HsaINT0177862 @ hg19
Intron Retention
Gene
ENSG00000107731 | UNC5B
Description
unc-5 homolog B (C. elegans) [Source:HGNC Symbol;Acc:12568]
Coordinates
chr10:73052224-73053330:+
Coord C1 exon
chr10:73052224-73052311
Coord A exon
chr10:73052312-73053161
Coord C2 exon
chr10:73053162-73053330
Length
850 bp
Sequences
Splice sites
5' ss Seq
CCTGTGAGT
5' ss Score
7.21
3' ss Seq
TACCCTGTGTCCTCCTCCAGCCC
3' ss Score
9.31
Exon sequences
Seq C1 exon
GGGTCAGCTTGCTGGTGCCCAATGGAGCCATTCCCCAGGGCAAGTTCTACGAGATGTATCTACTCATCAACAAGGCAGAAAGTACCCT
Seq A exon
GTGAGTAGAGCCCCAGCCGCTGCTCCTTTTTCTTCCTCCCATCCCTTGCTGCCTGCCCACACGTGGCTCCCCTTCTAAGCCTGATGCCAAGACCAAACAGTCCTCCAAGGAAAGTATTAATCTTACTGTGTCCATATTGAAAACTTGCAGAACCAACACCGTAAATTGTAAAACTCAAAGGCGGTTGACAAGCTGGCTACAAGTGTGACAAAGGGCTGAATATCCTTACTATGTAAAGAGATTTTGTAGATCAATAAGAAAAAGTAAACATCTCACTGTGAAAATGGGCAAAGGATATGAACACGTGATTCACACACACTGTCTCACACAAACACACTGGCCAGTAGGTTATGAGAAAATGTTTAGTCTAATTTGCAGAGAAAACTAATGAAAACCACCACAAGGTATACTGGGATTTTTAAATTATTATTATTAAGGAATTTGCAAGGACCTTTTCCCAAATGATAATACCCTCTTGCTGGCAAGGGGGTGGGAACATGGCCTTCTGTGGCACGTGGCCGGGAGTATAGATTGGAACCAGCTCCCTGGAGGGCACTTTAGCGTGACCTATTGAAAACCTTCCAAGATTACACAACCTTGGAAAATATAAGCCAGGAATTTTGAGCTATGATAATGTTGCAGTGGAATAGCAAAAATCTGGAAACAACCTCAAGGTTCATGCCATTTTCTTTGCCTCCTTTGCCCCCATGACCTCTGGGAATGCAGAGCCCTGAGTGGCAAAGAGCTGCCCTCCACCTCCCGGGCCCTGGGCAGACTTGGGAGCCCAGCAGGAGCCTGCACCTTTGCCGAGCTCTTCACTGCCTCTCTCCTACCCTGTGTCCTCCTCCAG
Seq C2 exon
CCCGCTTTCAGAAGGGACCCAGACAGTATTGAGCCCCTCGGTGACCTGTGGACCCACAGGCCTCCTGCTGTGCCGCCCCGTCATCCTCACCATGCCCCACTGTGCCGAAGTCAGTGCCCGTGACTGGATCTTTCAGCTCAAGACCCAGGCCCACCAGGGCCACTGGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000107731-UNC5B:NM_170744:11
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0079115=ZU5=FE(28.2=100)
A:
NA
C2:
PF0079115=ZU5=PD(50.5=91.2),PF094705=Telethonin=PU(14.0=28.1)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGGTCAGCTTGCTGGTGC
R:
GCCTGGGTCTTGAGCTGAAAG
Band lengths:
238-1088
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)