAAGGAGATGTTACTGCTGATGATCTCCTCCTTATTACTGTTTCTAGATTGAGTGGGATTAAATATATTTGAGAGAGAGGTCAAGGGAGAAATTTATTTAAAGAGCAAATCTATTGAATAAATCTTTGTATGAAACTGAGCATTCCCTTTAGAAAATATAGTACTAATATGTTTTTAAAATGATGCTAAATAACTTCTCTTGATTTTTCTTTGTTTCTCTTTGTTAATGGTAG
Seq C2 exon
AATTCTGGTACAGCTCAAGTTTTCAGTTTAGTAGCAGAACGTAGAAAGAAATTTCAGGAAATCATCAATCGCAGTAGCAGTGAAGCAAATCAGGTGGTTCGTCCCAAAACTTCAAGTAAATGGTCTGCTCCTGGTTCAGCTCCACAGTTAACTACAGCCATTTTGGAAATTAAAGAAAGCATATTGTCTTTGCTAATTAAACTTCACCACAAACTCTCAGGAAAACAAAACTCCTACTATCCTCCTTGGCTTGATGACATAGAAATTTTAATCCAACCAGAAATTCCTAAATACAGTCATGGAGATGGTATAACTGCCGTGGAAAGAATTTTACTAAAAGCTGCATCGCAAAGTAGAATGAACAAACGCATCATTGAAGAGATATGTAGAAAAGTGACCCCTCCTGTACCACCTAAAAAAGTCACTGCAGCAGAGAAGAAAACATTGGACAAAGAAGAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000144357-UBR3:NM_172070:22
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.439 A=NA C2=0.221
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAGAGTTCCAGAGACTGCTCCT
R:
TCTATGTCATCAAGCCAAGGAGGA
Band lengths:
342-2231
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)