HsaINT0177858 @ hg19
Intron Retention
Gene
ENSG00000113763 | UNC5A
Description
unc-5 homolog A (C. elegans) [Source:HGNC Symbol;Acc:12567]
Coordinates
chr5:176301265-176304280:+
Coord C1 exon
chr5:176301265-176301567
Coord A exon
chr5:176301568-176304192
Coord C2 exon
chr5:176304193-176304280
Length
2625 bp
Sequences
Splice sites
5' ss Seq
CAGGTAGGA
5' ss Score
9.79
3' ss Seq
CCCTCTTCCTGCCGTTCCAGGAA
3' ss Score
11.28
Exon sequences
Seq C1 exon
ACAACCCCCATCTGCTCACCATCCAGCCGGACCTCAGCACCACCACCACCACCTACCAGGGCAGTCTCTGTCCCCGGCAGGATGGGCCCAGCCCCAAGTTCCAGCTCACCAATGGGCACCTGCTCAGCCCCCTGGGTGGCGGCCGCCACACACTGCACCACAGCTCTCCCACCTCTGAGGCCGAGGAGTTCGTCTCCCGCCTCTCCACCCAGAACTACTTCCGCTCCCTGCCCCGAGGCACCAGCAACATGACCTATGGGACCTTCAACTTCCTCGGGGGCCGGCTGATGATCCCTAATACAG
Seq A exon
GTAGGAAGGACCCCAGGGGGCTCTGAGAGCTCCACTTCCCTCCTGGAGGAGGACGGGACAGCCGGACGTTCCTCTCGTGCCCCTCGGTGTCCCGTGACAGATCAGCAAGGAAAGGGGGTGGAGTTTTGGGGAGAACCCAGTCTTGGCTGGCACCGAGGCCGTGGCCAGAGCTGTCTTCCTCTTGTTGCCTGTGGGCACAAGGTAATTGTCCATTCATTTACACAGCCAAGCAGCCTACTTGTTCCAGTCTCCATGTGGGGCCCTGGGCCCAGAGGTAGGGCAAGCCCCGGCCCCAAGGAGCTTGCAACTGAGCAGGGAGACAACCAAGGGCAAACAGATGAGCACGGGCCTGGGCAGAGGCCATCCTGGAGTCCCCACTGCATCCTGGCTTCCACCCACCCCAGCACCGAAACCCTCTGAAGAACTCTTTCCATGGCTGCCTTGCAAGAAGTGGCTGCAGCCTCTGGCATGGCTGGCCACTCCCACCCGAAATTCCCAAGTCCCTCAGCTTAGATGACCCCATGCGCTCCTGGTTTGCTTGCCCCTCTCCAGCTGCCTGTTCCATAAATGTAGGTGTGCCTCCGAGCTCCCTCCCAGTGCCCTTCTCCCCGAGCGGCCTCGCCCACTCCATGGCTTTAATCGCCGTGTCTGTGCAGATAACTCCCACTCCCCCATCCTTAGCCTGCAGTTCTCCCGGGCGACAGAACTGTACACCCAGCTGCCTCCTGGCCAGCTCCATCTGGATGTCTCACATCACCTCAGACTCCTGGTGCCTAAAACAGAACCGTCTCCCACCCTCCCCCAGAGCCTCCCCATTCCTGGCTTCCCCCAGTTCACGGATCGTCTAGTTGCTCAAGCCGGAAACTTGGGGTCACCTTGACCTGCTGCTCGTCCTCTCTTGCCCCCCGCCAGCTTCAGTCCCACGCCAGTCCCTCCTCAATAGCTCCTGCCACCTCCTGCTCTTGTCCTCCCTTGCTGCCTCTCCTGACACGGGCCACCAAACCCCTTACCTGGTTCCTTGCTGTAAAACTTCACCAAATGAAGCCAGAGTTGATCATGACCCTCTCGTGCTCGAATCCCTTCTGGGCTCCCCTCTGCCCCCTGCAAAGCCCACATGATACCACAGAGAAGACCTGTCCCCTGCAGGCCAGCTGCTTCAGCCTCTTCCCTCACACACATCGTCCCGCACACGGCAGCCACCATGGACTCAACATCCCCGACACACGGTGCTGCCCTCTGCATGCACCGACCCCCTGCCCCTCCCACCAGCTCAGCTGGGACTTCTCTTTTGGGTCCCCGCCTGACAGCTCTTGCCGTCTGTGCCTCACGTCCACACGGATGATAACGAACCCCTCATGGGGCTGTTGGGATGACGAGGTGAGACGGCATCTGTCAGCTCTTACAGAGACGCAGGCGAACAGTGGGGCCCGGCAGCCCTTGCTCTTCGCTCCCCAGGCCGGGGGGTGGCTGCCACTTCCCCCGCATCCTGTGCTGTGGTTGACTTGTCCTTCTCCCCTGCTGGGCTAAGAACTTCATGAGAGTGGGGTCTGTGGTTTTCCTTCGCCGTCCTGAGTACCCAGCATTAGGAGTTGATGAATGAGGATGTAAGTGCGTGTACCTTCCCCATGGAGAGCCTTCCTGCGAGGATGTCTGGCATTGTCACCAACACTACAGCTGGGACCGCGGGGCAGTGCAGGCCAGTGAAGGGAGCAGTGGCTGTGACTCTGCCCTCTCCGGTGAAACGGTGATACCAGCCCAGCCCTGCTCTGCGCTGCCCACGAGGGAGTGTGCATTTGCTTTTGGACTTGGTGGGGTAAAGTCATGGAATTCCTCTCCCTCCCCATGTCCTGAGCTGGGAGCCCCTCCTCATGTAAGGGCTCCCTGTCTGGGGGAGTCCCTGCTCACCACCTCTAGAGGGACTCCCTGGCCCCCGTCTTTGCCGGATCCTGTCCCACCATCTCCCTGTTGAACCACTCCCCTCTCCACTCACACGCTGATCCTGCTCCTCCAAGACGTTGGAGCAGAGGCAAGCCAGCCGACGGGAGGGCATCCAGCCCAGGAGATAGGTTATTCAAGACCCACCCCACCTGCAGGGACCATGGCATGGCAGAGAGTAGAAGGAGCAAGGGAGAGGGGAGCTGGAGCAGGACGGGAGGGCAGTGGGGGCTCAGGCAGTGGTTCCAGAACCACCAACTTTGTAGCACTGGCTGGGCTAGAGAGGCAGTGGGGGCCAGAGGCAAAGGCCCTTCAATGCCAGGCCAGGGAGCTGGACTTCATCCGGGGGCAGGGAAGGTTTTAAGCAAGGGATACCCTGGTCCCCTCCAGTGCCTTTCAGGGGACAAGGGAGGTCGGTACCGCATACCTTCTGTCCCCAAGTTTTCTGTGCCTGAGCTAGCCAGGCATGCTTTCCCCACCTGGGTTCCCTCAGTTGCTCATGGGGTGCCCCTGACTCAGCTTCATGCCTGTGGGGGTGGTTGGTCAGCACGGCAGTCTTTGAGGCCCCTCTGTCCCCAGGCCGGGCTGGCACCAGTCAGTCCTCACAGGAAGGCTCCTGGAGGGGCTGTGTGGTGGGGTGTTGGGTGCTTTGGCAGTGGGTAAGCCCTGGCCCTCTTCCTGCCGTTCCAG
Seq C2 exon
GAATCAGCCTCCTCATCCCCCCAGATGCCATACCCCGAGGGAAGATCTATGAGATCTACCTCACGCTGCACAAGCCGGAAGACGTGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000113763-UNC5A:NM_133369:8
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.275 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0079115=ZU5=PU(20.4=20.6)
A:
NA
C2:
PF0079115=ZU5=FE(28.2=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)