HsaINT0176835 @ hg19
Intron Retention
Gene
ENSG00000144357 | UBR3
Description
ubiquitin protein ligase E3 component n-recognin 3 (putative) [Source:HGNC Symbol;Acc:30467]
Coordinates
chr2:170734004-170735084:+
Coord C1 exon
chr2:170734004-170734147
Coord A exon
chr2:170734148-170735034
Coord C2 exon
chr2:170735035-170735084
Length
887 bp
Sequences
Splice sites
5' ss Seq
AAGGTTTGT
5' ss Score
7.81
3' ss Seq
ATTTTTCTTCTCCTCCAAAGGTT
3' ss Score
9.79
Exon sequences
Seq C1 exon
GTCTTGGAGAAAATGCTTGTGTAAAGAAAAGTCATGAAAAGTACCTTATAGCTTTAAAGAGCTCTGGACTTACATATCCTGAGGATAAGCTTGTATATGGTGTGCAGGAGCCATCTGCTGGTACTAGTTCTCTGGCTGTTCAAG
Seq A exon
GTTTGTCTAAATATTTAATTTGAACAGTTGTAACTTTTCTGTATTAAAACCAAAAAAACCTCTCAAACTTTACTCATTATTGAAAAAAATTATTTTGAACTAAAACAGTATTATTCTTTTTAAGAAAAGTAATAAAAGTAGTAAAAATTTAGAGGCAAAAAAGAATAGATTGACCAAAGAAGAGAATGCATTTTTCTTAAATGGAATTTGATTAGCTTATTAAGGTTCTGGTTCTAACTCATGAAAAATGTACAGTTGCTATTCAAGAGTAGCCCAAAACTTTACTGCCTCAATATTTTAGTAAACTATGGTTTAAAACTAAAAAGAGATCCTTCTGAAACACCATTTGTAATAACTGTATTAAATCTGAGTTTTCACTGGAGAATTCCTATTGAAGTATCAACCTATTAGGTCCAAACTTATTTGAGATAAATGTTGGAGGCTGGGCACGGAGGCTTATGCCTATAAATCCCAGCAGTTTGGGAGGCCGAGGTGGGTGGATCACCTGAGGTCGGGAGTTTTGAGGCCAAAATGGCCAACATGGTGAAACCTCGTCTTTACTAAAATACAAAAATTAGCTGGGCGTGCTGGCAGGCGCCTGTAAGCCCAGCTACTTGGGAAGCTGAGGCAGGAGAATTGCTTGAATCTGAGAAGTGGAGGTTGCAGTGAGGTGAGATTGCGCCACTGCACTCCAGCCTGAGCAACAGAGCGAGAATCCCGTCTCAAAAAAAAAAAAAAAAGTTGGACTTTGCCAAGATAACTGTTAGAATGAGGTGTCCTAACGTAACAAAACTTAGCTTTTTGATATTTGTATTTCTCAGAATAATTTGAAAATAAAGCAATATGTAGCAACTATGAAGGACAACTATTTTTCTTCTCCTCCAAAG
Seq C2 exon
GTTTCATAGGCGCAACAGGAACTTTGGGACAAGTGGATTCTTCAGATGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000144357-UBR3:NM_172070:4
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.294
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTCTTGGAGAAAATGCTTGTGT
R:
TCTGAAGAATCCACTTGTCCCA
Band lengths:
190-1077
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)